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A revolutionary new way of delivering chemotherapy, 1,000 times stronger than normal, offers hope to women battling ovarian cancer. A trial of the new technique, known as intraperitoneal chemotherapy, has just been launched across the UK from Barts and The London School of Medicine.
Hitting the tumour harder could also reduce its ability to become resistant to chemotherapy drugs, a common problem with ovarian cancer.
The PETROC study, a joint UKCanadian trial, will recruit 150 women newly diagnosed with advanced ovarian cancer. Dr Gallagher said: 'Earlier studies indicate that when given directly the platinum-based drug is about 10 times more concentrated and the paclitaxel is about 1,000 times higher than when given intravenously.
During the treatment, a small catheter is inserted into the abdomen during surgery or under local anaesthetic.
Each course of chemotherapy takes around six hours - slightly longer than conventional treatment.
Dr Gallagher hopes this new trial will identify the patients most likely to benefit and resolve any worries about catheters causing pain. Ovarian cancer has been called the 'silent killer', as it is often so advanced by the time it is diagnosed that two out of three women will not survive. Symptoms, which include pelvic and abdominal pain, bloating and difficulty eating, can be confused with Irritable Bowel Syndrome. Professor Iain McNeish, a specialist at Barts and The London Hospital, often sees patients who were initially told they had a gastric rather than gynaecological problem.
He does not blame doctors, as most GPs will only ever see three or four cases of ovarian cancer. But he said: 'For IBS to appear for the first time in a woman in her 50s, or older, is very rare. In most cases, it won't be a tumour, but if it is ovarian cancer, early diagnosis is the key, says Professor McNeish. The views expressed in the contents above are those of our users and do not necessarily reflect the views of MailOnline. Twitter has recently been “dumped” by a few celebrities  – Miley Cyrus, Trent Reznor, Lily Allen and Courtney Love, just to name a few — but, some new stars are joining in to take their place. The feed features behind the scenes photos, sneak peeks at the third film, Eclipse, and exclusive updates on the films’ progress. Twilight’s main stars aren’t on the feed, but they have been all over the headlines as the media follows Lautner’s abs, Pattinson’s love life and Stewart’s lack of one.
Taylor Lautner was the speculation of some plastic surgery improvements after showing off some super-sculpted abs that some experts thought may have been the result of precision liposuction, or abdominal etching. Robert Pattinson has also been the object of speculation after revealing that his modeling career ended after he developed a manlier look at age 16. It was also recently announced that David Beckham would be replaced on the men’s side of Armani by 24-year-old Real Madrid soccer star Cristiano Ronaldo. Victoria Beckham had expressed concern about exposing so much skin while shooting the ads, saying she was self conscious about showing her stomach, which bears the telltale signs of three pregnancies.
A source close to Posh told the UK Daily Express, “She adores the pics but she is extremely critical of her body and finds fault with everything.
Victoria Beckham is well-known for her plastic surgery, and is rumored to have increased her chest size from B to DD with implants, and back down again. But, Megan Fox is no plastic surgery virgin either, and is rumored to have had some facial work done and breast augmentation, according to the experts at In Touch: “Her upper and lower lips appear fuller.
Jon Gosselin may soon be $180,000 short —  if he obeys a Pennsylvania judge and returns the loot. Jon, former co-star of TLC reality show Jon & Kate Plus 8, was recently accused by estranged wife Kate Gosselin of taking $180,000 from their joint bank account after their separation, leaving her with almost nothing. In the meantime, as many know, Kate will carry the show altogether, which set to be re-titled Kate Plus Eight. The show’s new structure occurred in light of Jon leaving the show – a move reportedly in light of falling rating, which were supposedly a result of his alleged infidelities. Dating a girl whose father makes his money through plastic surgery is probably a canny move for Jon Gosselin.
Jon Gosselin, who had reportedly taken $180,000 from a joint account shared with wife Kate, has been ordered to return the money by October 26.
Mad Men star January Jones is hotter than ever on GQ's cover, and recently discussed how she views her current standing in the race for good roles. January Jones recently told GQ that years ago, former boyfriend Ashton Kutcher had doubts about her acting ability.

Her motivation is paying off in spades these days, with her Mad Men role building her a fan base larger than ever. The Mad Men stardom means that Jones, who is now 31, is more visible than ever in paparazzi photos and publicity shoots. But, she did recently share some thoughts with Jack Nicholson – yes, that one – who interviewed her for Interview magazine. She recently complimented Mad Men co-star Christina Hendricks, who is naturally curvy — and recently displayed this, bridal style, in her wedding to actor Geoffrey Arend. Carnie Wilson, who hosts The Newlywed Game, presented the first gay married couple in the show’s history. Carnie Wilson made history of sorts when she played host to The Newlywed Game’s first gay married couple in the show’s 43-year-history. The Newlywed Game, of course, has become a television icon and goes back before host Wilson’s time — it began with presenter Bob Eubanks in 1966. Wilson had gastric bypass surgery in 1999, which spared her of 150 extra lbs., and prevented some health problems, but left her with loose skin. Wilson later posed nude for Playboy to display the results … and later after that, regained some of the weight. In recent years, Carnie Wilson has gotten a lot of her attention by virtue of her appearance – its improvements and setbacks.
Maria Shriver apologizes for breaking a California law that requires drivers to use hands-free units.
When Arnold Schwarzenegger gets peeved and promises swift action, the wise will hide in a tank or flee the country.
Shriver was also examined in her photos for evidence of plastic surgery, but Manhattan surgeon Dr. Shriver's statement did not say whether she would use a hands-free device in the future — and her office had no further comment. Khloe Kardashian and Lamar Odom have been married for three weeks, and still don’t know where they should honeymoon.
There are rumors that the rushed ceremony on September 27 wasn’t real, and that the marriage won’t be official until attorneys for both parties have agreed on the prenup terms. On this episode of Plastic Surgery Talk, aesthetician Karen McCown demonstrates topical products that can make a big difference for fine lines and wrinkles without a big commitment. Zurich University Hospital, the largest hospital in Switzerland, is refusing to treat so-called “medical tourists” from America or Canada who want plastic surgery. Medical tourism in Switzerland has a long history, reportedly going back as far as the 19th century. Ralph Lauren model Filippa Hamilton was digitally retouched for an ad, despite the fact that she is actually underweight. Filippa Hamilton, a 23-year old Ralph Lauren model, had been working for the company since she was 15. In 2007, Spain banned models who weighed less than 120 pounds from walking in Madrid Fashion Week out of concern for women trying too hard to lose weight for the shows. Hamilton said she was “extremely hurt” about the firing, but even more so after digitally retouched images of one of her shoots appeared in a Japanese ad for Lauren’s Blue Label. In the image, she had been retouched so drastically that her head appeared larger than her waist. With her measurements the leggy model definitely doesn’t need liposuction or body sculpting to be thin. When asked if she would sue Ralph Lauren over the photo or the firing, Hamilton said, “I don't think so, but I'm not sure. The anti-cancer drugs are put directly into the abdomen, via a catheter, instead of being injected into the bloodstream using an intravenous drip. It is unusual for it to spread to other parts of the body - in that way, it's different from many other cancers. Because more cancer cells are destroyed in each dose of chemotherapy, there are fewer left with the opportunity to evolve and develop ways of surviving the treatment. It will compare the effect of identical doses of two conventional chemotherapy drugs - paclitaxel plus either carboplatin or cisplatin, which are both forms of platinum - when given directly into the abdomen or intravenously. Just 4 per cent of women are confident they could spot the signs of the disease, according to a poll carried out last week. However, the star was quick to reveal his look was a result of hitting the gym and packing on 30 lbs. Some plastic surgery experts have said he may have had rhinoplasty and jaw implants to give his face the look of a finer bone structure.

The Transformers and Jennifer’s Body star is set to replace Britain's biggest WAG as the face of Armani lingerie. Other sources also claim she had rhinoplasty to narrow her nose, lip augmentation and Botox. And now, a Pennsylvania court has ordered Jon Gosselin to return this amount to the account by October 26, or face contempt charges.
Jon Gosselin’s lawyer Mark Heller told US Magazine on October 11 that his client would “take the high road” and stay quiet about his side of the case. Several sources linked him to shenanigans with family nanny Stephanie Santoro — currently, Jon Gosselin is in an open relationship with Hailey Glassman. Now that she plays Betty Draper on Mad Men, and had memorable turns in We Are Marshall, Love Actually and Anger Management, he has cause to change his mind. She has a small but shapely figure – and frankly doesn’t look like she has had any plastic surgery — or, at least she hasn’t discussed it. One thought was of the modern female image, and how it’s changed since the days of Mad Men’s 1960s setting. In 2008, Hendricks was rumored to have developed some of those curves through breast augmentation. Wilson’s hosting gig for this Game Show Network version began in April 2009, and came after her publicized weight struggles. In 2002, she underwent many plastic surgery procedures – including a breast lift, a tummy tuck and liposuction on her stomach and hips. But, regarding plastic surgery, it’s interesting that though both Schwarzenegger and Shriver are rumored to have had it —  their lips stay tight on the subject. However, an article in Slate called “Plastic Arnold” focused on the couple’s possible plastic surgeries – and even included varying opinions from six plastic surgeons.
Despite not being able to get away, Kardashian says they are enjoying their time as newlyweds. Earlier this year, Khloe claimed dieting and exercise helped her lose around 25 lbs., but experts say it’s more likely that the reality star had lipo since she claims to have lost the 20 lbs. And for eye issues that are more serious or long-lasting, board certified plastic surgeon Dr. And the country’s medical tourist sector is said to be worth nearly a billion dollars a year. But in April, she was fired “as a result of her inability to meet the obligations under her contract” according to a statements from the company.
Most models rely on extreme dieting or just good genes to stay thin for the cameras, rather than having the fat sucked out. But Dr Chris Gallagher, who heads the study in the UK, is confident this advance will show an increase in survival of around 20 per cent. Fox’s ads will hit sometime in January, and the star will also be the face representing the brand’s premium jean line. Jon’s new girl also happens to be the daughter of the plastic surgeon who gave Kate Gosselin her tummy tuck. Arnold Schwarzenegger then apologized for breaking a California law that necessitates hand-free units while driving. Still, Schwarzenegger takes the new cell phone law seriously, and reportedly warned his teenage daughter that “she’ll be taking the bus” if she violates it. They can actually reduce the bone by cutting it or sanding it.” The doctor also suggested the possibility of an eyelift and cosmetic eyelid surgery.
Patrick Sullivan explains what surgical options are available, and when to consider them, to get the most natural results. So, with this new policy, the financial effect of denying certain patients is yet to be seen.
Daniel Yamini speculated that Schwarzenegger has had at least a full face lift, plus maybe more work.
Patrick Sullivan explains the difference between eyelid surgery and a brow lift, describes new techniques for achieving optimal results, and shows how cosmetic surgery around the eyes can take years off your face.
Breasts are mostly fat, and because of the extremely low body fat most models are required to have, there is hardly anything left to give their chest definition.

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