The US weight loss market is absolutely massive (worth nearly $61 billion as of 2011), and weight loss pills account for about $1.5 billion of that pie. When people are spending that kind of money, count on the hucksters and shysters to be operating in force. The result is, well, what we see in the marketplace: an absolute glut of weight loss products and dietary routines, all advertised as better than the next. Well, the first thing you should know is that NO pill will cause you to magically lose weight.
Before you buy that next bottle of weight loss pills, check out the ingredients and compare them against this list.
In the spirit of full disclosure, I want you to know that the supplements I recommend in this article are not just what I personally use but they are from my supplement line, LEGION. You can learn more about LEGION and my goal to change the supplement industry for the better here. The acai berry craze has passed, but it still remains a solid top seller in the world of weight loss supplements. Use this workout and flexible dieting program to lose up to 10 pounds of fat and build muscle in just 30 days…without starving yourself or living in the gym. Carnitine is a compound that your body produces from the amino acids lysine and methionine, and it plays a vital role in the generation of cellular energy. While there is scientific evidence that carnitine supplementation can help with muscle recovery after exercise, does it have anything to offer in the way of weight loss? Well, it does have a mechanism that is of interest: it increases fat oxidation in the muscles.
What this means is it appears to increase the rate at which muscle tissue burns fat for fuel instead of glycogen. There’s evidence that carnitine can reduce fat mass and increase muscle mass in the elderly, but these effects were not seen when it was tested with overweight pre-menopausal women. Animal research has also failed to demonstrate any weight loss benefits when simply combined with a calorie-restricted diet. Animal research says no, as well as a human trial (which isn’t definitive due to flaws in design, but is worth noting).
Raspberry ketones are the primary aroma compound of the red raspberry (it gives the raspberry its smell), and it’s also found in other fruits like the blackberry and cranberry.
Well, it started with a couple animal studies. One demonstrated that raspberry ketone supplementation prevented weight gain by increasing lipolysis and fat oxidation, and the other backed up this mechanism. One of the rat studies was in vitro research. This means parts of living rats were removed to be studied in isolation, as opposed to research done with living, intact organisms (in vivo research). In vitro research is less definitive than in vivo because living organisms are incredibly complex, and sometimes in vitro findings just don’t pan out in vivo. There is insufficient evidence to support the use of low oral doses of raspberry ketone for weight loss purposes. Garcinia cambogia is a small fruit often used in Indian and Asian cuisine to impart a sour flavor. It’s a good natural source of hydroxycitric acid, and has received a lot of media attention recently as a weight loss aid.
Like many fad supplements, garcinia cambogia has some animal research on its side, but human research is contradictory and hard to interpret. A couple rat studies, such as this one, have demonstrated that garcinia cambogia can reduce weight gain during a period of overfeeding. Three studies with small sample sizes reported statistically significant, albeit small, decreases in fat mass over the placebo groups. Two studies found no difference in weight loss between the garcinia cambogia and placebo groups, including the largest and most rigorous study reviewed. The research currently available says that garcinia cambogia probably won’t help you lose weight, but if it did, the best you could hope for is a very small boost. A recent meta analysis of the 5 human trials available found that high dosages of chlorogenic acid via green coffee extract (400-800 mg chlorogenic acid per day) may induce fat loss, but researchers noted that the studies demonstrating this had high risks of bias due to funding sources (for-profit companies producing green coffee extract). However, until more research is done on it, and particularly unbiased research, green coffee extract’s value as a weight loss supplement is uncertain.
Caffeine, the world’s most popular drug, has more value to us fitness folk than the energy high. Part of maximizing the fat loss benefits of caffeine is preventing your body from building up too much of a tolerance, however. The best way to do this is to limit intake, of course. Personally I get my caffeine from my pre-workout PULSE, which contains a dehydrated and concentrated form of caffeine (caffeine anhydrous) shown to be more effective for improving performance than what is naturally found in beverages like coffee.
Beta-Alanine. Beta-alanine is a naturally occurring amino acid that reduces exercise-induced fatigue, improves anaerobic exercise capacity, and can accelerate muscle growth. Citrulline Malate. Citrulline is an amino acid that improves muscle endurance, relieves muscle soreness, and improves aerobic performance.


Betaine. Betaine is a compound found in plants like beets that improves muscle endurance, increases strength, and increases human growth hormone and insulin-like growth factor 1 production in response to acute exercise. Ornithine. Ornithine is an amino acid found in high amounts in dairy and meat that reduces fatigue in prolonged exercise and promotes lipid oxidation (the burning of fat for energy as opposed to carbohydrate or glycogen). Theanine. Theanine is an amino acid found primarily in tea that  reduces the effects of mental and physical stress, increases the production of nitric oxide, which improves blood flow, and improves alertness, focus, attention, memory, mental task performance, and mood. The bottom line is if you want to know what a pre-workout is supposed to feel like…if you want to experience the type of energy rush and performance boost that only clinically effective dosages of scientifically validated ingredients can deliver…then you want to try PULSE. The primary mechanism by which it accomplishes this is inhibiting an enzyme that degrades catecholamines, which are chemicals that mobilize fat stores to be burned for energy.
Green tea extract is an effective fat loss agent, as well as an effective weight management agent. Habitual caffeine consumption will reduce its effects, however, and you must take enough (400-600 mg of catechins per day, according to the research available).
Synephrine. This increases both basal metabolic rate and lipolysis, inhibits the activity of certain fat cell receptors that prevent fat mobilization, and increases the thermic effect of food (the “energy cost” of metabolizing food). Naringin. This stimulates the production of a hormone called adiponectin, which is involved in the breakdown of fat cells, and that it activates a type of receptor in fat cells that regulates fat mobilization (the PPAR? receptor).
Through these mechanisms, naringin also works synergistically with synephrine and hesperidin to further accelerate the basal metabolic rate. Epigallocatechin gallate (EGCG). This inhibits the activity of a different enzyme also responsible for breaking down neurotransmitters that induce lipolysis. Forskolin. This increases blood plasma and intracellular levels of a molecule known as cAMP.
Research has show that supplementation with forskolin accelerates fat loss and increases testosterone levels.
The bottom line is if you want to lose fat faster without pumping yourself full of stimulants or other potentially harmful chemicals…then you want to try PHOENIX. Yohimbine accelerates weight loss, but only works if you’re training in a fasted state. I’ve cut both with and without fasted training and yohimbine and I can say with absolutely certainty that with is noticeably faster. When used properly (high enough dosage, fasted state, before exercise), yohimbine speeds up fat loss.
In terms of which specific yohimbine supplement I recommend, you’re probably not surprised that I’ve included a clinically effective dosage in every serving of my pre-workout fat burner FORGE.
Citicoline. CDP-choline (also known as citicoline) is a chemical that occurs naturally in the brain that increases levels of another chemical called phosphatidylcholine, which is vital for brain function. Research shows that supplementation with CDP-choline improves attentional focus, and I included this in FORGE because most people find fasted training more mentally draining than fed training and CDP-choline can help counteract this. You see, depending on how you eat, train, rest, and supplement, building muscle and losing fat can be incredibly simple or seemingly impossible. I've also learned a lot about what DOES work, and I wrote Bigger Leaner Stronger and Thinner Leaner Stronger to teach you EVERYTHING you need to know to build the body you've always wanted. I'm Mike and I'm the creator of Muscle for Life and Legion Athletics, and I believe that EVERYONE can achieve the body of their dreams. If you like what I have to say, sign up for my free newsletter and every week I'll send you awesome, science-based health and fitness tips, delicious "diet-friendly" recipes, motivational musings, and more. And yup diet and exercise are most responsible, but the combined effects of a few of these naturally effective fat loss aids can add up. Just like you, we want to find the answers to what the best weight loss pills are and why they work.
Keep in weight loss pills that actually work mind that many of postings, so all added ments receive Undecided, Positive or general vote is. Caffeine, Green Tea or any other fat burners with proprietary blends where you have no idea how much. Doctors usually prescribe them only if your weight, weight loss pills that actually work like type 2 diabetes high blood pressure. Tagged Does Hydroxycut Really Work For Weight Loss?, Supplements and Herbs for Weight Loss, weight loss pills for women that work, Which Weight Loss Pills Actually Work? You have to regulate your caloric intake to lose weight (you have to feed your body less energy than it burns every day).
The truth is the majority of the supplements you see in the magazines and on the shelves aren’t going to help you reach your goals faster.
The human and rat body just isn’t similar enough, and this is especially true when talking about metabolic functions. The mechanism by which it accomplished this is the suppression of fatty acid synthesis in the liver (it reduced the amount of fat the body could make from the excess calories).
It’s similar to regular coffee beans, but has high amounts of a substance known as chlorogenic acid.


If consumed too acutely and regularly, tolerance builds (which reduces its effects) and withdrawal symptoms are common.
It contains a large amount of a substance known as a “catechin,” which is responsible for many of tea’s health benefits.
This also makes green tea extract work synergystically with caffeine–caffeine increases catecholamine levels, and green tea extract extends the amount of time they spend in the blood.
Like naringin, this also stimulates the production of adiponectin and activates the PPARa receptor.
When cAMP is high, it signifies a lack of ATP (the most basic form of cellular energy in the body) and thus initiates a process to make more ATP by burning through energy reserves (body fat). So much so that I think the biggest benefits of fasted training are that it lets you use yohimbine and it makes the other supplements discussed in this article more effective. HMB is an extremely effective anti-catabolic agent, which means it’s very good at preventing muscle breakdown. For instance, if you can lose an extra 3-4 pounds of fat over the course of 6-8 weeks, I think that’s worth it. The reality is no natural weight loss supplements will help unless your diet is also in (and exercise helps as well, of course). In regards to the Yohimbine supplement, my recommended dosage would be around 20 mg (I weigh 211lbs). I tried it out on my last workout after taking my pre workout and glad to say nothing negative was noted. Doctors usually prescribe them only if your weight, like type 2 diabetes higher, blood pressure.
I am on a prescription medicine until Dec but would really like to know what is available over the counter after that! And because its used to turbo-charge the heart, some doctors have even used it for patients whove suffered from heart failure.
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