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Author: admin | 07.09.2013 | Category: Treatment For Ear Ringing

Vohwinkel syndrome: A genetic disorder characterized by hearing loss and thickened skin, particularly on the knuckles. The thickening of the skin (hyperkeratosis) can be "mutilating" and cause autoamputation of the digits.

The mutation is the replacement of aspartic acid with histidine at position 66 in the protein's chain of amino acids.

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