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admin 17.09.2013

New research into a 2,000-year-old Chinese herbal remedy derived from the roots of the blue evergreen hydrangea, has shown that the medicine could be used to help treat autoimmune disorders.
Also known as Chang Shan, the herb weakens the defective immune response related with many autoimmune disorders such as rheumatoid arthritis, multiple sclerosis, and psoriasis. Used in China for centuries to help reduce fever and fight malaria, the herb’s active ingredient, febrifugine, is considered too toxic for use by Western standards, so the U.S.
In 2004 scientists managed to pinpoint the cells targeted by halofuginone, cells known as Th17.
Previous studies in mice have shown that halofuginone protects against harmful Th17 cells without affecting other beneficial immune cells. The new study has shed light on how this process works – the herbal extract appears to trigger a series of events critical to immune regulation, by letting cells know when they need to conserve resources.
Whitman likened the situation to how we conserve our energy during a power outage, only using power when absolutely necessary.
By triggering this response, researchers say halofuginone may also help them understand how the pathway affects autoimmune disorders and lead to better treatments. One of the more ethnically and culturally diverse neighborhoods in cosmopolitan Honolulu is Chinatown, a microcosm of today’s Honolulu. Download the minube app and travel like never before Download Where'd you like to go?
A philosophy and practice for the past 80 years, and three generations of sons, at Cheng Woh Medical Hall – a Chinese herbal shop located in the UNESCO World Heritage site of George Town in Penang. Many of the original Chinese herbal recipes are still produced and sold in the shop, while others Mr.
Army scientists created a derivative called halofuginone (HF), but it was abandoned when research failed to uncover how it actually worked. Experience Honolulu’s eclectic Chinese-inspired culinary scene and open-air markets that define this culturally diverse neighborhood.

It provides a real cross-cultural experience with influences from its Chinese, Japanese, Korean, Filipino, Thai, Vietnamese and Hawaiian residents.Next to central downtown Honolulu on Oahu, Chinatown is a 15-square block area bound by Nu`uanu Stream and River Street on the north, Bethel Street south, and by Beretania and King Streets east and west.
Sundrud, PhD, Anjana Rao, PhD, and their colleagues showed that halofuginone does indeed inhibit Th17 cells. Chinatown History In 1852, the Chinese were the first immigrant laborers to arrive in Hawaii to work on the growing sugar cane plantations.
Completing their labor contracts, many relocated to the Chinatown area of Honolulu to enter the business world. With its exotic mix of cultures and peoples, Chinatown gained a disreputable name over time as an undesirable slum area known for its saloons, debauchery, drugs and dens of ill repute.
It is one of the most famous shops in this city of over 6 million inhabitants, provincial capital of Zhejiang. Roots used in traditional Chinese medicine for millennia, medicinal plants and drug mixtures are some products you can find here. In an effort to control an outbreak of the bubonic plague, the Board of Health and Fire Department attempted to do a controlled burn of rat-infested buildings. However, the fires quickly got out of control and many buildings were soon engulfed by flames.
The Great Chinatown Fire burned for 17 days, destroying 38 acres of property and leaving 4,000 residents homeless. Somewhat ironically, the Board of Health declared the area plague-free four months later.Today, Chinatown’s former reputation for debauchery and worse has been toned down considerably. While there are still a couple of seedy taverns and bars along Hotel Street that are probably best avoided, Chinatown is a lively and colorful community to explore.Chinatown Makeover and Attractions In recent years, Chinatown has initiated a community makeover.
Buildings have been renovated to meet historical codes in structure and appearance, giving Chinatown an old-yet-new look.
Now much cleaner and more appealing, Chinatown retains its cultural essence with its Chinese herbal medicine shops, dim sum and noodle restaurants, manapua (meat-filled steamed dumplings) shops, art galleries, and the hustle and bustle of its open-air markets and vendor stalls.Discovering Chinatown Today’s Chinatown is a fun place to stroll through, where you can enjoy a market visit, eat some great dim sum and noodles, or just take in the cross-cultural diversity of Honolulu’s most colorful and historic neighborhood.

For Chinatown Honolulu shopping, colorful open-air markets include the Oahu Market (established in 1904) at the corner of King and Kekaulike Street, the Kekaulike Market on the Kekaulike Street Mall between King and Hotel streets and Mauna Kea Marketplace on Mauna Kea Street between Hotel and Pauahi streets. At the markets, you’ll find fresh fish and seafood shops, butcher shops with racks of roast char siu pork, chicken and duck, plus produce tables piled high with colorful fresh exotic vegetables, fruits and produce of all kinds. The markets make for an interesting shopping adventure!Be sure to visit one of Chinatown’s cultural icons—the Chinese herbal medicine shops.
Many of these shops have more than 1,000 kinds of dried plants, bark, roots, leaves, twigs, flowers, mushrooms and fungi, and other mysterious plant and animal products on its shelves, all used to treat various ailments and illnesses. Small Chinese bakeries, food stores, general stores, Asian import stores, flower and lei shops, art and antique galleries and more round out Chinatown. It all makes for an exciting and colorful self-guided exploration of this cosmopolitan neighborhood of Honolulu.
Recommended Chinatown Restaurants You say you’re hungry after all that walking and exploring of Chinatown? The inconspicuous Mei Sum Dim Sum (65 North Pauahi St.), features a wide selection of Hong Kong-style dim sum. Adventurous diners will appreciate Little Village Noodle House (1113 Smith St.) a small restaurant with a big menu of creative Northern Chinese and Szechuan cuisine.
It’s an opportunity to immerse oneself in the diversity and cross-cultural experience that is the heart and soul of one of the Pacific Rim’s most cosmopolitan cities.

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