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Lebera€™s Hereditary Optic Neuropathy (LHON) symptoms usually begin as sudden, painless loss of central vision. A brief, basic medical overview of LHON is provided in this video by another US LHON Expert, Dr. About 100 people in the United States lose central vision due to LHON each year, joining the 4,000 or so Americans who are already vision impaired due to LHON. LHON is a genetic disorder that can cause the optic nerve to atrophy but does not always do so. Because there is a clear pattern of LHON inheritance, those with a family member on the maternal inheritance chain with LHON should expect that any sudden, painless central vision loss is caused by LHON. Those who are not aware of any family members with LHON are taken by surprise when they suddenly lose central vision. It is important to find a medical professional who is aware of the most current research regarding LHON, as there has been much new learning in recent years and the condition is so rare that most medical professionals are not up-to-date on recent developments.
Another option is to use the Register tab above, and request a referral to an experienced LHON doctor. Since LHON is a rare disorder, it may be helpful to discuss these reports with your ophthalmologist, neuro-ophthalmologist or other health professional to determine if this supplement may be right for you, as well as possible side effects. Many LHON specialists suggest that people carrying a LHON mutation, both carriers and affecteds, should avoid environmental factors that could create additional stress on the mitochondria. Having a discussion with your own LHON medical professional about these factors is encouraged. It is important to avoid getting caught up in the hype of for-profit organizations located in China and other countries who offer a€?stem cell treatmentsa€? to a€?curea€? LHON and other disorders. Making new RCGa€™s means nothing if they dona€™t know where their axons need to connect to. This website should be considered general information only and should not be considered medical guidance or professional advice.
3.Making new RCGa€™s means nothing if they dona€™t know where their axons need to connect to. The signs and symptoms of a brain tumor vary greatly and depend on the brain tumor's size, location and rate of growth. Primary brain tumors originate in the brain or close to it, such as in the brain-covering membranes (meninges), cranial nerves, pituitary gland or pineal gland.
Primary brain tumors are much less common than are secondary brain tumors, in which cancer begins elsewhere and spreads to the brain. Secondary (metastatic) brain tumors are tumors that result from cancer that starts elsewhere in your body and then spreads (metastasizes) to your brain. Though doctors aren't sure what causes the genetic mutations that can lead to primary brain tumors, they've identified factors that may increase your risk of a brain tumor.
More-common forms of radiation, such as electromagnetic fields from power lines and radiofrequency radiation from cell phones and microwave ovens, have not been conclusively linked to brain tumors. The biopsy sample is then viewed under a microscope to determine if it is cancerous or benign. A brain tumor can cause complications depending on the part of your brain that's affected. Treatment for a brain tumor depends on the type, size and location of the tumor, as well as your overall health and your preferences. If the brain tumor is located in a place that makes it accessible for an operation, your surgeon will work to remove as much of your brain tumor as possible.
Radiation therapy uses beams of high-energy particles, such as X-rays, to kill tumor cells. External beam radiation can focus just on the area of your brain where the tumor is located, or it can be applied to your entire brain (whole brain radiation). Side effects of radiation therapy will depend on the type and dose of radiation you receive.
Radiosurgery may be an option if your brain tumor can't be removed with traditional surgery. Clinical trials are studies of the latest treatments, such as new drugs or new ways of using existing drugs and new surgical techniques. Because brain tumors can develop in parts of the brain that control motor skills, speech, vision and thinking, rehabilitation may be a necessary part of recovery. Specialists in speech difficulties (speech pathologists) are just one of many types of therapists who can help you recover.
School-age children with brain tumors may especially benefit from tutoring as a part of their overall treatment plan. Some people with brain tumors turn to complementary and alternative medicine treatments to help manage symptoms, improve mood and reduce stress.
A range of dietary supplements and herbal medicines claim to offer new ways to prevent or treat diseases in general. Natural remedies that lower inflammation can also be very beneficial; when indicated they may be preferred over some medications that have adverse effects with prolonged usage. Tumeric is a spice that comes from the root Curcuma longa, a member of the ginger family, Zingaberaceae. Xanthones, which are unique to the mangosteen, as a class of phytonutrients are polyphenolic bioflavonoids.
When indicated; mangosteen juice, consumed daily, may be preferred over some medications that have adverse effects with prolonged usage.
Recent Invivo studies have demonstrated cytotoxic properties against three human cancer cell lines. In some cases, people using mangosteen for the first time may experience a healing crisis or detoxifying effect {an increase or outbreak of symtoms that may last from 4 to 10 days} in the earliest stages of use. Mangosteen juice from the whole fruit puree consumed daily, has successfully been used to treat inflammatory conditions and has demonstrated numerous additional benefits over other natural products. Because it's not always easy to tell which products may be unsafe, interact negatively with other medications or affect your overall cancer treatment, it's best to talk with your doctor before you take any dietary or herbal product. Although there are some common signs of brain tumor such as headache, seizures, nausea or vomiting, memory problems and changes in personality, the exact signs vary from person to person depending on the size, location and type of the brain tumor.


The sudden changes in the normal flow of electricity trigger convulsions or jerking and twitching of the legs and arms. The growing tumor may press on the optic nerve or the optic nerve may swell due to increase in the intracranial pressure following obstruction in the normal circulation of the fluid in the brain, leading to vision problems. Muscle weakness that occurs when the tumor grows in the brain stem or cerebellum or invades these areas causes difficulty in walking.
The tumor and the increase in fluid pressure induced by the growing tumor may compress and damage the delicate brain tissues, resulting in numbness or paralysis of certain muscles of the body.
The classic pattern is for one eye to suddenly lose central vision, then on average 8 weeks later the other eye also loses central vision, though many variations on this pattern are possible. People who have been exposed to a type of radiation called ionizing radiation have an increased risk of brain tumor. People working in certain industries have an increased risk of brain tumors, possibly because of the chemicals they're exposed to on the job.
A small portion of brain tumors occur in people with a family history of brain tumors or a family history of genetic syndromes that increase the risk of brain tumors.
These may include headaches that progressively worsen, are particularly severe, are always in the same location or are accompanied by nausea or vomiting or by blurred or double vision.
A neurological exam may include, among other things, checking your vision, hearing, balance, coordination and reflexes. If it's suspected that your brain tumor may be a result of cancer that has spread from another area of your body, your doctor may recommend tests and procedures to determine where the cancer originated. A biopsy can be performed as part of an operation to remove the brain tumor, or a biopsy can be performed using a needle. A brain tumor that damages the nerves that connect to the eyes or the part of the brain that processes visual information (visual cortex) can lead to vision problems, such as double vision or a reduced field of vision.
Tumors in certain areas of the brain may cause personality changes or changes in behavior.
Brain tumors that affect the auditory nerves {especially acoustic neuromas} may cause hearing loss in the ear on the involved side of the brain. In some cases, tumors are small and easy to separate from surrounding brain tissue, which makes complete surgical removal possible. Radiation therapy can come from a machine outside your body (external beam radiation), or, in very rare cases, radiation can be placed inside your body close to your brain tumor (brachytherapy). Whole brain radiation is sometimes used after surgery to kill tumor cells that might have been left behind. Instead, radiosurgery uses multiple beams of radiation to give a highly focused form of radiation treatment to kill the tumor cells in a very small area. Radiosurgery is typically done in one treatment, and in most cases you can go home the same day. Chemotherapy drugs can be taken orally or injected into a vein (intravenously) so that they travel throughout your body. When removing all or part of the brain tumor, your surgeon may place one or more disk-shaped wafers in the void left by the tumor. This drug, given through a vein (intravenously), stops the formation of new blood vessels, cutting off blood supply to a tumor and killing the tumor cells. Together you can discuss the benefits and risks and decide if a trial is appropriate for you. The brain can sometimes heal itself after trauma from or treatment of a brain tumor; but this can take time and patience. These treatments may include prayer or spiritual healing, meditation, and vitamin and herbal supplements. Even over-the-counter or so-called natural supplements may interfere with your prescribed medications. Although long-term use of NSAIDs in high doses can provide great benefit in terms of anti-inflammatory effects, pain relief and cardioprotective effects, there is an increased risk of gastrointestinal complications ranging from stomach pain to ulcers, hemorrhage, and severe and potentially deadly gastrointestinal problems. Cur cumin has historically been safely used in Ayurveda for its medicinal properties for various indications. Mangosteen has been demonstrated to exhibit potent anti-inflammatory and anti-tumor properties.
The flow cytometric analysis indicated that this compound induced apoptosis in time-and concentration-dependent manners.
Once the body is cleared of the toxins that exasperate the condition, the healing process can get underway.
More mangosteen research is needed, but current scientific studies have demonstrated promising results in regards to benefiting patients with cancer. Also known as creosote bush or greasewood, chaparral (Larrea tridentata) comes from a desert shrub found in the southwestern United States and Mexico. This mixture contains eight herbs that have been used for hundreds of years in traditional Chinese medicine to treat prostate issues and other health problems.
Shark cartilage contains a protein that has some ability to inhibit the formation of new blood vessels within tumors in sharks. In about a third of brain tumor patients, seizure is the first noticeable symptom of the ailment.
Double vision, blurry vision, loss of peripheral vision and in the worse case blindness can occur if the brain tumor is left untreated.
Memory problems, especially loss in short-term memory, communication and speech problems, behavioral changes and cognitive impairment occur when specific areas of the brain are damaged by the tumor.Behavioral changes usually develop when the tumor is located in the cerebral hemispheres and corpus callosum. Diabetes insipidus, breast enlargement, vision changes and headache may be triggered by abnormal changes in the levels of hormones secreted by the pituitary gland.
Valerio Carelli made very informative presentations about the LHON clinical profile and therapeutic options.
Valerio Carelli made very informative presentations about the LHON clinical profile and therapeutic options.A  Click on the photos below to watch their presentations. Asian countries,[18] United States (including Hawaii), Canada ,[19] and Scotland)[20] due to bacterial resistance. Some brain tumors are noncancerous (benign), and some brain tumors are cancerous (malignant).


In other cases, a brain tumor is the first sign of cancer that began elsewhere in your body. Examples of ionizing radiation include radiation therapy used to treat cancer and radiation exposure caused by atomic bombs. Studies don't always agree, but there is some evidence of an increased risk of brain tumor in certain industries, including agricultural, electrical, health care and oil refineries.
Difficulty in one or more areas may provide clues about the part of your brain that could be affected by a brain tumor. A stereotactic needle biopsy may be done for brain tumors in hard to reach areas or very sensitive areas within your brain that might be damaged by a more extensive operation. But if the part of the brain involved happens to control strength or movement of an arm or leg, it could produce definite weakness in that part of the body. These headaches can be severe and unrelenting and may be accompanied by nausea and vomiting.
In other cases, tumors are located near sensitive areas in your brain, making surgery risky.
For instance, surgery on a tumor near nerves that connect to your eyes may carry a risk of vision loss.
Whole brain radiation may also be an option if you have several brain tumors that can't be removed through surgery. Each beam of radiation isn't particularly powerful, but the point where all the beams meet {at the brain tumor} receives a very large dose of radiation to kill the tumor cells. Chemotherapy drugs can also be administered into your spinal column, so treatment affects only your central nervous system. Many targeted drug therapies are very new and still undergoing careful study in clinical trials. The earlier these problems are identified, the earlier they can be addressed with strategies that provide the most benefits to the child. But you can take steps to cope with the shock and grief that may come after your diagnosis.
As your doctor answers your questions, take notes or ask a family member to come along to appointments and take notes.
But the benefits and risks of many products and practices remain unproved in human clinical trials. There have been many cases {based on patients test results} where doctors have reduced or stopped medications due to the benificial effects from natural health products.
When purchasing a health product; look for information that may be found in small print that would indicate drug interactions or product warnings.
Each year in the US, the side effects of long-term NSAID use cause nearly 103,000 hospitalizations and 16,500 deaths. Natural remedies that lower inflammation can be very beneficial in the prevention or treatment of disease.
Alpha-mangostin (One of the many xanthones found in the pericarp of the mangosteen fruit} showed the features of the mitochondrial apoptotic pathway such as mitochondrial membrane depolarization and cytochrome c release.
Shark cartilage therapy is based on the theory that capsules containing shark cartilage will do the same in humans; stop and shrink cancerous tumors. In several cases, the headache improves gradually during the day and returns in the following morning. The rising pressure in the skull or the edema of the brain may lead to gradual loss of hearing. Brain tumors can begin in your brain (primary brain tumors), or cancer can begin in other parts of your body and spread to your brain (secondary, or metastatic brain tumors). Headaches can be due to the tumor itself, or they can result from fluid building up in the brain (hydrocephalus). The more you and your family know and understand about each aspect of your care, the more confident you'll feel when it comes time to make treatment decisions. Several studies were identified on the antioxidant, anti-inflammatory, antiviral, and antifungal properties of curcuminoids.
It has been suggested by the American Cancer Society that mangosteen juice can be used as an effective adjunct with standard cancer therapies to reduce many of the side effects and helps to speed up recovery.
Furthermore, alpha-mangostin inhibited the sarco(endo)plasmic reticulum Ca(2+)-ATPase markedly. Results will vary with individuals but the long term benefits are well worth the short term discomfort as mangosteen juice has been effective with many types of cancer. It was sold as a dietary supplement, but is no longer being manufactured because some batches were found to contain prescription drug ingredients.
A number of specialized MRI scans may help your doctor in evaluation and treatment planning, including functional MRI, perfusion MRI and magnetic resonance spectroscopy.
Even removing a portion of the brain tumor may help reduce signs and symptoms you experience. While the individual herbs are still available, the PC-SPES mixture has not been reintroduced because further studies are needed to determine whether it's safe. And certain types of brain tumors, such as medulloblastomas, occur almost exclusively in children. Tissue is removed using the needle, which is frequently guided by computerized tomography (CT) or MRI scanning.
Reduce stress in your life by taking time for relaxing activities, such as listening to music or writing in a journal.
Online message boards, such as those offered by the National Brain Tumor Foundation, are another option.



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