Recurrent herpes type 1 genital,drying out genital herpes sores,cold sores joint pain - Good Point

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Use of images for any purpose including but not limited to research, commercial, personal, or non-commercial use is prohibited without prior written consent. Twenty-seven per cent of 70 patients with a history of recurrent herpes genitalis but no concomitant history of recurrent oral or peri-genital disease, had no detectable neutralising antibody against type 1 or type 2 herpes simplex virus; the prevalence and levels of neutralising antibody were similar to 53 patients with no history of herpetic disease and significantly lower than 67 patients with a history of recurrent herpes genitalis in association with oral or peri-genital disease all of whom had neutralising antibody against both virus types.
The results indicate that the failure to detect immunising and immunoprecipitating antibody in an induvidual's serum is compatible with a long and even severe history of recurrent herpes genitalis and consequently that the development of neutralising antibody does not necessarily indicate an episode of primary herpetic disease.
ReferencesAdam E, Kaufman RH, Melnick JL, Levy AH, Rawls WE (1973) Seroepidemiologic studies of herpes virus type 2 and carcinoma of the cervix III. JavaScript is currently disabled, this site works much better if you enable JavaScript in your browser. There were similar differences between groups for immunoprecipitating antibody where 80% of patients with herpes genitalis alone had no detectable immunoprecipitating antibody. Am J of Epidemiol 98:77–87Adam E, Dreesman GM, Birch J, Melnick JL, Kaufman RH, Powell KL, Purifoy DJM (1981) Herpes simplex virus type 2 non-structural delayed early (?) proteins in squamous cell genital neoplasms and antibody prevalence to these antigens.

Intern Workshop on Herpesviruses, Bologna, Italy, Esculapio Co., ItalyCatalano WL, Johnson LD (1971) Herpesvirus antibody and carcinoma in-situ of the cervix. Proceedings of the Intern Conf Human Herpesviruses, Atlanta, Georgia, Elsevier, New YorkBabalola GO (1981) An investigation of anti-herpes simplex virus (HSV) type 1 antibodies in human sera by immunodiffusion, neutralisation and immunoprecipitation. MSc Qualifying Thesis, University of BirminghamKillington RA, Yeo J, Honess RW, Watson DH, Duncan BE, Halliburton IW, Mumford J (1977) Comparative analyses of the proteins and antigens of five herpesviruses. Immunity 45:761–767Patterson WR, (1979) Antibody to herpes simplex virus type 2 specified antigens (s) in sera of women with and without squamous cell carcinoma of the uterine cervix. Diss Abstr Int B 39:4197Pauls FP, Dowdle WR (1967) A serological study of herpesvirus hominis strains by microneutralisation tests.
Amer J Obst Gynaec 107:710–716Rawls WE, Iwa moto K, Adam E, Melnick JL, (1970) Measurement of antibodies to herpes virus type 1 and 2 in human sera. Z Immunforsch exp Ther 124:24–29Skinner GRB, Thouless ME, Jordan JA (1971) Antibodies to type 1 and type 2 herpes virus in women with abnormal cervical cytology.

Saunders Limited, LondonSkinner GRB, Whitney JE, Hartley CE (1976) Detection of type-specific antibody to herpes simplex virus type 1 and type 2 in human sera by complement-fixation tests. Karger, Basel, SwitzerlandSkinner, GRB, Woodman CBJ, Hartley CE, Buchan A, Fuller A, Durham J, Synnott M, Clay JC, Melling J, Wiblin C, Wilkins J (1982b) The preparation and immunogenicity of vaccine Ac NFU1(S?) MRC towards prevention of herpes genitalis in human subjects.
Br J Ven Dis in pressSprecher-Goldberger S, Thiry L, Gould J, Fassin Y, Gampel C (1972) Increasing antibody titres to herpes simplex virus type 2 during follow-up of women with cervical dysplasia. Am J Epidemiol 97:103-XXXTaylor-Robinson D, Thomas BJ (1980) The role ofChlamydia trachomatis in genital tract and associated diseases.

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