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Florida Hospital for Children and Cord Blood Registry® (CBR) are launching a FDA-regulated, Phase I safety study of the use of cord blood stem cells to treat children with sensorineural hearing loss.
The study will enroll 10 children between the ages of 6 weeks and 6 years old, who meet the inclusion criteria for the study. Ultimate use of newborn stem cells will be determined by the treating physician who will consider if they are applicable for the condition and should come from the patient or a suitable donor (siblings of the same biological parents have a 25% chance of being a perfect match and a 50% chance of being a partial match; biological parents will always be a partial match). Wearing hearing aids has been such a positive experience for Marie Redfern, she wants to encourage others with hearing loss to try them, too. Your experience can provide helpful information to someone looking for a great hearing care provider, reward a clinic for taking good care of their patients and create a sense of community where you live. That's the impetus behind a study using umbilical cord blood to treat hearing loss in children.
Although hearing aids and cochlear implants are effective means of treating sensorineural hearing loss in both children and adults, these instruments do not repair damaged hearing. Researchers learned the benefits of using cord blood in 1988 when the first sibling-donor cord blood transplant was performed for a five-year-old child with Fanconi anemia. Cord blood stem cells have documented success in treating leukemia, Multiple Sclerosis, Rheumatoid Arthritis, Hodgkins disease and Non-Hodgkins lymphoma to name a few. Although cord blood stem cells have the same capacity as stem cells found in other parts of the body, there is less of a risk for transmitting infectious disease or being rejected by the host.
Cord blood stem cells are different from the controversial embryonic stem cells, which require the destruction of a human embryo to obtain.


Parents must make the decision to collect and store their baby's newborn stem cells immediately after birth. Prevalence of hearing loss among children 6 to 19 years of age: the Third National Health and Nutrition Examination Survey. Founded in 1992, CBR is entrusted by parents with storing samples from more than 500,000 children.
Florida Hospital for Children and Cord Blood Registry (CBR) are launching a FDA-regulated, Phase 1 safety study of the use of cord blood stem cells to treat children with sensorineural hearing loss.
Ten children between the ages of 6 weeks and 6 years old will be treated using their own stored umbilical cord blood. Children with sensorineural hearing loss experience problems or deformities with the cochlea (sensory) or the hearing nerve (neural) due to illness, birth defects, medication, noise or head trauma. If successful, cord blood stem cell treatment could repair the damage, leading to improved speech and language skills, social interaction, and cognitive learning abilities for children with acquired sensorineural hearing loss.
Currently, the company participates in FDA-regulated clinical trials for autism, cerebral palsy, pediatric stroke and traumatic brain injury. Researchers are hopeful cord blood will eventually be effective in the treatment of AIDS, heart disease, Alzheimer's, Parkinson's disease, spinal cord injury and stroke. Stem cells are considered the body's "master cells" because they have the ability to create the different types of cells that make up human organs, blood, tissue and immune system.
Cord blood is collected with no risk to the mother or child and can be frozen and stored for many years. After the umbilical cord has been clamped and cut, the remaining blood in the umbilical cord is drawn into a collection bag.
To ensure consistency in cord blood stem cell quality, CBR is the only family stem cell bank providing units from clients for the study.


CBR is dedicated to advancing the clinical application of cord blood and cord tissue stem cells by partnering with institutions to establish FDA-regulated clinical trials for conditions that have no cure today.
Patients will receive one intravenous infusion of their own umbilical cord blood stem cells and return for follow-up at one month, six months and one year post-treatment. By 2005, clinical trials were in place to investigate newborn stem cell therapies for damaged tissue. Stem cells, typically found in bone marrow and fat tissue, have the ability to divide and develop into any of the three main types of cells found in the blood: red blood cells, white blood cells and platelets. Acquired sensorineural hearing loss results from damage to hair cells in the inner ear (cochlea) and can be caused by illness, medication, noise exposure, birth injury, or head trauma. But what happens if that child is born with a more severe problem – such as a heart defect or hearing loss?
Today, more than one million people have benefited from stem cell treatment for more than 80 different diseases.
As amazing as the human body can be, sometimes its natural healing process needs a little help to get started.
The American Academy of Pediatrics encourages public cord-blood donations; however, opposes private banking in most cases.



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