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999 Cold Granular showed a significant antipyretic and analgesic effect, it could inhibit the carrageenan induced inflammation, antagonize the endotoxin induced fever, and promote the amount for expression of cytokines in rats' splenic tissue with pneumococci infection to some extent.
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The relaxation cough, sputum, throat pain, View expectorants, Topic Product Details from NISSIN PHARMACEUTICAL INDUSTRIES CO., LTD. The Chinese materia medica in 999 Cold Granularshowed certain protective effect on acetaminophen induced liver damage.

The study came to the conclusion that 999 Cold Granular has a potent antipyretic, analgesic and anti-inflammatory effects, Chinese materia medica & Western materia medica in GML showed markedly synergism and complementation, and Chinese materia medica in it has liver protective effect.

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