Use of the substance in the United States has been debated for more than three decades, so Ms. The renewed debate, which has brought attention to the arcane world of additive regulation, comes as consumers show increasing interest in food ingredients and have new tools to learn about them. And the debate over BVO is just the latest of several controversies surrounding the chemical content of other beverages, in which energy drinks have been tied to more than a dozen deaths, and sugary drinks conclusively linked to obesity.

Although evidence suggests serious effects of BVO may not occur unless consumed in very large quantities, its use points to larger issues concerning the way food is regulated in the United States. But the European Union has long banned the substance from foods, requiring use of other ingredients.
Serious loopholes in laws and regulations allow thousands of additives into food without any oversight from the FDA.

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