It had been a long week of moving from Brooklyn to Queens and having no kitchen, I had eaten out every single day. I found that the diarrhea would actually respond quite well to a high-carb diet of "gentle" foods like pumpkin, apple-sauce, and broth. I was because these foods seemed to have a positive effect and the Queens experience that I've shifted away from low-carb paleo and actually pretty much shifted away from the typical conception of paleo. The short story on butyrate is that it is made in the colon by fermentation of carbohydrates.
Otherwise, conventional low-carb diets generally do a very poor job of generating butryate in the populations studied.
It was pretty fatty, but I am personally a bit more interested in the high-protein part since contrary to popular belief, protein is fermented in the colon.
Overall this paper and many others on the effect of low-carb on gut bacteria seem to paint a bleak picture. In the meantime I continue to enjoy success from diet that includes ample amounts of carbohydrates that work for me, like rice and buckwheat, and keeping my protein low. I'm hoping my AHS presentation will be up soon because I talk a lot about gut bacteria and a particular metabolic known as butyrate. Butyrate has many important roles, but I would sum up its main roles as promoting satiety, reducing inflammation, and protecting the colon. However, to describe them as just low-carb is a disservice to the diversity of their diet. In a previous post I discussed the many plants they eat.


There are several papers on this, the most recent being High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. What about all the success people have with low-carb diets and diets that focus on controlling carbs like the Specific Carbohydrate Diet?
It may be because they aren't thinking about fat. Linoleic acid and butyrate synergize to increase Bcl?2 levels in colonocytes implies that the colon-cancer preventing effects of butyrate may be muted by excess linoleic acid and enhanced by added DHA. Stop being tricked by so-called “health foods” and start eating the first and only veggie meal plan dedicated to helping you lose belly fat and sculpt your body….
I had thrown caution to the wind and hadn't bothered trying to be paleo beyond avoiding gluten and junk food. Before "paleo" I had struggled with IBS (constipation, gas, and diarrhea) and GERD (chronic acid reflux). Currently it is mainly being studied as having a role in obesity, inflammatory bowel disorders, and colon cancer. I think low-carb can play a role in fighting disease, but I think it's a mistake to carry on this kind of diet long term. Eating 1,500 calories a day is easy and delicious when you follow this diet meal plan to lose weight.
When I started paleo, I found low-carbing did an amazing job eliminating the worst IBS symptoms and my GERD disappeared. In the high-protein diets branched-chain fatty acids (BCFAs) isovalerate and isobutyrate were increased.


The SCD doesn't advocate low-carb forever, but healing and then adding in carbs cautiouly to figure out which ones are benign.
Do your sums and you'll quickly realise the Lite n' Easy approach represents great value for money.
But two years into it, I started having different stomach problems, particularly intermittent severe diarrhea. Perhaps low-carb can work in the long-term if small amounts of certain carbohydrates or foods with SCFA are consumed (fermented foods or butter, which is high in butyrate), but there is little research into this. IBD patients have low levels of it in the colon and administering it reduces symptoms significantly. In vitro NOCs have shown carcinogenic effects, but there haven't been many in vitro studies. Plant-derived phenolic compounds (such as ferulic acid) were reduced in the HPLC diet, but increased in the HPMC diet compared to M. Another caveat is that butyrate is present in certain foods, but this has been poorly studied, which is unfortunate.



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