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Varicella-zoster virusThe varicella-zoster virus (VZV), also known as human herpesvirus 3 (HHV-3), is one of the eight herpesvirus known to affect humans (and other vertebrates). Varicella-zoster virus causes chickenpox as a primary infection and rarely VZV encephalitis. The Varicella-zoster virus can remain dormant in the host and later reactivates to induce shingles disease (herpes zoster, zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete) and post-herpetic neuralgia.


Within the body it is combatted by a number of drugs including vidarabine, zoster immune globulin (ZIG), and acyclovir.
It's lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. It was developed by Merck, Sharp and Dohme in the 1970s from a virus isolated by Mishiaki Takahashi and identified as Oka.


It had a series of tests in the 1980s and was offered to the FDA for approval in 1990 and was finally passed in 1995.




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