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From Chiron Biocine, Emeryville, California, and the University of Washington School of Medicine, Seattle, Washington. Requests for Reprints: Andria Langenberg, MD, Chiron Biocine, Chiron Corporation, 4560 Horton Street, Emeryville, CA 94608. Anyone can submit a comment any time after publication, but only those submitted within 4 weeks of an article’s publication will be considered for print publication. From Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and Abbott Laboratories, Abbott Park, Illinois. Grant Support: By the National Heart, Lung, and Blood Institute (HL58755) and by an Established Investigator Award from the American Heart Association (Dr. Data from several studies have suggested that persons with coronary heart disease have an increased prevalence of chronic infection with such agents as Chlamydia pneumoniae, Helicobacter pylori, herpes simplex virus, and cytomegalovirus (1). Primary herpetic gingivostomatitis is a relatively common viral infection of the oral mucosa. Government and Non-Government Dental Colleges in Bangladesh In Bangladesh there are 1 government Dental College and 6 Government Dental units, 11 non-government Dental Colleges (BMDC approved) . One hundred thirty-three patients were seropositive for only HSV-2 by Western blot, and 249 patients were HSV-1-seropositive only.


One month after publication, editors review all posted comments and select some for publication in the Letters section of the print version of Annals. Baseline IgG Antibody Titers to Chlamydia pneumoniae, Helicobacter pylori, Herpes Simplex Virus, and Cytomegalovirus and the Risk for Cardiovascular Disease in Women.
Ridker, MD, Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.
Ridker: Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.
Hennekens, Buring, and Kundsin: Department of Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, MA 02215.
In addition, it has been hypothesized that infection may be a risk factor for acute coronary events (2). Among these college Dhaka Dental College (DDC) is the most prestigious dental college of Bangladesh. Among HSV-1-seropositive patients, one immunization produced increases in gD2 and gB2 ELISA antibody titers and HSV-2-neutralizing antibody titers that were 3 to 5 times greater than those in persons with naturally acquired HSV-2 infection. The dose of each glycoprotein at each injection and the number of patients receiving each dose are shown.


Herpes simplex virus type 2 neutralizing antibodies in patients 2 weeks after the third immunization with the 30- micrograms vaccine. However, chronic infection is also more prevalent among smokers, elderly persons, and persons of lower socioeconomic status, and persons with a history of coronary disease may be more susceptible to subsequent infection. Address: Mirpur-14, Dhaka-1206 Tel- 8017146 In Brief Dhaka Dental College (DDC) is the most prestigious dental college of Bangladesh.
Among HSV-seronegative patients, frequency analysis assays showed a marked increase in the precursor frequency of gD2- and gB2-specific T cells after vaccination: T-cell responses after two immunizations were equal to the responses of HSV-2-seropositive patients and were sustained at day 180. The geometric mean titer (GMT) to glycoproteins B2 and D2 for persons with naturally acquired HSV-2 infection are 3560 and 1209, respectively (see text). Therefore, it is uncertain whether the associations between infection and coronary heart disease that have been observed in retrospective and cross-sectional studies were caused by confounding or represent a result of ischemic heart disease rather than a cause (3).



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