Common drugs that cause tinnitus,please help me with my tinnitus,ear nose and throat doctor for thyroid function - PDF 2016

13.09.2013
A popular drug used to treat heartburn, ulcers and acid reflux that is available without a prescription has been linked to kidney damage and failure, new research has found.
These drugs are called proton pump inhibitors, or PPIs, and you might even have one or two in your medicine cabinet right now. To come to this conclusion, researchers analyzed data from the Department of Veterans Affairs national databases. They identified over 170,000 new users of PPIs and compared them to over 20,000 new users of histamine H2 receptor blockers, another class of drugs used to suppress stomach acid.
And after five years of follow-up, the researchers found the PPI users had a 28 percent increased risk of developing chronic kidney disease and a 96 percent increased risk of developing kidney failure, compared to those taking the alternative drugs. Now, prolonged use of PPIs has been linked to several serious health problems in the past, including nutrient deficiencies, bone-density loss, slight increase in heart attack risk and even dementia. But neither past studies or this most recent research definitively prove that PPIs are the culprits behind these issues.
Still, to be safe, doctors warn people should only use PPIs when they’re medically necessary and for the shortest amount of time possible. As the study notes, about 15 million Americans were prescribed PPIs in 2013, though the number is likely higher because many are available over the counter. Doctors often do not address this when prescribing medicine, despite weight gain being very troubling for the patient.
Benadryl (Diphenhydramine) is an antihistamine, which is used for allergies and as a sleep aid. Alternatives: Ask your doctor about inhaled medications for allergies which are not generally associated with weight gain. The most widely prescribed antidepressants are from a class called SSRIs, or selective serotonin reuptake inhibitors. Alternatives: If you are taking a beta blocker for high blood pressure, discuss other medication options with your doctor. Alternatives: Doctors should prescribe prednisone when there is no option for a less potent drug.


Since weight loss is a primary goal of treating type 2 diabetes, it seems illegal that some of the most commonly used drugs to lower blood sugar can cause significant weight gain. This is not to propose that you should not take a medication if your doctor says it is necessary. And this new study claims those who take them are more likely than people on other heartburn medications to develop chronic kidney disease or kidney failure over a five-year period. Given the amount of patients that traditional doctors must see in a day, it is usually easier (read: quicker) to give a medicine than address the underlying cause. This can be even more frustrating when other options exist that do not cause this nasty side effect. Simply, serotonin is thought to play a role in mood, and brain levels are low in many depressed patients. While it is unclear exactly how these drugs contribute to weight gain, it is likely at least partially related to metabolic slowdown. It is used to treat asthma flares and allergic skin conditions, as well as certain autoimmune diseases and arthritis. If you must take prednisone or any steroid, it is very important to be aware of its ability to increase appetite and watch your calorie intake very carefully. People taking these medications need to be aware of the potential for weight gain and work with a qualified professional to mitigate this side effect as much as possible.
When a patient is diagnosed with diabetes, there is often a frantic rush to get the blood sugar down using any means necessary. But if you are taking a medication that can contribute to weight gain, it helps to know ahead of time and create a plan to attempt to negate some of the weight gain side effect. Association of Prescription H1 Antihistamines Use With Obesity: Results From the National Health and Nutrition Examination Survey. Histamine is a chemical crucial for regulating food intake, causing appetite suppression when it binds to a specific receptor in the brain. One of the ways these drugs work is by slowing down the heart, which decreases exercise capacity.


By giving insulin or insulin releasing agents, sugar is removed from the blood stream and often stored as fat. This is certainly a controversial area where mainstream medicine often differs in opinion from complimentary or alternative medicine. Every doctor told me I needed to take proton pump inhibitors or needed surgical intervention. It may also increase the breakdown of fat.1 When the histamine receptor is blocked, its effect on appetite is decreased, leading to increased food intake and weight gain. Serotonin is also well known to be an appetite suppressant, so it stands to reason that these drugs will help with weight loss. And while prednisone is a catabolic hormone, meaning it causes the breakdown of fat and protein, these effects are more than offset by its appetite stimulating properties. The result is a lower blood sugar but often 10 or more extra pounds of fat, which can then increase medication requirements and cause more fat storage.6 This vicious cycle continues and makes it essentially impossible for many patients to ever get off medication. If you find yourself familiar with the scenario laid out above, educate yourself and find a qualified professional whom you trust to work with.
To make matters worse, excess calories consumed in the setting of elevated corticosteroid levels tend to be preferentially deposited around the middle.
Additionally, aggressive blood sugar lowering effects can often cause hypoglycemia, or too low blood sugar, when must be remedied by eating sugar (Often diabetics will need to eat candy or drink juice to get their blood sugar up.) which causes more fat gain from the extra calories. This paradoxical effect is not completely understood, though likely has to do with the complex interaction between serotonin and other appetite regulating mechanisms.



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