Solar lentigenes is the medical term for those pesky spots that we often refer to as liver spots, sun spots or age spots. Age spots are generally flat and may range in color from deep yellow to gray, brown or black. All treatments should be supported by effective sun protection blocking against both UVA and UVB rays. Although not cosmetically appealing, age spots tend to be harmless so medical attention generally isn’t required. Public DomainBy downloading this image, you agree to abide by the terms of use of this license. Primary Ovarian Insufficiency (POI) or Premature Ovarian Failure (POF) are a loss of ovarian function before the age of 40. Although POF is sometimes called early menopause, women may continue to have irregular menstrual cycles, and some women can conceive naturally. While the actual cause is still unknown, it has been ruled out that 10 to 30 percent of affected women have an autoimmune disease such as Crohn’s disease, hypothyroidism, rheumatoid arthritis or lupus erythematosus.
Menopause in early 20s that are affecting up to 1 million American women could be due to abnormal individual genes or chromosomes. Most causes of POI are idiopathic, meaning it has no obvious cause, which is why it is important for women to be tested because some known causes are associated with their health or their family’s health.
Menopause usually occurs at age 51 but premature ovarian failure can occur at any age usually around age 27.


These spots of darker skin may appear on anyone and are a common occurrence in most individuals by the time they reach 40. They vary in size, but tend to be small and can be found on areas such as the face, arms, shoulders and hands – those areas most exposed to the sun. Individuals with a fair complexion are more prone to age spots, but even those with darker skin may develop them. Often referred to as bleaching creams, products containing hydroquinone, kojic acid, alpha hydroxy acids or other botanical skin lighteners (link) can help to fade spots.
Skin appears lighter as the area heals, but this process does come with the slight risk of permanent scarring or discoloration. However, if your age spots are very dark or their appearance has changed, it may be a sign of skin cancer. POF affects women from teenage years to 30s, but it could happen at any age or any time, and they are at greater risk of estrogen deficiency, osteoporosis, and heart disease but it could be managed by Hormone Therapy.
Thirty percent of women have familial ovarian failure and galactosemia characterized by enzyme problems like adrenal hyperplasia. If you have Turner syndrome, one X chromosome is missing, which can cause reproductive system abnormalities, especially primary ovarian insufficiency. While this condition is quite rare, women with Y chromosomes need to have their ovaries removed because it can cause ovarian tumors. Hysterectomy with both ovaries removed or treatment for Hodgkin’s disease or leukemia could also induce premature menopausal. Although viral infections such as mumps or cytomegalovirus have inconclusive evidence, it was thought to trigger premature menopause.


If you are one of the 1 million American women diagnosed with early menopause or POF, you should talk to your health care provider about proper treatment and management if you are thinking about getting pregnant. My hormone levels are normal and I don’t have other symptoms other than I was told I have a very small uterus. Adding a prescription retinoid or non –prescription retinol as found in Green Cream can hasten the process. I am concerned at the lack of concern by doctors that don’t check for other problems. I know I should be happy not having a cycle, but I can’t help but worry when there is no further explanation. My grandmother had a tumor on her pituitary gland and I wonder if I might have underlying problems or issues that have not been found or should be looked into. I got my first cycle at age 14 and each cycle after came a year or more in between then stopped completely at age 20. I am now getting swollen lymph nodes on left side of neck in clavical area that I have an ultrasound appointment for and just yesterday felt a lump under my skin on my lower back.



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