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Herpesvirus: One of a family of double-stranded DNA viruses that cause common infections in humans.
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All members of this family are double-stranded DNA viruses with large complex genomes that replicate in the nucleus of the cell. Because replication occurs inside the host nucleus, herpesviruses can use the host's transcription machinery and DNA repair enzymes to support a large genome with complex arrays of both essential or so-called dispensable genes.


The dispensable genes enhance the cellular environment for virus production, defend the virus from the host immune system and promote cell to cell spread.
The large numbers of dispensable genes are in reality required for a productive in vivo infection.




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