Where is the herpes virus found when it is dormant 39,energy bills usa 94,irs energy saving home improvements - Good Point

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Researchers from Carnegie Mellon University measured, for the first time, the pressure inside human herpes simplex virus 1 proving a long held theory that herpes viruses were packaged so full of genetic material that they built up high internal pressure allowing them to shoot viral DNA into a host cell during infection.
Professor Alex Evilevitch from the Carnegie Mellon University  and his team recently published their findings regarding the way the herpes virus injects genetic material into healthy cells on the Journal of the American Chemical Society.
The HSV-1 virus contains double-stranded DNA that is 400 times longer than the radius of the virus itself. More information on professor Evilevitch reaserch can be found on the Carnegie Mellon University  website. This editable Main Article is under development and not meant to be cited; by editing it you can help to improve it towards a future approved, citable version.
The herpes simplex virus is one of the herpes, DNA viruses that are important in causing human disease.
It is "composed of an inner core containing linear double-stranded DNA, surrounded concentrically by an icosahedral capsid of approximately 100 nm, an amorphous layer termed the tegument, and an outer envelope composed of lipids and glycoproteins." (Paula W. Using the Baltimore classification (which is based on the mechanism of mRNA production) is a Group 1 virus (dsDNA) from the family Herpesviridae, subfamily Alphaherpesvirinae, Genus Simplexvirus and Species Herpes simplex virus 1.
Herpes can be found throughout human history by reading texts from the past that describe the characteristics of the fever blisters.
In addition to affecting the oral and genital areas of the body, HSV can infect other areas. In this research experiment, Becket Feierbach and his associates looked to determine how HSV-1 develops spatial compartments within the host's nucleus where replication takes place. The third research article I found dealt with a possible vaccine that is being developed to prevent being infected with HSV-2.


Feierbach B, Piccinotti S, Bisher M, Denk W, Enquist LW (2006) Alpha-Herpesvirus Infection Induces the Formation of Nuclear Actin Filaments . Herpes simplex is a viral infection caused by the herpes simplex virus that can cause either affectation of the oral region, the genital region, or both. Genital herpes is typically asymptomatic, but when symptoms do occur manifestation include the presence of clusters of blisters and lesions on the external genitalia.
A cure for the virus is yet to be found, however, sores can usually heal on their own without treatment. According to the researchers this new discovery opens a door for developing new drugs and antiviral therapies to fight the herpes virus which effects almost 60% of U.S. With worldwide infection rates of HSV-1 and HSV-2 viruses estimated at between 65% and 90% of the global population it has reached epidemic proportions. This creates enormous pressure  which is the way the HSV-1 infects the cell nucleus after entering the cell itself. We can now hope that Evilevitch’s research will indeed be a first important step on the way to a new type of broad antiviral therapies.
The disease is contagious and can be transmitted through direct contact with infected lesions or body fluids, as well as through sexual contact with an infected individual. The virus is passed through contact with infected lesions and body fluids; genital herpes in particular is passed through sexual contact. Maybe the main reason why Herpes isn’t getting the attention it deserves is the fact that many people who are infected are described as asymptomatic or basically individuals who show no symptoms. They target molecules essential to the replication cycle of specific viruses, so each medication is designed to treat only one type of viral infection.


For years scientists hypothesized that a high internal pressure inside viruses like HSV-1 enabled them to shoot DNA into the host cell’s nucleus. Herpes simplex is a potentially life-threatening condition especially in newborns or in persons with compromised immune systems.
Antiviral drugs such as acyclovir, famciclovir, and valacyclovir are types of prescription antiviral medicines that come in both topical and oral forms to help with the symptoms of herpes. Additionally, since viruses mutate over time, they can become less susceptible to targeted medications.
However it was impossible to measure HSV-1’s internal pressure until the recent experiment by Evilevitch and his team. Herpes is considered contagious and it can be sexually transmitted, including contact with saliva or via contact with an infected area of the skin during re-activations of the virus. Iddo was awarded the 2006 Bar Hillel philosophy of science prize for his work on the relationship between science and technology. He is a member of the board of the lifeboat foundation and was the editor of several high-profile science and technology websites since 1999. Haser of at the University of Pennsylvania School of Medicine discovered such a protein that is produced during latency and its purpose.



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