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These medications are prescribed as early as possible for acute and recurrent disease to decrease severity, duration and viral shedding. Acyclovir given at 36 weeks gestation reduced the risk of recurrence at delivery, the risk of viral shedding at delivery and cesarean section rate for recurrent genital herpes. The first episode of acute herpes is treated with acyclovir 400 mg 3 times a day for 7-10 days.
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Suppressive therapy is 500 mg once a day or 1 g once a day for patients was greater than 9 recurrences per year.
These drugs are very safe and do not require laboratory monitoring when used for a short duration.


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