Herpes 2 vaccine release date uk,herpes skin eruptions,how do they test for herpes type 2,alternative remedies for depression and anxiety journal - Tips For You

admin 04.08.2014

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced the launch of phase 1 clinical trials into an investigational genital herpes vaccine, according to an agency press release Friday. Currently, there is no preventive vaccine for genital herpes, Approximately three-quarters of a million people are infected with herpes simplex virus type 2 (HSV-2) and herpes simplex virus type 1 (HSV-1) annually. The investigational vaccine candidate, called HSV529, will be tested in the trials for safety and the its ability to illicit an immune response. The clinical trial is expected to enroll 60 adults ages 18 to 40, who will be divided into three groups of 20 participants each.
Within each of the three groups, researchers will randomly assign participants to receive three doses (0.5 milliliters each) of the investigational HSV529 vaccine (15 participants) or a saline-based placebo vaccine (five participants). Early in 2012, Glaxo SmithKline pulled the plug on the trials on their vaccine, Simplirix, after it failed clinical trials.


HSV-2 is generally transmitted through sexual contact and can spread even when the infected individual shows no symptoms. Depakote Delayed-Release (Divalproex Sodium XR) may be prescribed alone or in combination with other drugs to treat acute manic episodes related to bipolar disorder, certain seizure disorders, or to prevent migraine headaches.
The three vaccinations will occur at study enrollment and again one month and six months later. Robert has been covering news in the areas of health, world news and politics for a variety of online news sources. The investigational vaccine is being tested among study participants who have previously been infected with HSV to determine if it may pose any safety issues.
Participant safety will be monitored throughout the course of the trial, and researchers will follow participants for six months after they have received their last dose of vaccine.


Once in the body, HSV migrates to nerve cells and remains there permanently, where it can reactivate to cause painful sores and blisters. Blood samples will be used to evaluate the candidate vaccine’s ability to stimulate immune system responses to HSV-2, including production of virus-specific antibodies and T-cell responses.



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