A new study done with mice has discovered that supplements of lipoic acid can inhibit formation of arterial lesions, lower triglycerides, and reduce blood vessel inflammation and weight gain 0151 all key issues for addressing cardiovascular disease. Although the results cannot be directly extrapolated beyond the laboratory, researchers report that a€?they strongly suggest that lipoic acid supplementation may be useful as an inexpensive but effective intervention strategy . The study found that lipoic acid supplements reduced atherosclerotic lesion formation in two types of mice that are widely used to study cardiovascular disease, by 55 percent and 40 percent, respectively.


The amounts used in this research would not be obtainable by any normal diet, researchers said, and for human consumption might equate to supplements of about 2,000 milligrams per day. Even at low, normal, dietary levels, the compound can play a key role in energy metabolism. Also of considerable interest, Frei said, is the apparent role of lipoic acid supplementation in reducing weight gain.


Weight gain and obesity is a major risk factor for atherosclerosis and heart disease, and lower weight and abdominal fat may be one of the mechanisms by which lipoic acid has beneficial effects, Frei said.



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