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Pernicious anemia (PA) and multiple sclerosis (MS) are both autoimmune disorders that cause fatigue, chronic pain, and physical handicaps, but that is where their similarities end. Without enough vitamin B12 in your system make plenty of healthy blood cells, you wind up feeling constantly tired, unfocused, disoriented, and depressed. Vitamin B12 is also needed to produce myelin, a substance which protects your nerve cells from harm. Gradually, depleted vitamin B12 may cause further irreparable damage to the nervous system, in addition to increased risk for stroke, heart attack, and age-related dementia. Only immediate vitamin B12 supplementation can reverse the symptoms of pernicious anemia, and prevent future relapses. Multiple sclerosis also affects the nervous system, causing severe muscle pain, paralysis, and multiple neurological problems, some of which are similar to those experienced with pernicious anemia, only on a much higher level. While pernicious anemia is easily treated with strict vitamin B12 supplementation, multiple sclerosis is much harder to manage, requiring various medications formulated to relieve specific symptoms.
Scientists aren’t positive exactly what causes multiple sclerosis, but they do know that Caucasian females are the highest risk factor for MS. If you found this article helpful, then please share with your friends, family, and coworkers by email, Facebook, or Google+.
Tags: Multiple sclerosis MS, Nervous system damage, Pernicious anemia (PA), vitamin B12 deficiency, vitamin b12 levels, Vitamin B12 supplementation Posted in Pernicious Anemia- What is it?
Is it possible to get too much of a good thing, like too much vitamin B12, or too much of any vitamin, for that matter?  Experts say yes- overdoing it on certain vitamins can cause vitamin toxicity, and the damage can range from annoying to severe.  So before you down a bottle of vitamin C for immune system health, have a look at what health experts have to say about vitamin B12 and others.
Vitamin B12 (cobalamin) is a water-soluble vitamin that occurs naturally in animal-based foods like beef, chicken, fish, eggs, and milk.  Vitamin B12 supports many vital bodily functions, like shielding your nerve cells through myelin production, maintaining healthy red blood cells, aiding in DNA synthesis, enhancing cognitive functioning, and increasing stamina.
According to the Institute of Medicine’s list of Tolerable Upper Intake Levels, certain vitamins like vitamin B12 are safe to take in mega doses, while other vitamins must be used in moderation.  Taking too much of a certain vitamin may result in stomach discomfort, birth defects, or organ damage, according to many published studies. One clinical study focusing on high-dose vitamin B12 found that taking 2,500-5,000 mcg of vitamin B12 every few days led to a 50%-80% increase in stamina, mental focus, and overall wellbeing after only a few weeks.
In a double-blind crossover study on vitamin B12 for treating tiredness, people who suffered daily fatigue but didn’t have vitamin B12 deficiency or chronic fatigue syndrome (CFS) experienced a boost of stamina, enhanced concentration skills, and improved mood after taking 5,000 mcg of vitamin B12 twice daily for two weeks. Another study on people who didn’t have low vitamin  B12 levels resulted in similar findings with varied doses of vitamin B12, from 3,000 mcg four times per week to 9,000 mcg daily. The upper limit for vitamin A supplementation is 3,000 IU for adult males and females.  Health experts strongly advise meeting your vitamin A requirement through dietary sources like eggs, fortified milk, and liver, as opposed to pill form. The Institute of Medicine recommends taking no more than 100 IU of vitamin D per day, unless you have vitamin D deficiency. The maximum daily dose of vitamin E is 1,000 IU for adult males and females.  Dieticians recommend getting your vitamin E from food sources like wheat germ, sunflower seeds, and broccoli, as opposed to taking vitamin E pills. Know anybody who could be helped by this information?  Please share this article on Facebook, Google+, or by emailing a link.
We love to hear from you…please feel free to leave comments, suggestions, or questions below! The vitamin B12 blood screening is the most important test for diagnosing vitamin B12 deficiency, and if you respond well to vitamin B12 supplements, then further testing is not usually required.
3) Serum folate level:  Many people who have vitamin B12 deficiency also are deficient in the B vitamin folate. 4) Serum  lactate dehydrogenase (LDH): Your doctor might order a blood test measuring LDH levels. 5) Reticulocyte count: This test looks for reticulocytes (slightly immature red blood cells).
6) Homocysteine test:  High homocysteine levels in your blood may indicate vitamin B12 deficiency, folate deficiency, or vitamin B6 deficiency. 7) Gastrin level: a test measuring the amount of the hormone gastrin in your blood may help doctors diagnose the cause of vitamin B12 deficiency. 8) Methylmalonic acid (MMA) test- With vitamin B12 deficiency, methylmalonic acid levels go up.  The MMA test provides more proof of the existence of vitamin B12 deficiency.
10) Bone marrow staining: Sometimes, your physician might require a bone marrow biopsy in order to determine other potential causes of pernicious anemia or general red blood cell disorders.
If B12 deficiency symptoms (fatigue, muscular pain, and brain fog) continue despite vitamin B12 injections, you may supplement with additional over-the-counter (OTC) vitamin B12. Once your vitamin B12 levels are normal, your doctor will likely stop vitamin B12 shots in favor of OTC vitamin B12.
Sublingual vitamin B12 are an OTC option that may require supplementation two or three times per day.  Side effects may include unpleasant taste and burning, tingling sensation on the tongue. Aside from taking the blood test for vitamin B12, have you received any of the other tests mentioned?

If you suffer from Crohn’s disease, then check your vitamin B12 levels often.  One side effect of Crohn’s is pernicious anemia from vitamin B12 deficiency, in addition to Crohn’s symptoms like stomach cramping, diarrhea, and vomiting. Not surprisingly, there are several reasons why vitamin B12 deficiency occurs with Crohn’s disease. Crohn’s disease, sometimes called ileitis, is an illness of the gastrointestinal (GI) tract that damages the bottommost part of the small intestinal, the terminal ileum. The ileum is an important part of your digestive system for vitamin B12 absorption- without it, your body would be unable to extract vitamin B12 (cobalamin) and dispense it into your blood supply.
If Crohn’s disease has caused irreparable inflammation of your terminal ileum, you are at high risk for symptoms of vitamin B12 deficiency.
Once vitamin B12 deficiency is diagnosed, you may choose to take vitamin B12 shots, which are only available upon prescription. These medications often include anti-inflammatory drugs such as mesalamine medicines and immune system suppressors, such as Methotrexate (Rheumatrex). Only vitamin B12 supplements that bypass the digestive system can provide the benefits of vitamin B12. Left untreated, pernicious anemia from B12 deficiency can cause neurological damage, osteoporosis, and in extreme cases, death. Any GI surgery that involves removal or reduction of the ileum results in vitamin B12 deficiency.  In Crohn’s disease, resection surgeries such as ileostomy necessitate lifelong supplementation of prescribed vitamin B12 shots. Similarly, gastric bypass patients can no longer digest vitamin B12 in the stomach, and must get vitamin B12 injections indefinitely. In such cases, many opt for nonprescription OTC vitamin B12 for extra energy and mental stamina between vitamin B12 jabs.
People suffering from IBD (Crohn’s disease, ulcerative colitis) are required to follow restrictive diets excluding many foods that may irritate the digestive system.  Fruits and vegetables that are uncooked may be red flag items, in addition to food sources of vitamin B12, such as meat, poultry, fish, milk, and eggs. Additionally, stomachaches, nausea, and diarrhea make it hard for Crohn’s disease sufferers to eat nutritious, filling meals.  As a result, people with Crohn’s often suffer from excess weight loss and malnourishment. One of the leading types of malnourishment today is pernicious anemia from vitamin B12 deficiency. Please tell us if you have found this article helpful and informative.  As always, we welcome your comments! You might not realize this, but your prescription medications could be giving you vitamin B12 deficiency; certain drugs drain B12 from your system and prevent you from absorbing vitamin B12- cobalamin- naturally from food sources. Vitamin B12 is a water-soluble vitamin that occurs naturally in most animal protein sources; beef, chicken, turkey, fish, shellfish, mussels, eggs, milk, cheese, and yogurt are all rich in this essential B vitamin. However, there are certain conditions, demographics, and lifestyle choices that can inhibit your body’s ability to absorb vitamin B12, regardless of how many hamburgers you eat. TweetShareA study done in Germany demonstrates that pregnant vegetarian women may not have an adequate supply of vitamin B12.
Many pregnant vegetarians are choosing to include eggs and milk in their diets to supply them with vitamin B12, which is necessary for proper nerve formation in the fetus.
A woman who is B12 deficient is at a greater risk during pregnancy for pre-eclampsia and other pregnancy-related complications. The purpose of the study in Germany was just to compare the blood plasma vitamin B12 levels of women who ate a traditional western diet (meat eaters) with women on a vegan diet and ovo-lacto-vegetarian diet.
Over one hundred pregnant women were recruited for the study and divided into three groups: The ovo-lacto-vegetarian group, the low-meat eater group, and the control group.
As far as Body Mass Index (BMI) is concerned, the vegetarians and low-meat eaters had lower pre-pregnancy BMIs than the control group (meat eaters). With regard to B12 concentrations, the vegetarian and low-meat eaters had much lower levels of vitamin B12.
In summary, the study demonstrates that women on vegetarian diets are at greater risk for a B12 deficiency, thus placing their infants at a greater risk for neural tube defects. If you are pregnant and do not eat much meat, it is highly recommended that you supplement your diet with vitamin B12. Reproduction in whole or in part in any form or medium without express written permission is prohibited.
When your child is sick, all you want to do is make them feel better by providing them with effective relief from their cold symptoms. Children under 6 years old can be given single-ingredient pain relievers and fever reducers such as Infants’ and Children’s TYLENOL®. You should only take one medicine with acetaminophen at a time.Use our medicine checker to ensure you are taking medicine responsibly. Stop use and talk to a doctor if your child feels nervous, dizzy or cannot sleep.  Consult a doctor if fever lasts more than 3 days, sore throat pain lasts more than 2 days, or symptoms last more than 5 days.

In Case of Overdose, contact a doctor or Poison Control Centre immediately, even if you do not notice any possible signs or symptoms such as increased sweating, nausea, vomiting, stomach pain, and loss of appetite.
Ok first night was rough, 2nd night was so much better kids were feeling better so I felt better. We bought this for our little one and it did a good job helping to relieve his stuffy, runny nose. Please note that this content is not intended as professional medical or healthcare advice and is not intended as a substitute for professional healthcare advice, or services from a qualified healthcare provider such as a physician, pediatrician or other professional familiar with your unique situation. This site is published by McNeil Consumer Healthcare, division of Johnson & Johnson Inc. By registering, you agree to receive additional communications regarding product information, promotions, newsletters and surveys from our site.
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If that’s the case, why are so many doctors quick to diagnose multiple sclerosis before testing for simple vitamin B12 deficiency from pernicious anemia? Over time, plummeting levels of vitamin B12 cause many debilitating symptoms- muscle pain, numbness, spasms, fatigue- all as a result of diminished red blood cells and impaired neurological functioning. That’s why pernicious anemia symptoms such as chronic pain, numbness, tingling in the arms and legs, and mobility difficulties may reveal a weakened nervous system caused by insufficient vitamin B12 levels.
Scientists believe that MS may be triggered by an infection, which the immune system begins to attack. Scientific evidence suggests that even people who don’t have vitamin B12 deficiency gain enormous health benefits- increased energy and mental alertness- by taking generous doses of vitamin B12. This study was performed at the German Institute of Human Nutritrion in Postdam-Rehbrucke located in Nuthetal, Germany. However, many women are opting to restrict themselves to diets of predominantly plant origin in the belief that this will increase their lifespan and reduce the likelihood of death from heart disease. Hence, their diet is referred to as the “lacto-ovo-vegetarian diet.” This particular study in Germany was done in reaction to other studies that showed that infants born to mothers on strictly vegetarian (vegan) diets were deficient in vitamin B12.
The ovo-lacto-vegetarians were women who never ate meat at all in the three years prior to the study. Children’s TYLENOL® Cold liquid relieves stuffy nose, runny nose, sneezing, fever, and aches and pains. 40, flavour, glycerin, polysorbate 60, propylene glycol, purified water, sodium benzoate, sorbitol, xanthan gum. Utiliser notre verificateur des medicaments pour vous aider a prendre votre medicament en toute securite. If you choose to register with a social provider, certain information will be shared by your social provider with our site. Check your inbox for our welcome email.Thank you for signing up Tylenol newsletter updates.
We have made some changes to our site and we need you to create a new password in order to login. This blog is dedicated to providing up to date research, news and resources pertaining to vitamin B12, general health information surrounding the benefits of vitamin B12.
After fighting off the infection, your body continues to attack, this time mistaking your nerve cells’ myelin- the same substance supported by vitamin B12- as a threat.
A breast-fed infant of such a woman has a greater likelihood for developmental abnormalities and growth failure. Learn from, and contribute to information on B12, vitamin B12 and other connected subjects. So the cycle continues, creating damage to the central nervous system and prolonging debilitating symptoms of multiple sclerosis. Overdose may cause severe or possibly fatal liver damage.  May cause excitability or drowsiness.
Side effects may include: allergic reaction, breathing difficulties, convulsions, drowsiness, hallucinations, and rapid heart rate.

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