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Herpes zoster, the virus that causes chicken pox and shingles, can infect the fifth cranial nerve, causing ocular manifestations (corneal inflammation and intense pain) and facial shingles. Herpes simplex, the virus that causes oral and genital herpes, can also infect the eye, causing herpes keratitis, which is also an ophthalmic emergency. A blog for all biological and medical ephemera, from the age of Abraham through the era of medical quackery and cure-all nostrums. Biomedical Ephemera by Arallyn is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. A variety of diseases caused by viruses in the Herpesveridae family fall under the name herpes. Herpes simplex virus (HSV) I and II are responsible for oral and genital infections, with HSV-I more likely to cause orofacial symptoms and HSV-II more likely to cause genital symptoms. Varicella zoster virus (VZV) causes chickenpox and shingles, and it is also called herpes zoster.
Cytomegalovirus (CMV) causes symptoms similar to infectious mononucleosis, and is spread through bodily fluids. I'm always surprised when I remember just how many different kinds of herpes viruses there are. Herpes zoster (widely known as shingles) is a painful viral disease caused by chickenpox virus (varicella zoster virus). If a person has had chickenpox, he cannot be infected with herpes zoster virus, because it remains in his organism all life long. The severe pain continues for 3-5 days, and then it is followed by small red rash that appears on the skin. Herpes zoster may sometimes lead to a post-herpetic neuralgia, the most common complication of this disease. Taking into account complications mentioned above, it is not difficult to realize the importance of shingles prevention and treatment. The Orthomyxoviridae are a family of RNA viruses that includes  Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. Varicella Zoster Virus (VZV) is one of eight herpes viruses known to infect humans (and other vertebrates). Ophthalmologists are in a good position to protect patients at risk for herpes zoster ophthalmicus.
Varicella zoster virus, also classified as human herpes virus 3, is the etiologic cause of two very common diseases, varicella (chickenpox), which affects more than 90 percent of the population by adolescence (and almost 100 percent by age 60); and herpes zoster (shingles) which is experienced by about 30 percent of the population and becomes increasingly virulent as patients age. In this month's article, we'll take a look at the herpes virus and its vaccine, and how ophthalmologists can play an important role in protecting patients from the associated disease.
Like herpes simplex virus, varicella zoster virus grows and spreads rapidly, and has the ability to infect and destroy a number of host cells. The greatest risk factor for herpes zoster is immune status which, incidentally, deteriorates with age.
Classic herpes zoster presents as an acute, often painful, vesicular eruption and is associated with fever, malaise and headache. Even decades after HZO infection, the eye and adnexal tissue never return to their original state. Early use of systemic steroids may impede development by thwarting scarring, but post-herpetic neuralgia is another potential outcome. Patients who develop HZO should be referred to an ophthalmologist, as vigorous antiviral treatment can prevent corneal involvement if initiated within 72 hours of symptom onset.
Antiviral therapy should be initiated at the first sign of HZO infection to avoid serious complications. Experience with the varicella vaccine for chickenpox (Varivax, Merck) provides an interesting context in which to consider VZV. However, the lower incidence of wild-type varicella outbreaks has had negative consequences for adults. Furthermore, global epidemiological data suggest that the ideal age for HZ vaccination may be closer to 50 to 55 years,1,10 though further studies must be performed to verify this hypothesis. Medicare Part D covers some of the cost of the Zostavax vaccine, and private insurance companies vary in their coverage. Surveys were conducted among patients eligible for the vaccine to investigate the reason for such low vaccination rates. Ophthalmologists regularly provide care to the aging population at risk for developing herpes zoster ophthalmicus, and are well aware of the potential severity of the disease. When one considers the relative frequency of HZO and its potential for debilitating pain and dramatic decrease in vision, vaccination is a worthwhile consideration for ophthalmologists.
It’s considered an ophthalmic emergency, as permanent damage can be caused to the ocular nerve and eyeball. Both eye infections can cause scarring along the visual axis, and permanent vision impairment, and generally have to be treated with antiviral pills and eyedrops.


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It is treated with an immunoglobulin injection, sometimes in combination with an antiviral. I don't have any kids, but I have heard that now the Varicella vaccine is given to everyone just like the vaccines for mumps and whooping cough. Maybe it is a regional thing, but where I am from a lot of people call them fever blisters instead of cold sores.
I knew it was a virus, but didn't know it was related to things like cold sores. I agree with you about herpes having a bad connotation.
It seems like all the herpes viruses really aren't all that different! That being said, it is really scary that any herpes virus, from herpes type 1 to chicken pox, stays in your system forever. I always thought the biggest thing with any kind of herpes was the rash, but it sounds like there are a lot of other possible symptoms too! A lot of people don't even know that that chicken pox is related to the same virus that causes an STD.Honestly, I think STDs are still very stigmatized, although they are common. The only kind I feel like I hear about frequently is STD herpes, but as the article said, there are actually eight different kinds of herpes!
At the same time, the virus can be transmitted from the infected person to those who have not had chickenpox and this may lead to the development of chickenpox, but not shingles.
In certain cases, however, if not properly treated, shingles may result in severe complications. You will find all the possible questions on medications, their action, and side effects in this quiz. The first three have viruses that cause influenza in vertebrates (like birds, humans, and other mammals).
It  causes chicken-pox in children and shingles in adults (and sometimes - but rarely - children). Immunity to VZV is dependent upon primary infection or exposure at a young age and subsequent, periodic re-exposure to the virus.1 This often occurs through contact with children during varicella outbreaks, subclinical reactivation of endogenous latent virus, or a combination. Occasionally, it may be associated with transient mood changes, depression and insomnia.6 The prevalence of HZ does not differ by gender, nor is there any seasonal association with the disease. The most serious complication is herpes zoster ophthalmicus, which occurs in 10 to 20 percent of pa-tients with HZ.6 HZO is characterized by a unilateral skin rash in the distribution of the first branch of the trigeminal nerve. One side of a patient's hairline tends to retain sensations of hypoesthesia, and patients live with effects such as decreased ocular sensation forever. PHN is a painful condition affecting the nerves and skin, and is thought to arise as a result of the virus's proclivity for residing in nerves. One study in immunocompetent pa--tients found that 63 percent developed inflammatory reactions in the affected eye, but that their final visual outcome was acceptable. The three oral antiviral agents approved for treatment of HZO in immunocompetent patients are acyclovir, famciclovir and valacyclovir. By the year 2000, vaccine coverage of this typically innocuous disease reached over two-thirds of 18- to 35-month-olds, and there has been no evidence of increasing disease rates in older children in the past decade. Fewer exogenous exposures to the virus by adults living or coming into contact with children have increased the incidence of HZ among adults under 50 years of age, whose cell-mediated immunity (CMI) used to be "boosted" by these exposures.6 Therefore, the incidence of HZ in the elderly is expected to rise.
The Centers for Disease Control and Prevention approximates the cost of the vaccine to be about $150.2 Despite its relatively low cost and widespread availability, as of 2007 only 2 percent of the eligible population (persons over age 60) had re-ceived the vaccine.
Surprisingly, a full 73 percent of respondents had not even heard of the vaccine, though 78 percent said they would get vaccinated if their doctor recommended that they do so.1 These results suggest that there's an opportunity for physicians, especially ophthalmologists, to educate patients about this option and encourage their participation in vaccination programs. Ophthalmologists are therefore in an excellent position to administer this vaccine to eligible patients who are at high risk of developing HZO.
Abelson, an associate clinical professor of ophthalmology at Harvard Medical School and senior clinical scientist at Schepens Eye Research Institute, consults in ophthalmic pharmaceuticals. I could never catch it, though. Now that I am older, I have to get the Varicella vaccine, since chicken pox as an adult can easily turn into shingles, which is much more serious. I would have to assume that that name came about because people in the past linked fevers to those sores showing up shortly after. I used to get cold sores a lot, but I haven't had one for several years now that I think about it. Obviously, some people understand that there can be different types of herpes viruses that cause completely different things. So if you had chicken pox as a child, you're always at risk for developing shingles, because the virus is still in your system. I wonder why people who get genital herpes don't get a fever like some of the other kinds cause? So that's probably why you rarely hear anyone call chicken pox and shingles "herpes zoster" or hear anyone refer to a cold sore as the herpes virus.
Also, your thoughts on herpes transmission is right on as well in that it can be transferred through kissing.
Are there ANY herpes symptoms that have developed after you quit eating pork - even remotely?


I used to always get them after kissing my husband which is where I believe I contracted it. Its reactivation may be caused by emotional stress, aging processes, and weak immune system; so people at the age of 50 and older as well as those having cancer, leukemia, lymphoma, and AIDS, are the most prone to this disease.
It is more dangerous and may have severe complications as the viruses destroy all the levels of the nervous system. To prevent the shingles, doctors recommend avoiding contact with herpes infected people, especially if one?s immune system is suppressed. Some types can cause warts, while some (even rarer) types can lead to cancer in the genitals. During re-exposure to the virus, helper T cells carry immunologic memory and stimulate B cells to synthesize antibody at any sign of VZV provocation, thereby "teaching" new generations of leukocytes to recognize the virus and arm with the appropriate de--fense. As mentioned above, the underlying immune status of the patient is, however, the most important factor. Only herpes zoster, herpes simplex and leprosy cause a decrease in corneal sensation, so this and hypoesthesia can be used to retrospectively diagnose previous HZO. Thus, many people continue to experience nerve-associated pain even after the visible symptoms of HZ have subsided.
Decreases in best-corrected visual acuity, affecting 23 percent of patients at one month, were only experienced by 10 percent of patients at a six-month follow-up.7 Functional vision may therefore be retained in HZO patients, provided they receive the proper treatment following diagnosis. It is indicated for all immunocompetent persons aged 60 and older and the sooner the vaccination is administered, the better the chances of being protected against shingles. Herpes zoster (shingles) vaccine guidelines for immunosuppressed patients.American College of Rheumatology Hotline 2008. Herpes zoster ophthalmicus: Natural history, risk factors, clinical presentation, and morbidity. Safety and immunogenicity profile of concomitant administration of ZOSTAVAX and inactivated influenza vaccine in adults aged 50 and older. I tend to think that since chicken pox isn't normally serious that kids should just be forced to get it like in the past. I would much rather my child have to deal with some discomfort as a kid rather than have to get shots for the rest of their life and risk getting shingles.
Luckily, the vaccine lasts for 10 years, so it's not like it's a huge pain to deal with over the course of my life. On the other hand, you have some people that hear herpes and automatically assume they are all the same and that someone with a cold sore also has and STD.
No one wants to admit to having any kind of herpes for fear of being labeled "dirty" or something.
It has been proved that continuous and uncontrolled stress to the skin (punching, biting, and scratching in the most sensitive areas) may cause herpes zoster too. Trunk and buttocks are the most common places for shingles, but the virus can also appear on the legs, arms, and face. In traditional medicine, herpes zoster is treated with anti-viral and anti-inflammatory preparations that are aimed at pain and inflammation reduction. They are found in almost every ecosystem on Earth and are the most abundant type of biological entity. Influenzavirus B infects humans and seals, Influenzavirus C infects humans and pigs, Isavirus infects salmon and thogotovirus infects vertebrates and invertebrates, like mosquitoes and sea lice. Thus, each subsequent exposure acts as a sort of "booster," delaying HZ outbreak for decades.1 As people age, the ability of their immune system to suppress latent VZV virus gradually diminishes and, as a result, the risk of reactivation of latent VZV increases. Patients who are immunocompromised, whether due to HIV or immunosuppressive drugs, are at much greater risk for developing HZ and having a prolonged course of disease.6 As HZ is more typical in the elderly population, younger patients who present with symptoms should be tested for an underlying immune disease. When HZO occurs without vesicles, the telltale symptoms are pain, an odd sensation of hypoesthesia along the ophthalmic branch of the  fifth cranial nerve (5-1) and a decrease in corneal sensation. Various topical treatments for PHN are also available, including neurontin, nortriptyline and topical lidocaine cream. Elderly patients who are in good health and not taking immunosuppressive medications would likely benefit from the VZV vaccine, and ophthalmologists have a unique opportunity to provide this option to them.
I rarely have an oral herpes outbreak now even when we kiss, so I'm not sure what happened to mine either. At first, patients may have hypersensitivity due to in--flamed nerves but then they regress to hyposensitivity. HZO patients are at risk for anterior chamber complications as well, including keratouveitis and keratic precipitates in addition to photophobia and dramatic ocular pain. Furthermore, although neurologists can prescribe anti-depressants as a palliative treatment for PHN, they are not as effective as early, aggressive treatment—which could actually negate the need for anti-depressants.



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