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Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. At least 85% of the world population have serological evidence of having had a herpes simplex infection.
Herpes simplex infections can be primary- the first infection in a previously seronegative patient – or recurrent. Follows direct contact with an infected individual, either with active disease or shedding viral particles during a latent phase. Trigger factors include minor trauma, febrile illnesses, ultraviolet light and possibly stress. Complications include: Erythema multiforme (65% of attacks are triggered by a herpes simplex recurrence within the preceding two weeks), eczema herpeticum, persistent ulceration in the immunocompromised and keratoconjuctivitis.
These are transmitted sexually, and begin to appear at puberty or are spread from a mother’s genital tract infection to a newborn child. The median recurrence rate is about one attack every 3 months for HSV-2 infections (and far less often for genital HSV-1 infections).
Prevention is difficult because the virus is ubiquitous and spread by people with no obvious active infection. Those looking after patients with atopic eczema should stay away if they have cold sores because eczema herpeticum is so serious.
Suppressive long-term antiviral therapy may be needed for particularly frequent or severe relapses. The decision to use oral antiviral therapy for recurrent facial herpes simplex depends on the frequency and severity of relapses and the damage being done to the quality of life.


Long-term suppressive therapy can be considered in genital herpes relapsing more than 5 times per year. IVD is NOT for Sale in the United States but may be available in certain countries outside of the United States, please contact your local distributor for more information. By age 30, 50% of adults of high economic status in the US are seropositive to HSV-1, in contrast to 80% of those of lower status. The introduction of aciclovir (DNA polymeras inhibitor) was a milestone although it does not eradicate the virus.
They are closely related but differ in their epidemiology, although both are spread by close personal contact.
Regular use of condoms helps prevent genital herpes and a high protection factor sunscreen helps to prevent recurrent facial lesions. Studies have shown that HSV Type 1 infects tissues such as lung and esophagus and HSV Type 2 infects the genitals and anus.
This antibody does not cross-react with cytomegalovirus, Epstein-Barr virus, or varicella zoster virus and is compatible with formalin fixation; however, prolonged fixation can be detrimental to HSV staining. Se o virus for resistente, existem outras alternativas de tratamento possiveis, incluindo os medicamentos Foscarnet, Vistide.
Depois de surgirem estes sintomas, o aparecimento de bolhas ou de manifestacoes cutaneas na zona da boca pode ocorrer em poucas horas, ou em 2 ou 3 dias.
Quando aparecem, as bolhas estarao rodeadas por uma zona avermelhada, com alguma dor associada.O primeiro episodio pode ser leve ou grave.
A cultura viral, o teste de ADN viral, ou o teste de Tzanck da lesao da pele podem revelar o virus do herpes simplex.Sintomas da herpes genitalNo inicio da herpes genital irao aparecer alguns sintomas previos ao surgimento das feridas, tais como comichao, dor, ardor, estados febris, dor muscular, calafrios e mal-estar.


Depois, aparecerao as feridas em forma de bolha, rodeadas com margens avermelhadas, com um liquido dentro. Quando a ferida fica proxima do anus, essas feridas provocarao ardor durante a miccao ou ao defecar. Outros sintomas habituais na herpes genital e a falta de apetite e o aparecimento de inguas (ganglios linfaticos aumentados) nas virilhas. A herpes genital pode ocorrer em toda a area genital, podendo aparecer na vulva, no penis, na zona perianal e no anus.
Nalguns casos, pode mesmo ocorrer internamente, no canal vaginal, no colo do utero ou na uretra. Assim, e normal, mesmo depois da primeira crise debelada, que volte recorrentemente a sofrer de herpes. Quando aparecem as feridas da herpes, o seu tratamento e feito com farmacos antivirais, e tambem, com anti-inflamatorios, durante um periodo habitual de 10 dias. Os medicamentos antivirais tomados por via oral podem ajudar os sintomas a desaparecerem mais cedo e diminuir a dor.Aciclovir, famciclovir e valaciclovir sao os tres tratamentos orais atualmente disponiveis no mercado farmaceutico. No entanto, o uso de medicamentos apenas serve para acelerar o desaparecimento e para aliviar os sintomas, ja que no caso da herpes, a infecao e limitada, desaparecendo naturalmente ao fim de algum tempo, mesmo sem se fazer nada.
Maio 2013 by adminComentarios no Forum (4)nete santos says Agosto 25, 2014 at 7:05 pmboa tarde !!



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