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When you think of risk factors for hearing loss, medications probably aren’t at the top of the list.
It’s possible that pain relievers damage the cochlea, the snail-shaped hearing mechanism in your inner ear. Studies like those I discuss above don’t prove that ibuprofen and acetaminophen cause hearing loss.
Sometimes I get letters from readers who ask why I mention studies that suggest, but don’t prove, that a particular practice may have health risks. Harvard Health Publications is the publishing division of Harvard Medical School, providing the general public with authoritative, trustworthy, and accessible health information. To submit your own health question to Doctor K for consideration in a future column, click here. The contents displayed within this public group(s), such as text, graphics, and other material ("Content") are intended for educational purposes only. If you think you may have a medical emergency, call your healthcare provider or 911 immediately. The information you share, including that which might otherwise be Protected Health Information, to this site is by design open to the public and is not a private, secure service.

In the studies, women who took the pain relievers at least twice a week were more likely to have hearing loss. Other commonly used drugs that can cause hearing loss include certain antibiotics, diuretics, and drugs used to treat erectile dysfunction. Always try to take the lowest possible dose for the shortest amount of time to minimize the risk of side effects. My answer is that I generally don’t mention such studies unless I think they are particularly strong scientifically. Anthony Komaroff is a practicing physician, Professor of Medicine at Harvard Medical School, and Editor in Chief of Harvard Health Publications.
The Content is not intended to substitute for professional medical advice, diagnosis, or treatment. Any mention of products or services is not meant as a guarantee, endorsement, or recommendation of the products, services, or companies.
Sharon Curhan, instructor in medicine at Harvard Medical School, explained that ibuprofen can reduce blood flow to the cochlea.
Always seek the advice of your healthcare provider with any questions you may have regarding your medical condition.

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Longer courses of prescription drugs (high-dose ibuprofen) would seem to be more likely to lead to permanent changes in hearing.

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