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Over-the-counter pain relief medications are usually the first line treatment for arthritis pain. Despite the effectiveness of these drugs, certain precautions should be taken while using them. Acetylsalicylic acid, commonly known as aspirin, is the conventional pain relief drug widely used for alleviating arthritis pain.
While short-term use of ibuprofen is considered safe, prolonged intake may increase the risk of stroke and heart attack.
Over-the-counter naproxen sodium is another non-steroidal anti-inflammatory medication used for healing arthritis pain. However, the anti-inflammatory effect of acetaminophen is usually not as powerful as that of aspirin and other non-steroidal anti-inflammatory drugs.

You should avoid or limit alcohol intake to less than three drinks a day while taking ibuprofen. Acetaminophen is a safer alternative to aspirin for people prone to bleeding problems or stomach upset.
Common over-the-counter medications recommended for treating arthritis pain include non-steroidal anti-inflammatory drugs and acetaminophen or paracetamol. Aspirin is not recommended for people who have more than three alcoholic drinks per day as it increases the risk of gastrointestinal bleeding and stomach upset.
People diagnosed with heart, liver or kidney diseases, asthma, stomach problems and hypertension should consult their physicians before taking ibuprofen.
People on acetaminophen should limit alcohol intake to three drinks a day to avoid liver damage.

It works by inhibiting the activities of the pro inflammatory COX enzymes that trigger inflammation and pain. Serious side effects of aspirin that require prompt medical intervention include easy bruising, excessive bleeding, tinnitus, hearing difficulty, fatigue, nausea, vomiting and allergic reactions such as breathing difficulty, hives and facial swelling. People suffering from liver or kidney disease should take this drug under medical supervision. Side effects such as constipation, stomach upset, bloating, gas, ringing in the ears and nervousness, although rare, may occur following ibuprofen intake.

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