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Xiangtao Meng, an Institute for Critical Technology and Applied Science doctoral scholar and graduate student in the College of Natural Resources and Environment. In drug-delivery research, finding a pharmaceutically active molecule is only half the battle: the drug must also be able to safely reach its target. Xiangtao Meng, a fourth-year graduate student in the College of Natural Resources and Environment, has developed a new technique to make that easier.
Taking medications orally is typically much more practical for patients than methods like intravenous injections, but the bioavailability of a druga€”the amount that actually reaches the bloodstreama€”often suffers.
In order to reach the circulatory system, a drug taken orally must dissolve in the digestive tract. That means that patients have to ingest more of a drug to get the therapeutic dosea€”increasing the cost, risk of side effects, and the likelihood that the patient will simply miss a dose. Dispersing a drug in a polymer matrix protects it and suppresses the formation of insoluble crystals.
Because medications have broadly diverse chemical structures, properties, and dosing and delivery requirements, finding the right polymer matrix to work well with most drugs involves making and testing many different options. Meng's chemistry offers a new way to make a wide variety of polymer matrices using cellulose as a starting material.
Cellulose is an attractive material for drug delivery because it's nontoxic, breaks down into components that are already present in the body, is water-permeable, and can survive the stomach's acidic environment. Unlike many synthetic polymers, which are often made from petrochemicals, cellulose is derived from wood, a renewable resourcea€”supporting the mission of the College of Natural Resources and Environment to advance the science of sustainability. When Meng first took on the project, there were only a handful of methods to make cellulose derivatives, limiting the number of options for drug delivery.
Meng decided to investigate whether he could modify cellulose using a technique called olefin cross-metathesis, a reaction developed in the 1970s and for which three chemists jointly received a Nobel Prize in 2005. Olefin cross-metathesis is a very versatile reaction, and could be used to make a huge array of potential drug-delivery matrices, but it had never been applied to cellulose. Meng's method will allow chemists to use a single readily available, renewable starting material to develop a wide variety of polymers specifically tuned to carry many different pharmaceutical targets. Meng, who is part of the Macromolecules and Interfaces Institute organized under the Institute for Critical Technology and Applied Science (ICTAS), recently won the American Chemical Society's CELL Division Graduate Student Award for this work. He has been able to produce a wide array of modified cellulose samples, which he sends to collaborators in a drug-delivery group at Purdue University.
Meng, an ICTAS doctoral scholar from Shandong Province, China, is now working on incorporating another type of chemical reaction that will allow even more versatilitya€”like "growing apples and peaches on the same tree," he said.
It will also open the door to a wider array of potential applications, like the synthesis of antibacterial hydrogels for wound dressing, he said.
A team of researchers has uncovered critical information that could help scientists understand how protein polymers interact with other self-assembling biopolymers.
The same tiny cellulose crystals that give trees and plants their high strength, light weight and resilience, have now been shown to have the stiffness of steel. Purdue researchers have discovered the structure of the enzyme that makes cellulose, a finding that could lead to easier ways of breaking down plant materials to make biofuels and other products and materials.
Polymer nanoparticles that release medicine at controlled rates inside cells have the potential to enhance the efficacy of many clinical drugs. Thermally-based industrial chemical separation processes such as distillation now account for 10 to 15 percent of the world's annual energy use. Micrometric and sub-micrometric contaminant particlesa€”what most of us call "dust"a€”can cause big problems for art conservators, the electronics industry, aerospace engineers, and others. If you have been diagnosed with, or suspect you may be having a genital herpes outbreak or infection you are likely anxious to find effective forms of treatment are available to you. First you should know there is no cure for the virus, but there are several effective herpes medications to help manage the outbreaks and relieve the symptoms. Several decades ago, treatment options for herpes included the direct application of deoxyglucose or the actual removal of infected areas by surgery. If you are searching for a natural and safe herpes treatment, try H-Cold Sores – two proven and very effective formulas for preventing herpes outbreaks and eliminating herpes sores and blisters including those pesky cold sores that are so common. Less than 20-years ago anti-viral medications (Valtrex, Acyclovir, Famvir) for oral use first came on the market and studies indicated that these were safe and effective. In the last few years, a number of non-prescription medications made from essential oils and other natural products have become readily available. An unpredictable and common disease, bipolar sometimes has devastating effects on the patient if not treated in the early stages.
Certain drugs are administered to stabilize the mood swings of the person and to bring it to a normal level. Different people respond differently to the medications and so sometimes many medications will have to be tried out before one is found which brings relief to the particular person. The medicines should not be stopped as soon as one feels better; it has to be taken for a long time.


Therapies are a must in the treatment for bipolar disorder because the patient should learn how to deal with the problems that arise out of the disease and increase one’s self esteem. The family should be aware of the seriousness of the disease and be supportive to the patient when frequent mood swings occur. Living with a person with bipolar disorder is not at all easy and the members should know more about the disease and help when the patient gets depressed and create a happy and healthy environment for the person. Meditation as well as yoga has been found to be very effective in the treatment of bipolar disorder as it helps one control one’s mind and remove all negative thoughts away. Fibromyalgia is characterized by chronic widespread pain in muscles, ligaments and tendons, numbness and tingling, palpitations, multiple tender points, tension, fatigue, migraine headaches and sleep disturbances. Natural products such as Topical BioMedics' Topricin Pain Relief and Healing Cream are a safe, natural alternative to oral pain medications to help relieve symptoms of pain associated with fibromyalgia.
The soft tissue pain of fibromyalgia is often described as a deep aching, gnawing, shooting or burning sensation that often ranges from mild to severe.
Topricin is patented for the treatment of pain associated with fibromyalgia and is specifically formulated for pain relief that works at the molecular level to help the body heal the damage that is causing the pain. Women have reported that by using Topricin regularly they feel better and healthier and are staying more active. Lou Paradise, CEO of Topical BioMedics and product formulator of Topricin says that Topricin has been effective in resolving pain for women suffering from fibromyalgia with many reporting they have more energy and are staying more active. Women face unique health challenges and every day millions of women suffer from chronic pain. Fibromyalgia is complex chronic pain condition that affects 10 million people and 90% of those diagnosed are women. The condition is characterized by chronic widespread pain in muscles, ligaments and tendons, numbness and tingling, palpitations, multiple tender points, tension, fatigue, migraine headaches and sleep disturbances. Natural products such as Topical BioMedics' Topricin Pain Relief and Healing Cream are a safe, natural alternative to oral pain medications to help relieve symptoms of pain associated with fibromyalgia. ABOUT TOPICAL BIOMEDICS Topical BioMedics is the research and development leader in patented topical natural biomedicines for pain relief.
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I feel like I should explain what happened here.The phone I was using at the time started having issues where the video would become unsync Luckily they are hidden by the hair and they are not a cosmetic problem like those on the face. Zinc Cream for Natural Foods Help Acne Natural Prescribed Medications Problem Skin This fast acting formula to Natural Foods Help Acne Natural Prescribed Medications help clear and Quickly to Prevent acne blemishes skin rashes itching and Other skin irritation. Ricky Martin is known for being a handsome stud in the public eye but did you know his studly icon has rather complicated skin? If you have a problem with excessive blackheads no need to fear because there are many types of blackhead removers on the market today. Rub Natural Foods Help Acne Natural Prescribed Medications this mixture to get rid of blackheads on nose forehead Acne Care Treatment – Make your skin free of acne! Meng devised a way to apply a famous class of chemical reactions to cellulose, a natural polymer often used for drug delivery. Many familiar materials are polymers, including proteins, DNA, and cellulose, a sugar-based polymer which gives plant cell walls their structure.
The polymer eventually swells and releases the drug, allowing it to be absorbed into the bloodstream. With the help of Edgar and John Matson, a chemistry professor in the College of Science, Meng developed a method to successfully modify cellulose using cross-metathesis, overcoming challenges including solubility and the formation of undesirable side products. The spectrum of different polymers available is like "harvesting apples this year, peaches next year, and pears the next yeara€”all from the same tree," he said. The prestigious, annual, international award carries a cash prize and an invitation and funding to speak at the American Chemical Society meeting in San Diego in March, 2016.
Although genital herpes will eventually clear up without treatment, it is much better to start taking a medication which can be used to help reduce both the symptoms and the duration of the infection. It was soon found that the former option was ineffective while the latter course often resulted in the spread of the herpes along the scar which was left after the surgery. Since then it has been found that this medication, if taken on a daily basis can reduce recurrence frequency from approximately four times per annum to about once a year. She has worked in the world of STD's since 1988 and has become a strong advocate for STD education and awareness. Correct treatment has to be given in the early development stages so that no further complications occur which affects not only the sufferer but also the whole family.As soon as the ailment is identified, treatment should begin and there are many types of treatment which is done according to the severity of the problem.
The right doses have to be administered for which frequent monitoring by the doctor is necessary. A therapist can help and guide the patient in the correct way along with the support of the family. Self-help also is a way of treatment as one should try to remove negative thoughts and feelings and to think positively which will help increase self-confidence. The family should be educated about the disease so as to understand the problems and how to deal with them effectively.


You accept that you are following any advice at your own risk and will properly research or consult healthcare professional. Research has shown that women generally experience more recurrent and severe pain than men, yet there is still a lack of awareness about pain issues affecting women. The company's flagship product, Topricinr Pain Relief and Healing Cream, was introduced in 1994 and is now a leading natural therapeutic brand. Users are solely responsible for the facts and accuracy of all information posted and shared on the Site. This disclaimer of liability applies to any damages or injury under any cause of action, including, without limitation, those caused by any failure of performance, error, omission, interruption, deletion, defect, delay in operation or transmission, computer virus or bug, communication line failure, theft, destruction or alteration of or unauthorized access to the Site or materials on the Site. Review the charts find similar foods and use the icons to find food for a healthy lifestyle. Follow these simple but effective steps in order to achieve clear skin using natural products. The cows that give the milk are Aromatherapy essential oils have been used as an application for the skin from times immemorial. Electric black night crash hunger on your face Opium heat rash suffocate this place Well I see the sun burning in your Natural Foods Help Acne Natural Prescribed Medications eye I see the sun call. At Clinique, we believe foundation needs to fit your Skin Type as well as your skin tone to be a perfect match.
If they are taken in a combined format where one product treats the outbreak and actual symptoms of the herpes while the anti-viral meds provide a daily maintenance and preventative treatment, the results have been very successful. Current research is looking for ways to develop a herpes vaccine and this would certainly be a very welcome breakthrough.
ADHD or Attention Deficit Hyperactive Disorder has been included in the common psychiatric disorders for children, which may be caused by genetic influences, upbringing, or emotional uncertainties in a child. It may suppress the symptoms of mania and depression, but needs psychiatric treatment as well and support from the family to overcome the situation.
A combination homeopathic formula, Topricin was awarded a patent for the treatment of pain associated with fibromyalgia and neuropathy. PitchEngine reserves the right to reject or hold social media releases that it deems not newsworthy in its judgment, at any time. Most cases of acne can be cleared including cystic or severe nodular acne though they require the treatment of a dermatologist. Neutrogena Oil Free Acne Face Wash is the #1 dermatologist recommended Its gentle foaming action removes oil, dirt, skin debris and makeup without It is best suited for pimple Acne (59) products I have sensitive acne prone oily skin.
The herbs may be given to a child with ADHD to help him calm down when spikes of hyperactivity occurs.
What you need should be a permanent solution which can stop the acne from appearing in the future and avoid possible scars. The products contain: no parabens, petroleum or harsh chemicals, are odorless, greaseless and non-irritating, and produce no known side effects, making them ideal and safe for the entire family. Or do you smear on the moisturizer to smooth the wrinkles but cope with the zits ought on by the extra oil or sensitivity to a new product? One of the big problems is that infected people can keep on re-infecting themselves either on the skin area itself or from nerve cell to nerve cell and this is why it is so important to take medication to treat the symptoms of the herpes.
So, please, if you like a post here or on any other blog you visit for that matter, take a moment to visit sponsors and to share it with your friends. However, with the mentioned supplements for children with ADHD, it is still important to consult your physician before giving such supplements. Originally a style consultancy ACNE or Ambition to Create Noble Expressions was born when the denim line became a huge hit with clients.
The drug of choice – with potent pharmacologic ingredients – is Ritalin, a known stimulant. Your physician might give you pharmacological drugs such as Ritalin but may also give specific supplements.
However, it has been understood that there are far more natural or calmer versions of the drug.
See how tea Natural Foods Help Acne Natural Prescribed Medications tree oil can help your skin stay healthy and types of pimples under the skin raised scars on back glowing. It is high in omega fatty acid which can help a growing child comply his nutritional needs for optimal growth.
Moreover, there is research that a tremendous decrease in polyunsaturated acids may contribute to ADHD and dyslexia. Moreover, when choosing fish oil, choose one that scores high in omega 3 fatty acids (EPA) and omega 6 fatty acids (DHA). The high ratio of EPA and DHA is proven to be successful to palliate the signs and symptoms of ADHD.
The fast-absorbing cream is odorless and greaseless and is formulated for maximum absorption can be applied many times as needed to relieve pain with no fear of overuse or interference with other medications.



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