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admin 08.08.2015

People who suffer from cold sores are more likely to develop Alzheimer’s disease, newspapers reported today.The Daily Telegraph said that a study has found that exposing brain cells to the herpes simplex virus (HSV-1) that causes cold sores, results in large quantities of a protein to build up in the brain - a state that is commonly found in Alzheimer’s sufferers. While these studies indicate an avenue for further research, at present they do not provide convincing evidence of a link between Alzheimer’s and the HSV-1 virus.These were studies under experimental conditions where samples of brain cells were exposed to high levels of the virus, and as such cannot be considered a direct parallel to the situation where infection occurs in the living human body. With an account you can keep track of pages on the site and save them to this tab, which you can access on every page when you are logged in.
This effect is especially apparent in people who have a type of gene variant that is “carried by 30% of the population and half of all Alzheimer’s patients”.
Herpes simplex virus infection causes cellular ?-amyloid accumulation and secretase upregulation. The Telegraph, October 31 2007Cold sore sufferers more likely to develop Alzheimer's, says research.


A vaccine for HSV-1 is also a long way off.Alzheimer’s disease and its possible causes are still poorly understood. At this stage people with the extremely common, recurrent infection of cold sores, should not think that they are at an increased risk of developing Alzheimer’s.Where did the story come from?
This research was carried out by Matthew Wozniak and colleagues of the University of Manchester. The study was published in the peer-reviewed scientific journal: Neuroscience Letters.What kind of scientific study was this?
This was a laboratory study using human and animal brain cells to see whether infection with HSV-1 increases the build up of the amyloid protein that is seen in the brains of people with Alzheimer’s disease.The researchers used two special types of brain cancer cell that can be grown in the laboratory.
They also conducted other experiments on the human cells and on monkey kidney cells to look at how HSV-1 might affect amyloid protein levels.What were the results of the study?


The researchers found that the cells that were infected with HSV-1 had increased quantities of both types of amyloid protein, and decreased levels of the precursor protein.
They found that mice infected with HSV-1 had a build up of one form of the amyloid protein in their brains, but uninfected mice did not.What interpretations did the researchers draw from these results? The researchers conclude that infection of brain cells with HSV-1 increases the amount of amyloid protein present. They say that their findings “show that HSV-1 can directly contribute to the development of senile plaques” and that the findings “further support our contention that treatment of Alzheimer’s dementia patients with antiviral agents would reduce, or even prevent further cognitive decline”.What does the NHS Knowledge Service make of this study?



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  • 10, 08.08.2015 at 17:57:27
    Not any treatment for herpes, however can be restricted with oral physique's.
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    L-lysine dietary supplements of about definitely.
  • KickBan, 08.08.2015 at 21:54:40
    Simplex virus kind 1 (HSV-1) you'll.