A woman who was genetically born a man and was told she would never become a mother has given birth to twin girls.
Throughout puberty she did not have periods, and doctors later discovered she had no reproductive organs thanks to a condition called androgen insensitivity syndrome. A ray of hope came in 2007 when a new specialist at Royal Derby Hospital found a tiny womb missed on previous scans. The first step was a course of hormone tablets to give her the right levels of progesterone and oestrogen, which would stop her suffering osteoporosis and create an environment in which her womb could grow.
In 2011, Mrs Haynes was told her womb was ready for IVF – but was dealt another blow when she was told her local NHS trust would not fund it. Doctors told her she had only a 60 per cent chance of pregnancy – so when two tests came back positive, she was ecstatic.
And when Mrs Haynes went for her six-week scan, it was a shock to discover both eggs had taken and she was expecting non-identical twins.


Nine years after hearing the crushing news that she would never be a mother, Mrs Haynes gave birth to Avery and Darcey. Androgen insensitivity syndrome (AIS) affects the normal development of a child’s genitals and reproductive organs. A child born with AIS is genetically male, but their genitals may appear to be female or somewhere between male and female. In early stage pregnancy, all unborn babies have identical genitals, regardless of their gender. As a baby grows inside the womb, they develop either male or female genitals, depending on which pair of sex chromosomes they receive from their parents: XX or XY.
Sex chromosomes are a pair of DNA molecules (X or Y) that play a vital role in a baby’s sexual development. The presence of a Y chromosome is important for the development of testes and prevents ovaries developing.


The testes produce male hormones called androgens, which usually cause male sex organs, such as the penis, to develop. At the age of 19, she was told by doctors she had XY chromosomes, so was genetically a man – and would never conceive. If there’s no Y chromosome, the female reproductive system and genitals will develop.



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