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Though more common near the lips, grouped blisters (vesicles) can occur anywhere in herpes infections. The first eruption of skin or mouth sores with the herpes simplex virus (HSV) is called primary herpes. This Site and third parties who place advertisements on this Site may collect and use information about your visits to this Site and other websites in order to provide advertisements about goods and services of interest to you. If you would like to obtain more information about these advertising practices and to make choices about online behavioral advertising, please click here.

This may be more severe than the more commonly recognized than secondary, or recurrent, herpes infections, which are also called cold sores or fever blisters.Either herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2) can cause infection.
Most people never even know they have been infected, as their immune system suppresses symptoms.
Most commonly, primary herpes is seen in children with painful blisters and erosions of the gums and the skin around or lining the mouth. There may also be fever, swollen lymph nodes in the neck, irritability, and a poor appetite.

If HSV was introduced on other body sites, there will be painful blisters and sores in that location (finger, face, genitals) with swelling and similar systemic symptoms. Both conditions are highly contagious and are spread by direct contact with the lesions of another infected individual such as a playmate, parent, or caretaker.

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