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Once a person has the infection, the virus (a member of the herpesvirus family) stays in the body but usually lies dormant (or inactive). Babies who are infected in the womb usually show no symptoms of a CMV infection after they're born. Premature and ill full-term infants who are infected soon after birth are at risk for neurological and developmental problems over time. Although CMV infections that happen in kids after the newborn period usually don't cause significant illness, some kids may develop pneumonia, hepatitis (inflammation of the liver), or a rash. Older kids and teens who become infected may have mono-like symptoms, including fatigue, muscle aches, headache, fever, and enlarged liver and spleen. CMV can cause serious infections in people who have received organ transplants or those whose immune systems are weakened. If symptoms of CMV do appear, how long they last depends on how the infection happens and the age and general health of the person who has it. Among kids, the virus is commonly spread in childcare centers or preschool settings, where it passes easily through indirect contact, especially though contaminated toys. In the United States, about 1% of infants are infected with CMV before birth — usually only if the mother has developed a first-time CMV infection during pregnancy. Anyone with a new or past CMV infection can transmit the virus to others, even if he or she isn't showing any symptoms.
Doctors can diagnose the infection by taking a culture from a person's throat, urine, blood, or other body tissues or fluid.
In newborns, organ-transplant patients, those being treated for cancer, and kids who have immune disorders such as AIDS, CMV infection can be life-threatening. A mother who has a CMV infection shouldn't stop breastfeeding her baby — the benefits of breastfeeding are believed to outweigh the risks of passing CMV to the baby, who is unlikely to develop any symptoms if infected. For organ-transplant patients who are at risk of getting CMV from a transplanted organ, preventive therapies are available. Cytomegalovirus (CMV) is a member of a group of herpes-type viruses that can cause disease in different parts of the body in people. Special forms of gastritis: Classified under the special forms of gastritis are eosinophilic gastritis, lymphocytic gastritis, collagenous gastritis (Figure 8 ) as an additional manifestation in patients with collagenous colitis, and rare forms induced by infections with mycobacteria, Treponema pallidum, cytomegalovirus (Figure 9), measles viruses, parasites such as Stongyloides stercoralis or Anisakis marina, or fungi (Figure 10). The latter forms of gastritis, which are characterized by infection with opportunistic organisms or parasites, are rare findings.
This entry was posted in Gastritis and tagged Autoimmune gastritis, Crohn’s disease, Gastritis, Helicobacter pylori. But CMV infection can be serious for babies and people with weakened immune systems due to illness or medicines, or for an unborn child if the mother has the virus.


In a few cases, there are symptoms at birth, which can include premature delivery, being small for gestational age, jaundice, enlarged liver and spleen, microcephaly (small head), and feeding difficulties. For example, serious CMV infections before birth may cause developmental problems that affect a child for a lifetime. But transmission usually requires fairly close contact; the virus can be spread through saliva, breast milk, vaginal fluids, semen, urine (pee), and stool (poop). Blood tests also can look for certain antibodies that are part of the immune system's response to a CMV infection. These people may be treated with intravenous (IV) antiviral medication, usually in a hospital.
For pregnant women, women who might become pregnant, childcare personnel, and anyone who has close contact with children, hand washing can help reduce the risk of infection.
This article discusses CMV in people with weakened immune systems. Causes Most humans are exposed to CMV in their lifetime, but typically only individuals with weakened immune systems become ill from CMV infection.
In immunosuppressed patients or HIV-infected subjects with dyspeptic symptoms, however, they may occur more frequently and should, therefore, not be left out of account.
These babies are also at high risk for developing hearing, vision, neurological, and developmental problems.
On the other hand, infection in teens may last only 2 to 3 weeks and cause no lasting problems.
It also can be present in blood products and donated organs, causing infection after a blood transfusion or organ transplantation. Oral antiviral medicine also might be used at home once the infection is under control and no longer poses a serious risk. It's also a good idea to not share eating utensils with young kids and to avoid close contact with anyone who has the infection. Because these antiviral medicines can have serious side effects, doctors use them with caution, especially in children. However, serious CMV infections can occur in people with weakened immune systems due to AIDS, organ transplants, bone marrow transplant, chemotherapy, or medicines that suppress the immune system. A CMV infection may affect different parts of the body. Between 50% and 80% of people in the United States have had a CMV infection by the time they are 40 years according to the Centers for Disease Control and Prevention (CDC). Opportunistic infections are caused by organisms that do not usually lead to disease, but that take advantage of a damaged immune system. Rarely does it cause recurrent disease, unless the person's immune system is suppressed due to medication or disease. Therefore, for most people, CMV infection is not a serious problem. Primary CMV infection in pregnant women can cause harm to the developing fetus.


See: Congenital cytomegalovirus Symptoms The symptoms of CMV infection are similar to those of mononucleosis. A tissue biopsy is often required to be certain of the diagnosis (except in the eye or nervous system). Treatment Several antiviral medications are available to treat CMV. However, the drugs do not eliminate the virus from the body. Outlook (Prognosis) CMV infection in an immunocompromised person can be life threatening.
These include pregnant women as it can harm unborn babies and those with a suppressed immune system due to disease or drug treatment, such as organ transplant recipients or people infected with HIV. The virus remains dormant in the body, reactivating only when the body’s immune system is weakened.
Some of the symptoms include: Infants who are infected before birth usually show no symptoms of a CMV infection after they are born.
They may develop severe symptoms including hearing loss, blindness, neurological, and developmental problems over time. Some infants may have other symptoms at birth including premature delivery, jaundice, enlarged liver and spleen, small head or microcephaly, being small for gestational age, seizures, rash, and feeding difficulties.
Older children and healthy adults may have a few days or couple of weeks of mild illness with muscle pain, fatigue, headache, fever, and enlarged liver and spleen. The virus is spread via fluids like saliva, breast milk, vaginal fluids, semen, urine, and stool.
These setting allow for spread through indirect contact, especially though contaminated toys. In those who are particularly vulnerable for complications like newborn infants, organ-transplant patients, and people being treated for cancer or who have immune disorders such as AIDS, some antiviral medications may be used intravenously. Oral antiviral medication also may be used at home once the infection is under control and the patient is stable. Some of the drugs used include CMV-immune globulin (CMV-IVIG) and the antiviral drug Ganciclovir.
For those who have close contact with children, especially pregnant women or women, simple measures like hand washing may help. Other measures include are not sharing eating utensils, avoidance of intimate contact with anyone who has a CMV infection etc.



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