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Because enzymes are proteins, they can work only under certain conditions of temperature and pH. Enzymes play a very important role in the chemical reactions involved in both cellular and extracellular processes.
Lock and Key Theory: This is one of the theories that explain the working mechanism of enzymes. The right substrate will fit into the active site of the enzyme and form an enzyme-substrate complex.
To be more precise, once the enzyme identifies the right substrate, the shape of its active site changes so as to fit the latter exactly. Factors that Affect Enzymes' Action: The activities of enzymes are affected by various factors, like the temperature, pH, and concentration.
Metabolic enzymes are function inside your cells, where they help the cell carry out a variety of functions related to its reproduction and replenishment of the cells.
Did you know that 90 percent of your digestion and absorption takes place in your small intestine?
From here, the micro-nutrients are absorbed into your bloodstream through millions of tiny villi in the wall of your gut.
Fortunately, you get (or should be getting) many enzymes from the foods you consume—particularly, raw foods.  These foods help the digestion of your food and really help improve the overall function of your digestive tract. A lot of people in our society today have some issues with insufficient enzyme production and that it is at the the root of our digestive system issues today. An enzyme acts by binding to a substrate, the substance that will be acted on by the enzyme. In competitive inhibition, the inhibitor molecule binds to the active site, not allowing the substrate to bind.
Like any other protein, enzymes are also made up of long chains of amino acids held together by peptide bonds.
While the first two types are produced by the body itself, the third type is derived from the food we eat. The production of enzymes is carried out by the cell, based on the instructions from the genes of that cell.
Each enzyme acts upon a specific target called substrate, which is transformed into usable products through the action of the enzyme.
As per this theory, each enzyme has a specific area (called active site) that is meant for a particular substrate to get attached. Human body produces numerous enzymes that are responsible for a wide range of chemical reactions, which are necessary for our survival.
Your Digestive health is used to maximize the digestion process and improve how your body assimilates and breaksdown food. Raw foods are enzyme-rich, and consuming them decreases your body’s burden to produce its own enzymes.

Former skinny malnourished high-schooler to overweight college party animal to professional athlete, who is currently living his life at Peak Performance.
While some living organisms (like bacteria) are unicellular, humans have thousands of cells in their body. Enzymes play an important role in performing or controlling a host of chemical reactions that take place in the body. Metabolic ones are mainly responsible for reactions related to detoxification and energy production. The active site of the enzyme is complementary to a specific part of the substrate, as far as the shapes are concerned.
Once the reaction is complete, and the products are released, the active site remains the same and is ready to react with new substrates. As this theory explains the working mechanism of numerous enzymes, it is widely accepted than the lock and key hypothesis.
I can’t tell you enough how important your digestive health is for your overall health. Some enzymes, like the ones in your gut, break down food and compress it into smaller compartments. Joseph has studied and learned from some world renowned healers, psychologists, nutritionists, naturopathy's, and doctors that have helped thousands of people get well and stay well naturally, boosting their biological performance. There are various types of enzymes and usually, a specific enzyme is responsible for a particular chemical reaction only.
Even though they are produced by almost all living cells, cells in the liver, gallbladder, and pancreas, are mainly responsible for the production of metabolic enzymes.
Once the reaction is complete, the enzyme remains the same, but the substrate transforms to products. The substrate will fit into the active site perfectly, and the reaction between them takes place. This theory too supports the lock and key hypothesis that the active site and substrate fits perfectly and their shapes are complementary. Once the temperature rises above this level, the enzymes get denatured and they are no longer fit for reaction with substrates. Amylase in your saliva begins to break down carbohydrates. As food passes into your stomach, proteins are worked on by protease. The enzyme and the substrate do not react with one another; rather, the enzyme brings down the amount of energy needed for the reaction to occur, the activation energy. Because they are surrounded by intercellular air pockets, the mesophyll cells are able to perform a gas exchange when the stomatal pores in the leaf's epidermis open. Several chemical reactions take place inside each and every cell, and these reactions are crucial for the survival of the organism. While most of them are associated with metabolic processes like digestion and breathing, there are some, which are related to blood clotting, healing of wounds, controlling production of hormones, and destroying pathogens and environmental toxins.

Digestive enzymes are involved in chemical reactions that break down the food we eat and convert them into energy. For example, the enzyme sucrase acts upon the substrate sucrose to form products - fructose and glucose.
Enzymes in laundry detergents are responsible for removing the stains and make the clothes clean.
Once consumed, your meal begins a complicated, multiphase journey of breakdown and conversion into nutrients.
From there, the bolus of food passes into your small intestine, where lipase begins to break down fats, and amylase finishes off the carbohydrates. This applies to unicellular organisms too, wherein numerous chemical reactions are carried out by the single cell. With negative feedback, the end product of the reaction will fit into another site of the enzyme and inhibit its activity. Now can you imagine the innumerable chemical reactions that are carried out inside a human body, which has thousands of cells?
The enzymes of the digestive tract include pepsin, trypsin, and peptidases, which break down proteins into amino acids.
The course of action of enzymes are different and complex and so, there are various theories regarding this subject. As per this theory, the amino acids (in unbound state) at the active site are responsible for its specific shape. Variations from that pH level may slow down the activity of enzymes and very high or low pH results in denatured enzymes that cannot hold the substrate properly. Digestive enzymes help you breakdown food into smaller parts that can be absorbed, transported, and utilized by every cell of your body. Most of these chemical reactions that occur inside the cells are facilitated by the action of enzymes. Another digestive enzyme called amylase breaks down starch into simple sugars and lipase breaks down fat into glycerol and fatty acids. The rate of enzymatic activities may increase with the concentration of enzymes and substrates.
The body gets food enzymes from the food we eat or through consumption of enzyme supplements.
The enzyme called cellulase, which is responsible for digesting fibers is not produced by the body. While some enzymes help to break down molecules, some others are meant for merging small molecules to form large ones.

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