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Did you study cocaine withdrawal to decide what that would look like once Thackery's supply runs out?
We see him compete to advance various surgical procedures, but he does it mostly out of ego so he'll always be considered the best. Really, I have to say that the prosthetics guy on this thing did an absolutely unbelievable job throughout, and there’s so little CGI in this whole series. Do you think Bertie made the right choice in remaining so loyal to Thackery, especially at the end when he realizes what's been going on? It’s difficult because Thackery does eventually go off the rails, but there’s no question that, at the beginning when we meet him, Thackery is a genius.
We've seen shocking surgeries all season, but the most jarring moment probably comes when we see that Eleanor's teeth have been removed because that's how doctors thought they'd cure mental illness. It must be hard to shoot in contemporary downtown New York but make every scene look and feel like it's set in 1900. Steven has just the most incredible people around him that he’s been working with for a long time. I think the reason no other director could have taken this on and done it the way that he did it is that he has done everything.
Actor Ian Somerhalder with volunteers from International Bird Rescue, Scott Steeper and Nancy Kaump, celebrating the launch of the Dawn "We All Love Wildlife" video series at International Bird Rescue in San Pedro, Calif.
Thackery discovers an unfortunate way to kick his cocaine habit in the form of 1900-era heroin. When she delivers that and when she finally comes through with the cocaine, he’s like, "She’s the most beautiful, loving person." He’s a desperate addict by this point.
Stanley Burns, who runs this archive of literally hundreds of thousands of photographs from this period in the world. What was really incredible is when you film on one of those outside days, you’d come to the exterior of the hospital and you’d walk on and everything would already be up and running. What does Steven Soderbergh, the consummate multitasker, bring to "The Knick" that no other director could? What’s great is the idea of being able to go into the next season and it could just pick up and hit the ground running, taking it further and exploring new territories.
He is brilliant, but by this point he’s in a desperate place and he’s not thinking straight. That was the one scene where I remember I turned to Steven at one point and said, “How on earth are we ever going to bring back Thackery from this?” Will we ever be able to redeem him from this? That’s the journey of what happens, but there’s no question that Bertie would have learned an awful lot, but he’s also had to withstand an awful lot. You’d do a shot in the carriage and it would pull up and you’d get out and 20 minutes later we’d be on to something else.

I’ve got a number of the scripts already and it’s just really exciting where we can take it. The idea of starving Thackery of his drug and then coming back and this more than ever was a brilliant way of climaxing.
He has an unbelievable wealth of material; he has medical documents that were handed between doctors at the turn of the century, he has instruments that were used at the time. I mean, in such a coked-up state, to be attempting something like that with this poor little girl, it’s a wild as it could get. It was so incredibly efficient, and they were so focused in getting those big outside scenes nailed so quickly. To have that is really extraordinary because I don’t know of any of the other directors you mentioned or any director that I’ve worked with who could do that and could hold the whole canal like he approached it at the speed with which he approached it.
Cornelia's wedding day arrives, but she's haunted by the thought of her clandestine abortion and her feelings for Dr. To go through that period of struggle, of not having the drug and then getting it and taking too much, was always, I felt, a great way to build him toward the end. He was there for every single operation and would be able to describe exactly how it would have been done, so we leaned on him tremendously. And the scary thing, when you do a show like this, is that what we’d be doing in 40 or 50 years’ time would make us think, "How on Earth could we have thought that was right?" How on Earth could a doctor really have believed that? There were very challenging days -- we were shooting real New York Chinatown for 1900 Chinatown. It was a wildly exciting time in terms of the breakthroughs they were making, probably this time in this period more than any other period.
We’d find a block in there that we’d dress and shoot, but you can imagine the logistics of trying to pull that off. And Edwards himself is given the chance to shine while Thack is out of commission, but he's left bloodied in the streets, knowing Cornelia is off vowing to love another man. For an actor to work with that is a real privilege because he’s so on top of all aspects of what’s going on that you’re kind of left just worrying about your acting, which is a great place to be because you’re so sure.
This was a stunner of a season finale, exemplifying the best of Steven Soderbergh's slow-burning drama. HuffPost Entertainment caught up with star Clive Owen, who plays Thackery, to discuss the finale. There’s something kind of great about that, about shooting a scene and there not being that dialogue of, “What if we did this?” or “What if we did that?” No.

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