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Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. When patients with locally advanced non-small cell lung cancer (NSCLC) received intensity modulated radiation therapy (IMRT), they had less severe lung toxicity and were able to better tolerate their chemotherapy, compared to patients who received conventional radiation therapy, the findings showed.
For decades, three-dimensional conformal radiation therapy (3-D CRT) has been the standard of care for the treatment of lung cancer. The technique shapes radiation beams aimed in straight lines to match the shape of the tumour.
In contrast, IMRT is a newer, more-advanced technique that sculpts and molds radiation beams to tumour targets, using substantially more complex radiation beam arrangements than 3D-CRT.
In turn, IMRT can spare more normal tissue than 3D-CRT with high doses of radiation, Mr Chun explained.


This study is a analysis of data collected from a large, multi-centre phase three randomised trial of patients with locally advanced NSCLC.
In the study, 482 patients were treated with radiation - 53 percent with IMRT and 47 percent with 3-D CRT.
The study found 44 percent fewer cases of severe pneumonitis (lung inflammation that could lead to death) in patients who received IMRT, compared to the 3-D CRT group. The findings were presented at the American Society for Radiation Oncology's 57th annual meeting in San Antonio, Texas. You can restore your account within 30 days by following the link sent to the e-mail address you entered during registration.CloseCommunity standardsThe fact of registration and authorization of users on Sputnik websites via users’ account or accounts on social networks indicates acceptance of these rules. Users are obliged to speak respectfully to the other participants in the discussion, readers and individuals referenced in the posts.


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