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The AOCD was recognized in 1958 as a Specialty College of the American Osteopathic Association.
Syphilis is a sexually transmitted disease (STD) that can have very serious complications when left untreated, but it is simple to cure with the right treatment.
Basic fact sheets are presented in plain language for individuals with general questions about sexually transmitted diseases. You can get syphilis by direct contact with a syphilis sore during vaginal, anal, or oral sex. Syphilis has been called a€?the great imitatora€™ because it has so many possible symptoms, many of which look like symptoms from other diseases. Any sexually active person can get syphilis through unprotected vaginal, anal, or oral sex. During the first (primary) stage of syphilis, you may notice a single sore, but there may be multiple sores. A syphilis infection is called an a€?earlya€™ case if a patient has been infected for a year or less, such as during the primary or secondary stages of syphilis. Because syphilis sores can be hidden in the vagina, anus, under the foreskin of the penis, or in the mouth, it may not be obvious that a sex partner has syphilis.
Syphilis is known as the "great imitatora€? because of its varying clinical signs and symptoms.
The AOCD now oversees 27 dermatology residency programs that are currently training 119 residents in dermatology. Sores can be found on the penis, vagina, anus, in the rectum, or on the lips and in the mouth. The painless syphilis sore that you would get after you are first infected can be confused for an ingrown hair, zipper cut, or other seemingly harmless bump. Have an honest and open talk with your health care provider and ask whether you should be tested for syphilis or other STDs.
However, if not treated immediately, the baby may develop serious problems within a few weeks.
If you do not receive treatment, you can continue to have syphilis in your body for years without any signs or symptoms.

People who have a€?earlya€™ syphilis infections can more easily spread the infection to their sex partners. Unless you know that your sex partner(s) has been tested and treated, you may be at risk of getting syphilis again from an untreated sex partner.
The infection is characterized by episodes of active disease (primary, secondary and tertiary) with latent periods in between. The non-itchy body rash that develops during the second stage of syphilis can show up on the palms of your hands and soles of your feet, all over your body, or in just a few places. It can also make it more likely you will deliver your baby too early or stillborn (a baby born dead). Untreated babies can have health problems such as cataracts, deafness, or seizures, and can die.
The rash can show up when your primary sore is healing or several weeks after the sore has healed. The majority of early syphilis cases are currently found among men who have sex with men, but women and unborn children are also at risk of infection.
To protect your baby, you should be tested for syphilis during your pregnancy and at delivery and receive immediate treatment if you test positive. However, when it does happen it is very serious and would occur 10a€“30 years after your infection began.
Follow-up testing by your health care provider is recommended to make sure that your treatment was successful. Symptoms of the late stage of syphilis include difficulty coordinating your muscle movements, paralysis (not able to move certain parts of your body), numbness, blindness, and dementia (mental disorder). Even though the sore goes away, you must still receive treatment so your infection does not move to the secondary stage. Other symptoms you may have can include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue (feeling very tired). In the late stages of syphilis, the disease damages your internal organs and can result in death.
Without the right treatment, your infection will move to the latent and possibly late stages of syphilis.

The lesion can be accompanied by swollen lymph glands in the region as well as fever, and discomfort.Secondary syphilis presents as a rash characteristically on the palms of the hands and soles of the feet. They are only distinguished from the tertiary form by the time of onset and by the presence of spirochetes in the serum. Patchy hair loss on the scalp may occur.Tertiary syphilis develops 5-20 years after the first exposure. Tertiary syphilis may also affect other body systems like the brain, blood vessels and eyes.
Dementia-like symptoms can also occur.Latent phases occur between the three stages of syphilis. The only way to verify a syphilis infection during a latent period is to test the patienta€™s blood.Diagnosis of syphilis is made from a blood test that uses antigens.
A doctor may choose to perform a biopsy of an ulcer to distinguish syphilis from other diseases. Examination of a lesion under a microscope using immunofluorescence can help distinguish a primary and secondary ulcer.
If the individual has other body systems involved, other tests like an electrocardiogram, lumbar puncture, or an angiogram may be required.Penicillin G is the treatment of choice for a patient with syphilis. If a penicillin allergy exists, tetracycline, erythromycin or ceftriaxone can be used as alternative treatments. It is not intended nor implied to be a substitute for professional medical advice and shall not create a physician - patient relationship.
If you have a specific question or concern about a skin lesion or disease, please consult a dermatologist. Any use, re-creation, dissemination, forwarding or copying of this information is strictly prohibited unless expressed written permission is given by the American Osteopathic College of Dermatology.

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