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The pathway will stop at the point of the missing enzyme, and the amount of an intermediate product will accumulate.
The two enzymes adjacent to the missing enzyme will take over its duties and keep the metabolic pathway going.
Water readily causes polar substances to come apart, making it an excellent biological solvent.

When salt crystals are placed in water, the sodium and chloride ions cannot reform salt crystals. Water molecules form hydration spheres surrounding and separating the sodium and chloride ions.
In water, the ionic charges are reversed, so the sodium and chloride ions repel each other. Sometimes a person develops partial blindness in both eyes when only one visual cortex has been damaged.

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