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Herpes simplex infection of the mouth and face, known as orofacial herpes simplex, herpes labialis, cold sores, or fever blisters, is a common, recurrent skin condition associated with infection by the herpes simplex virus (HSV). HSV infections occur in people of all races, of all ages, and of both sexes.Increasing age is associated with increased likelihood of infection.
The most common locations for HSV-1 infections include: Lips Mouth (including gums, tongue, roof of mouth, and inside the cheeks) Nose Chin Cheeks Shortly after exposure to the virus, a newly infected person may develop fluid-filled blisters, occurring singly or in a cluster of several blisters. Acetaminophen or ibuprofen may help reduce fever, muscle aches, and pain caused by cold sores.
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Up to 80% of Americans are infected with HSV-1 by the time they are 30 years old.Only 20% of people who are infected with HSV actually develop visible blisters or sores. These blisters may be yellow to gray and are fragile, so that many people never notice blisters but instead see tiny open sores (ulcers). Seek medical advice as soon as possible, especially if you are at risk for more serious complications. On occasion, however, a swab from the infected skin may be sent to the laboratory for viral culture, which takes a few days to grow. Furthermore, these cold sores may periodically come back in the same sites.Infections with HSV are very contagious and are spread by direct contact with the skin lesions. That means that approximately 80% of people with HSV infections have not been diagnosed and are unaware of their condition. Blood tests may also be performed.Untreated HSV infections will go away on their own, but medications can reduce the symptoms and shorten the duration of outbreaks. There are 2 types of HSV: herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). HSV-1 infections usually occur around the mouth, lips, nose, or face, while HSV-2 infections usually involve the genitals or buttocks. Because it so contagious, HSV causes a primary infection in most people who are exposed to the virus. In severe cases of HSV infection, cold sores may involve the entire lining of the mouth and both lips.


However, only about 20% of people who are infected with HSV actually develop visible blisters or sores. These severe infections may be accompanied by fever, sore throat, foul breath, and difficulty eating.Repeat (recurrent) HSV infections are often milder than the primary infection, though they look alike.
However, some people never develop the symptoms of a primary HSV infection and may mistake a recurrent infection for a primary infection.
Nevertheless, the virus remains in the body, hibernating in nerve cells.Certain triggers can cause the hibernating (latent) virus to wake up, become active, and travel back to the skin.
These recurrent HSV infections may develop frequently (every few weeks), or they may never develop.
Recurrent infections tend to be milder than primary infections and generally occur in the same location as the primary infection.Most people get cold sores as children, through contact with a friend or family member who is already infected with HSV. It can be spread (transmitted) by kissing, sharing eating utensils or drinking vessels, or by using the same towel.



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