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The varicella zoster virus is a type of herpes simplex virus (HSV) but is not the same as the herpes simplex virus that causes genital herpes. Herpes zoster is not a virus but a syndrome that arises with reactivation of the varicella zoster virus (VZV) years or even decades after chickenpox.
Herpes zoster is the same as shingles, an alternative and commonly used name for this condition.
Herpes zoster is more likely to occur in a person with a depressed immune system and the elderly.
Herpes zoster, commonly known as just zoster or shingles, is a condition caused by the reactivation of the varicella zoster virus (VZV). Shingles is the syndrome where a painful skin rash marked by the presence of tiny blisters usually forms on a dermarcated area on the skin surface of the head or trunk.
Once the virus reactivates, it causes inflammation of the nerves and is therefore also known as acute posterior ganglionitis. However, shingles often arises for no known reason even in a person without any of these contributing factors. Images from CDC (1)The main symptoms of herpes zoster (shingles) is an itchy skin rash and pain which has been discussed in detail below.
Herpes zoster mainly affects sensory nerves but motor nerves that control muscles may also be affected.
Pain that lasts for longer than a month, even after the rash clears, is most likely a complication of shingles known as post-herpetic neuralgia.
All images have been sourced from the Dermatology Atlas (2) courtesy of Samuel Freire da Silva, M.D.
Tricyclic antidepressants, anticonvulsants and corticosteroids along with anesthetics may be needed for post-herpetic neuralgia. Treatment should be commenced immediately once a diagnosis of shingles is made, preferably within the first few days of the onset of the rash. Zoster vaccine to prevent shingles and should be considered only for a person older than 60 years of age.
Ask a Doctor Online Now!Please note that any information or feedback on this website is not intended to replace a consultation with a health care professional and will not constitute a medical diagnosis. The signs and symptoms of genital herpes, also commonly referred to as HSV-2 (Herpes Simplex Virus – Type 2) may differ from one person to another. Listed below, are some of the signs and symptoms that are commonly associated with the first outbreak of genital herpes. In addition to the above, persons suffering from herpes simplex virus may feel a sense of being sick.
Even though the signs and symptoms commonly linked with the initial outbreak usually clear, it is important to state that the virus stays in a dormant state for years in the closest nerve.
Whereas recurrent is normally mild compared to the initial outbreak, there are signs and symptoms that are enough to indicate to someone that they are experiencing an outbreak. As pointed out earlier, the signs and symptoms in recurrent herpes simplex virus are not only mild, but shorter. As the years go by, recurrent herpes simplex virus becomes less common in addition to becoming less severe. There are other herpes symptoms other than the ones mentioned above that are normally displayed by persons suffering from herpes simplex virus. According to the CDC, it is believed that up to 60% of people who suffer from genital herpes do not display signs and symptoms. My son came down with herpes simplex 1-(mild to light blistering around the lip area, inside lip) I took him in and they gave him Aclovair in pill form, they went away for about 8 months, he says there back.
Conditions that cause vomiting or acid reflux, such as the eating disorder bulimia, can damage tooth enamel. Gingivitis, also generally called gum disease or periodontal disease, describes the events that begin with bacterial growth in your mouth and may end -- if not properly treated -- with tooth loss due to destruction of the tissue that surrounds your teeth.
Tooth decay occurs when foods containing carbohydrates (sugars and starches) are left on the teeth. Dental bonding is a procedure in which a tooth-colored resin is applied and hardened with a special light, ultimately "bonding" the material to the tooth to improve a person's smile. Veneers (sometimes called porcelain laminates) are wafer-thin, custom-made shells that cover the front surface of teeth, changing their color, shape, size or length.
Recontouring or reshaping is a procedure in which small amounts of tooth enamel are removed or shaped to change a tooth's length, shape, or surface.
Braces can correct crooked teeth or a misaligned bite, and can improve the health and appearance of anyone's smile, adult or child.
Many teeth-whitening systems are available, including whitening toothpastes, over-the-counter gels, rinses, strips, and trays, and whitening agents obtained from a dentist. Amalgam tattoos occur when a tiny piece of amalgam filling embeds in your cheek or gum during or after dental work.
Also called aphthous ulcers, canker sores can show up on your tongue, cheek, and even your gums. Strep infection often produces a distinct pattern of white patches in the throat and on the tonsils, as well as red swollen tonsils. Small amounts of the candida fungus are present in the mouth, digestive tract, and skin of most healthy people and are normally kept in check by other bacteria and microorganisms in the body.
Tonsil stones (also called tonsilloliths) form when bacteria and mucus get trapped and calcify in your tonsils’ nooks and crannies, leaving a hard piece of matter and a bad taste in your throat. Cold sores (fever blisters) are caused by the herpes simplex virus (HSV), passed on through contact with infected skin or body fluid.


You can't cure HSV or a cold sore, but you can alleviate the pain it causes by avoiding spicy or acidic foods, applying ice, and using over-the-counter remedies. The virus gains entry into the body, not through intact skin, but through mucous membranes, such as the oral region, vagina, tip of the penis, or the eye. However, before this happens, the virus gains entry to the nerve cell end-plates (structures that help us to feel things like pain and temperature), present at the skin surface. HSV has specifically chosen the nerve cell body and ultimately the ganglion (HSV-1 resides in the trigeminal ganglion; HSV-2 resides in the sacral ganglia) as a site where it remains dormant. Within a day of infection, the naked virus (nucleocapsid) arrives at the nerve cell nucleus, and it “injects” its genetic material (DNA).It then resides in the nerve cell nucleus in a dormant (latent) form. According to most researchers, virus replication will not occur at this stage and no new virus particles will be formedThe precise molecular mechanisms for this event (establishment and maintenance of latency) are unknown, but appear to reflect an interplay between viral and nerve cell factors. However, other researchers argue that a low level of replication must occur in order to keep the virus machine “well oiled”. It is important, from the virus “survival” point of view, to be able to “fire up” and begin to replicate should circumstances become uncomfortable inside the neuron (i.e. We do not understand why stress and sunshine, for example, tend to trigger HSV reactivation. After the active phase of the infection resolves, the virus stays dormant at the spinal nerve root, specifically the dorsal root ganglion. It mainly affects the sensory nerves but can sometimes involve the motor nerves – those nerves that control muscles in the body.
These symptoms usually settle after 10 to 15 days but can take up to one month to resolve completely.
This gives rise to symptoms such as paralysis of the diaphragm, bladder and bowel problems, cranial nerve palsies and muscle weakness.
A dermatome is an area of the skin which is innervated by nerves from a single spinal root.
However, if the infection occurs in a vaccinated person it is usually less severe and shorter in duration. The exaggerated signal does not extend beyond the insular cortex (thin arrow), but does involve the cingulate gyrus (thick arrow).
According to the CDC (Center for Disease Control), most people (men and women) do not even know that they have the disease, hence the high number of infections. Persons suffering from the disease may experience temperatures of up to 100 degrees Fahrenheit. Then again, it is important to point out that the sores normally heal without leaving a scar. The key reason for this is because the body has already generated sufficient protective antibodies (i.e.
These include swollen lymph nodes, lower back pains, headaches, high fevers, painful swollen blisters which tend to develop around the affected area, discharge from the penis and vagina, aching of the muscles as well as burning sensations in the genital area. He is 17 very vain about his appearance, works at safeway with the public, is there anything over the counter he could get for this that wll help? This semi-translucent, hard, outer layer of the teeth has an important job: protecting teeth from the daily wear and tear of biting and chewing, as well as temperature extremes from hot or cold foods and drinks. Over time, the constant clenching and friction can damage teeth and other health complications can arise.  Bruxism is often worst when you sleep -- that's when you can't control it. Among the easiest and least expensive of cosmetic dental procedures, bonding can repair chipped or cracked teeth, close gaps, change the shape of teeth, or be used as a cosmetic alternative to silver amalgam fillings. The procedure is usually done to improve appearance by creating more harmony or balance in the look of the smile. The crown, when cemented into place, fully encases the entire visible portion of a tooth that lies at and above the gum line. Otherwise your tooth could be damaged further or become infected, possibly causing you to end up losing the tooth. Many people use this opportunity to replace silver amalgam fillings with tooth-colored composites. Implants provide a strong foundation for fixed (permanent) or removable replacement teeth that are made to match your natural teeth. Braces work by applying continuous pressure over a period of time to slowly move teeth in a specific direction. Brackets -- the parts that attach to each tooth -- can be clear, tooth-colored, or multi-colored. Porcelain veneers and crowns can correct crooked teeth, an uneven gum line, and other chipped, worn, and discolored dentistry. Teeth whitening is ideal for people who have healthy, unrestored teeth (no fillings) and gums.
The silver in the amalgam leaches into your mouth's soft tissue, resulting in a blue-gray "stain" that looks a bit like a tiny tattoo. However, certain illnesses, stress, or medications can disturb the delicate balance, causing the fungus candida to grow out of control, causing thrush. They are not as common, but cold sores can appear anywhere on the face, including on the cheek, chin, or nose. The virus will first replicate (make copies of itself) inside surface cells at these sites, eventually killing the infected surface cells. The end-plates connect to the more deeply located nerve cell body through an elongated nerve fibre or axon. It is from these locations that the virus may reactivate from its dormant state to the respective innervated (nerve-cell-serviced) body areas.


When this happens, new virus particles are created and transported back to the skin and mucous membranes through the neuronal highway.
We also think that HSV particles not only travel down to the skin and mucous membranes, but may also travel in the opposite direction leading them closer to the brain.
Shingles can affect any age group but is more commonly seen in the elderly and those with depressed immune defenses. Although the peripheral nerves to the trunk is commonly affected, the virus may cause inflammation of any part of the nervous system, even the brain (encephalitis), meninges (meningitis) or both (meningoencephalitis). According to most physicians, the signs and symptoms are quite severe during the initial outbreak. Other areas where the sores and blisters may appear other than the genital area include the buttocks plus thighs.
Purging can also trigger swelling in the mouth, throat, and salivary glands as well as bad breath.
The same goes for any condition that causes frequent vomiting, from gastrointestinal problems to eating disorders. The bacteria, acid, food debris, and saliva combine to form plaque, which clings to the teeth.
Veneers offer a conservative approach to changing a tooth's color or shape compared to crowns, but the process is not reversible. Instead of individual crowns, some patients may have attachments on their implant that support a removable denture.
Complete dentures are used when all the teeth are missing, while partial dentures are used when some natural teeth remain. Cosmetic dentists can make a dramatic difference in a person's smile and overall oral health, but the work must be carefully planned. Amalgam tattoos pose no harm, but it's not likely an amalgam tattoo if the blue-gray spot grows or changes color. Triggers include hypersensitivity, infection, hormones, stress, and not getting enough of some vitamins.
A weakened immune system, antibiotics, diabetes, or certain medications such as inhaled corticosteroids can give candida a chance to grow wild. In a person with normal immunity, the immune system is quickly mobilized to contain the primary infection. This cell in turn is connected to “serially coupled” layers of internal nerve cells, which eventually lead to a ganglion, which is a collection of nerve cell bodies just like a node in an electricity grid. They then begin to replicate in the surface cells, creating a blister in the form of a cold sore or genital herpes.
Some researchers suggest that healthy immunocompetent people may, in fact, harbor dormant virus inside the brain. The varicella zoster virus causes the common childhood infection known as chickenpox which resolves after a few weeks.
The virus targets certain nerves with symptoms such as the rash and pain being isolated to those areas of the skin supplied by a single spinal nerve.
Anorexia, bulimia, and other eating disorders can also cause serious nutritional shortfalls that can affect the health of your teeth. The American Dental Association asserts that the mercury in amalgam combines with other metals to render it safe for use in filling teeth. There are even "invisible" braces that use a series of clear, plastic molds to gradually move the teeth into alignment. Persistent, severe canker sores can be treated with numbing creams or prescription treatments. HSV-1 damages the skin as it reproduces itself, creating cold sores that last about a week.
The virus also has an “over coat”, the envelope, which is necessary for the “docking” procedure when the virus infects a cell. Through such intricate connections the nerve cells eventually lead into and communicate with the central nervous system or the brain.
However, the virus remains dormant for long periods of time in the body and may sometimes reactivate to cause inflammation of the nerve roots. Although shingles resolves within a month, it can sometimes lead to complications or the pain can persist for months thereafter (post-herpetic neuralgia). In other words, an HSV particle without the envelope is not infectious, since it cannot enter the cell. The axons are protected by “myelin blankets”, just like the insulating material around electrical wires, but the endings are bare, as are the nodes where one nerve cell extension connects with the next (synapse).
This does not happen in every person who had chickenpox and is more frequently seen in diminished immune states. Vaccines provide an effective albeit not guaranteed protection against developing shingles. In contrast to A and B, panel C demonstrates relative effacement of sulci posteriorly in both hemispheres (thin arrow), compared with normal sulcal spaces anteriorly (thick arrow).



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