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Author: admin | 05.01.2014 | Category: Tinnitus Hearing Loss

Tens of millions of Americans "hear" ringing, buzzing or humming in their ears -- an annoying and sometimes disabling condition known as tinnitus. Now, University of Michigan Medical School researchers report new scientific findings that help explain what is going on inside these unquiet brains. That area, called the dorsal cochlear nucleus, is the first station for signals arriving in the brain from the ear via the auditory nerve. Shore, who leads a lab in U-M’s Kresge Hearing Research Institute, is a Professor of Otolaryngology and Molecular and Integrative Physiology at the U-M Medical School, and also Professor of Biomedical Engineering, which spans the Medical School and College of Engineering. She explains that in tinnitus, some of the input to the brain from the ear’s cochlea is reduced, while signals from the somatosensory nerves of the face and neck, related to touch, are excessively amplified. The new findings illuminate the relationship between tinnitus, hearing loss and sensory input and help explain why many tinnitus sufferers can change the volume and pitch of their tinnitus’s sound by clenching their jaw, or moving their head and neck. But it’s not just the combination of loud noise and overactive somatosensory signals that are involved in tinnitus, the researchers report. Tinnitus especially affects baby boomers, who, as they reach an age at which hearing tends to diminish, increasingly experience tinnitus. Loud noises and blast forces experienced by members of the military in war zones also can trigger the condition.
Researchers still don’t understand what protective factors might keep some people from developing tinnitus, while others exposed to the same conditions experience tinnitus. Shore is now working with other students and postdoctoral fellows to develop a device that uses the new knowledge about the importance of signal timing to alleviate tinnitus.


But, she notes, any treatment will likely have to be customized to each patient, and delivered on a regular basis.
Funding: The research was supported by National Institutes of Health grants DC004825 and P30 DC05188.
One of U-M’s top priorities is to help spur economic development through a rich variety of programs in entrepreneurship, tech transfer, venture creation, business engagement, research, and education. Already, the U-M team has a patent pending and device in development based on the approach.
Though the work was done in animals, it provides a science-based, novel approach to treating tinnitus in humans. But it’s also a center where “multitasking” neurons integrate other sensory signals, such as touch, together with the hearing information. They hope to bring science-based approaches to the treatment of a condition for which there is no cure – and for which many unproven would-be therapies exist.
The condition most commonly occurs with hearing loss, but can also follow head and neck trauma, such as after an auto accident, or dental work. This is similarly the case with humans -- not everyone with hearing damage ends up with tinnitus. The device will combine sound and electrical stimulation of the face and neck in order to return to normal the neural activity in the auditory pathway. Shore’s device project is funded by the Coulter Translational Research Partnership, which is supported by the Wallace H.


You are free to copy, distribute, adapt, transmit, or make commercial use of this work as long as you attribute the University of Michigan Health System as the original creator and include a link to this article. Instead, even in a quiet room, they hear a constant ringing, buzzing, hissing, humming or other noise in their ears that isn’t real. An important finding in the new paper is that animals that did not get tinnitus showed fewer changes in their multisensory plasticity than those with evidence of tinnitus.
A study published in Occupational and Environmental Medicine reported that regular use of a mobile or cell phone appears related to chronic tinnitus. As always, the best approach is discussing options with your physician.Stop the NoiseWhen I was younger, predictions of hearing loss centered on that old time rock-n-roll. This report of the dangers of cell phones joins a recent report of hearing loss in teenagers. Many attribute teenage hearing loss to the loud music pumped in their ears through earbuds.



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