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Author: admin | 23.02.2014 | Category: Tinnitus Hearing Loss

The aim of this work is to compare the effectiveness of intratympanic therapy of gentamicin versus steroids in the treatment of Meniere’s disease in terms of symptomatic control and audiovestibular changes. Thirty patients with intractable unilateral Meniere’s disease were included in our study. IT therapy, whether gentamicin or dexamethasone, is an effective way to treat intractable Meniere’s disease, with very little side effects. Both groups showed 80–86% satisfactory control of vertigo by 6 months of follow-up, which increased to 100% by 1 year. When considering complete control of vertigo, IT gentamicin produces better results than dexamethasone. Intratympanic dexamethasone, intratympanic gentamicin, and endolymphatic sac surgery for intractable vertigo in Meniere’s disease. The first group was administered intratympanic (IT) gentamicin and the second group was administered IT dexamethasone.


IT dexamethasone leads to greater improvement in tinnitus than gentamicin, but not significantly. We followed our patients with respect to three main symptoms including vertigo, which was determined by the number and duration of attacks, and the class according to AA-HNS 1995 guidelines. We also assessed tinnitus and aural fullness in addition to the Dizziness Handicap Inventory. Also, we found a significant difference in the rate of hearing loss between both the groups in the high frequencies as gentamicin produced more deterioration in the hearing threshold than dexamethasone. Audiological assessment included pure tone audiometry, the speech reception threshold, and the speech discrimination score.
However, the dexamethasone group showed a significant improvement in hearing at low frequencies much more than the gentamicin group.
Vestibular assessment included the caloric test, rotatory chair stimulation, and vestibular evoked myogenic potential.


In terms of vestibular testing, we found that gentamicin significantly affected the phase parameter in the rotatory chair test and it also increased the canal paresis in caloric testing. We did not find any significant correlation between control of vertigo and any of the vestibular tests. Acupuncture , heat , electrical stimulation channels of energy , body's internal organs, correct imbalances digestion, absorption, and energy production activities, circulation of their energy . Specialization, Materia Medica, internal medicine, diagnosis , examine, refer ,investigations .health shops, pharmacies, prescription, complex remedies, labelled ,individualized ,mental, migraines, asthma, eczema, hay fever, glandular fever, chronic fatigue syndrome. Free-radical, toxin-, inflammatory, degenerative diseases, Nutrients, minerals, enzymes, vitamins, amino acids.



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