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Novel approaches for maintaining colonic health might include the addition of anti-inflammatory bacterial factors (postbiotics) and could therefore be a safer alternative to the use of whole bacteria.CR ?? ??? PR(Proposed Recommendation)? ???? ??? ??? ????? ? ?? ?? ??? CSS 2.1 ?? ??? ?? ??? ? ?? ??? ???? CR ??(6??)? ?? ??? ??? ??? ????? ??? ???? ???? ???? ??? ?? ?? PR ??? ??? ???, ??? 4??? PR ??? ???? ?? ??? ? ? ?? ???? ??? ?? ?? ????? ??? ????. Future CRC preventive and screening strategies need to identify the mechanisms by which these microbial factors contribute to homeostasis.

Their relative importance to the host when the system is in disequilibrium might include direct effects on the microbiota, such as direct anti-pathogenic activities, or support of beneficial bacteria (including lactic acid bacteria). Alternatively, such compounds might have regulatory functions on the host innate and adaptive immune system.


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