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admin 05.06.2014

In general, there are some mixed confusion about common cold sores around the mouth and whether are all cold sores caused by herpes virus. However, there are many individuals who got the standard cold sores mixed up with canker sores (which is also sometimes refer to as cold sores by laymen) or even with shingles (also another form of herpes infection with similar symptoms that may occur around the mouth). Oral herpes is also commonly known as cold sores (or fever blisters) due to the fact that the infection or outbreaks usually occur when the immune system of an individual is weaken or when someone is having an illness (like during a fever or common cold).
During an outbreak, watery blisters will form, burst open as painful sores, later dry, crust and then heal. Known as aphthous ulcers or mouth ulcers, canker sores are small painful ulcerations that form on the soft tissue linings in the mouth, or on the gums.
Also refered as herpes zoster, shingles is a reactivation of the varicella-zoster virus (VZV) that causes chicken pox. Shingles is most commonly mixed up with the herpes simplex virus (HSV) since symptoms of an outbreak can be quite similar and painful. In most cases, shingles appear on the body but there are rare cases that the rash may appear on the face and mouth.
During an outbreak, shingles is highly contagious to babies and adults who never had chicken pox. In the past, cold sores have generally been herpes simplex virus type 1 (HSV-1), however, due to increase incidences of oral-genital contact during sexual activity between partners, people can get HSV-1 on their genitals and cause genital herpes.
On the other hand, individuals can also contract herpes simplex type 2 (HSV-2) on their mouth if oral sex is performed on a partner with HSV-2 genital herpes infection.
Note: If a person gets genital herpes from a partner who has HSV-1 during oral-genital sex, the genital herpes infection will be a type 1 herpes virus and will not become a type 2 genital herpes infection.
Generally speaking, there are many people out there who do not considered cold sores as a form of STD if the herpes simplex virus is type-1 since so many people are exposed to it and many associate the stigma of STD as a form of disease that are transmitted through vaginal or anal sex.
However, since the medical discovery that it is possible to transmitted HSV-2 to the mouth during oral-genital sex, cold sores (oral herpes) is now considered an STD.
Individuals who notice symptoms of small blisters around the lip or mouth should schedule a visit with their physician to get diagnosed to distinguish whether it is a HSV-1 or HSV-2 infection.
In general, if the cold sores are visible, the health care professional will perform a viral swab test called viral culture to get a sample of the sore to be tested in a lab.
For initial outbreaks of oral herpes, the symptoms are usually quite severe and painful and doctors may prescribe oral antiviral medications such acyclovir (zovirax), famciclovir (famvir) or valacyclovir (Valtrex) to help reduce the pain and speed up the healing of the sores. Recurrent outbreaks of cold sores are generally less painful and topical creams such as HERP-B-GONE or Docosanol 10% (Abreva) can be used to reduce the pain, itching as well as the healing of the sore on the skin. Additional complementary treatments such as taking vitamin C and lysine supplements may help reduce the frequency of the outbreaks.
Information provided on this site is not intended as a substitute for medical advice on any health concerns you may have. By age 40, nearly 90% of adults have been exposed to the herpes simplex virus-1 (HSV-1), which causes cold sores.
Until now, research has generally concentrated on keeping HSV1 inactive — and preventing cold sores from ever showing up.
Understanding how to override the microRNA could allow scientists to activate the virus and then kill it using acyclovir.


The theory is that by activating the virus, then preventing it from returning to hibernation, which is when researchers think it gains strength, it can be completely eradicated. Cullen and his colleagues, as well as several biotech firms, are already investigating such treatments and how best to deliver them.
So, it may not be surprising to know that people who had the herpes simplex cold sores been told that they have canker sores or shingles, and vice versa. Most commonly, herpes simplex virus type 1 (HSV1) causes the primary and recurrent outbreaks of small painful blisters, especially on the lips and around the mouth which is refer to as oral herpes. It is primarily spread via contact with oral secretions while sharing a glass of drink, during kissing or through oral to genital sex with an infected individual. The association of cold sores as cranker sores or vice versa often comes from laymen who do not know how to differentiate between the two condition and which is what causes the confusion and mixed up.
Even when the chicken pox rash is gone, the varicella-zoster virus continues to remain latent in the nerves of the body until is is reactivated again as shingles that causes painful blisters on the skin that typically affects one side of the body. However, the key difference is shingles rarely recurs and if it does get reactivated, it will only occur in 3% of adults aged 60 or older due to a weak immune response to the varicella-zoster virus. However shingles is not related to as any form of sexually transmitted diseases such as the herpes simplex virus that causes herpes genitalis, or oral herpes. The infection can be transmitted via air from breathing and coughing or skin to skin contact, and once infected, these people will develop develop chicken pox. The same goes to say that herpes simplex type 2 cold sores can cause a HSV-2 genital herpes infection.
If there are no visible physical sores or if the sores have healed, clinicians may opt for a blood antibody test called the Western blot herpes antibody test to look for antibodies to the herpes virus in the blood. But the Duke researchers took the opposite tack: figuring out precisely how to switch the virus from latency to its active stage. Cullen believes that a drug could be developed to block the microRNA that suppress HSV-1 into latency; once it's active, acyclovir can be used to destroy the virus permanently. However it can also be transmitted if someone comes into physical contact by touching an open cold sore. Medically speaking, all cold sores are herpes however canker sores are not herpes related and they are definitely not contagious. Because of this large number of victims, cold sore treatment options are abundant at your local stores.These over-the-counter cold sore treatment remedies are primarily designed and sold for comfort - and they do a good job for that. Now you need to apply hot tea bags to get rid of cold sores quickly.Do not heat the bags in the microwave. For those who do, however, cold sores are a painful and permanent nuisance, always erupting in the same location, at the original site of infection on the lips or mouth.
In its latent stage, HSV-1 produces a single molecular product, called latency-associated transcript RNA, or LAT RNA.
Cullen suggests that this new research may also eventually be applied to other latent viruses, such as herpes simplex virus-2 (HSV-2), which causes genital herpes, or the chicken pox virus, which causes shingles in adults.
Worse yet, once you're infected with the virus that causes them, you're stuck with it for good. Once HSV-1 enters the body it hunkers down for life, most of the time hiding dormant in the cranial nerves near the spine.


Unlike most messenger RNA, LAT RNA doesn't produce proteins, so scientists have never been able to determine LAT RNA's exact function.
Cullen warns that some patients, especially those suffering genital herpes, may have to take acyclovir on a regular basis (HSV-2 is a hardier virus), but for people with HSV-1, the virus could be eradicated with just one dose. Comfort is great, but the quicker the healing the better.Below are several well-proven cold sore treatment tips that I would like to share with you right now.
But landmark research reported today by microbiologists at Duke University may offer the potential for a cure.
The virus can be triggered by outside stress, such as exposure to sunlight, a fever or emotional distress. But by inserting the LAT RNA into mice, Cullen found that it breaks down into even smaller strands called microRNA.
After it's active and a cold sore appears, it's treatable with the drug acyclovir, marketed under the name Zovirax, which kills replicating HSV-1. Researchers then discovered that it was the microRNA that blocked production of the protein that activates HSV-1.
CALCIUM.Calcium is the main mineral used by your body to keep you in a healthy alkaline state. But the mystery has been how to eliminate the virus while it's hiding, before it produces unsightly symptoms.
When acid, your body is low in oxygen and susceptible to infection and disease.Your pH balance is a measure of your acid or alkaline state. Cold weather, stress and certain foods are the main reasons your body might tend toward the acid side - and the main triggers for cold sores.As a cold sore treatment, make sure you are getting plenty of calcium every day with food and supplements. Lysine works best when you use it as an internal remedy for oral herpes and cold sores.Lysine effectively neutralizes arginine, another amino acid.
Arginine is the main protein necessary for the herpes simplex virus to replicate - which creates the visible cold sore.
Quite often you will find that combining several will be the best cold sore treatment for your particular needs.
Lysine pushes it out of your cells so it is not available to create new virus.Your key to successfully healing and preventing cold sores with lysine is to flood your cells with it.
Avoiding high arginine foods is also wise during an outbreak.The easiest and most convenient way to get lysine, however, is to use lysine capsules. You can more easily control the dosage - and you don't have to give up the foods you love.Most people who use lysine for an active cold sore treatment take about 5000 to 7000 milligrams spread throughout the day. Drinking the tea helps, but it is a much better cold sore treatment if applied directly to the wound.Soak a few tea bags and freeze them. As soon as you feel the warning signs of a new outbreak (tingling, itching, burning sensations) hold a frozen bag to the area.



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