Cholesterol lowering medication and weight loss,best and healthiest way to lose weight and keep it off,ways to lose weight fast without running - Easy Way

02.07.2015
A new study looking at calcium scoring CT scans concluded that this special kind of X-ray can reclassify half of these 45 million people as being so low risk that they can avoid potentially unnecessary treatment with statins. This new information suggests that the scan may actually save insurance companies a lot of money by limiting overtreatment with statins.
People with borderline cholesterol values, who have been told they need statins, but have never had a heart attack, stent or bypass.
Perhaps these new insights into the value of these CT scans for certain patients could even help convince insurance companies to begin to cover the cost of calcium scoring.
Dr Mark Hyman can be followed on a number of the most popular social networks, click on any of the links below to keep up to date! If you are a post-menopausal women with high cholesterol, your doctor will almost certainly recommend cholesterol lowering medication or statins.
Since diabetes is a major cause of heart disease, this study calls into question current recommendations and guidelines from most professional medical associations and physicians.
Take it if you already have had one, but beware if your doctor recommends it for you if have never had a heart attack. This current study adds to an increasing body of literature questioning the benefits of statins, while highlighting their potential risks.
This study examined the data from the large government sponsored study called the Women’s Health Initiative, the same study that disabused us of the idea that Premarin prevented heart attacks in postmenopausal women. In fact, based on this randomized controlled trial, estrogen replacement therapy, once considered the gold standard of medical care for the prevention of heart disease, was relegated to the trash bin of history joining medicine’s many other fallen heroes including DES, Thalidomide, Vioxx, Avandia, and more. In this new study researchers reviewed the effect of statin prescriptions in a group of 153,840 women without diabetes and with an average age of 63.2 years. During the 3-year period of the study, 10,242 new cases were reported – a whopping 71 percent increase in risk from women who didn’t take statins.
But in a typical “my mind’s made up, don’t confuse me with the facts” statement by the medical establishment, the researchers said we should not change our guidelines for statin use for the primary prevention of heart disease. In a large meta-analysis published in the Lancet last year, scientists found that statins increased the risk of diabetes by 9 percent. Other studies have recently called into question the belief that high cholesterol levels increase your risk of heart disease as you get older.
A recent study showed that in healthy older persons, high cholesterol levels were associated with lower non-cardiovascular-related mortality.
The pharmaceutical industry, medical associations, and academic researchers whose budgets are provided by grants from the pharmaceutical industry continue to preach the wonders of statins, but studies like these should have us look good and hard at our current practices.
Cardiologists recommend putting statins in the water and giving them out at fast food restaurants and having them available over the counter. Recently, the Cochrane Group did a review of all the major statin studies by an international group of independent scientists. It was the JUPITER (v) trial that showed that lowering LDL (or bad cholesterol) without a reduction in inflammation (measured by C-reactive protein) didn’t prevent heart attacks or death. Mind you it wasn’t lowering the cholesterol that helped (which is the intended purpose of statins), but the fact that they lower inflammation. Yet other studies have shown no proven benefit for statins in healthy women (vii) with high cholesterol or in anyone over 69 years old.
In fact studies show that if you lower the bad (LDL) cholesterol in people with low HDL (good cholesterol) that is a marker of diabesity – the continuum of obesity, prediabetes and diabetes – there’s no benefit. Most people simply ignore the fact that 50-75 percent of people who have heart attacks have normal cholesterol. Some patients with multiple risk factors, or who have had previous heart attacks do benefit, but when you look closely the results are underwhelming. Despite the extensive data showing that statins are a questionable therapy at best, they are still the number one selling drug in the US. Yet somehow the 2004 National Cholesterol Education Program guidelines expanded the previous guidelines to recommend that even more people without heart disease take statins (from 13 million to 40 million) (xiii) What are we thinking? Why would respected scientists go against the overwhelming research that statins don’t prevent heart disease in people who haven’t already had a heart attack? The editorial that accompanies the recent study on women taking cholesterol-lowering medication that I opened this article with was quite clear. Remember what you put at the end of your fork is more powerful than anything you will ever find at the bottom of a pill bottle.
My new book The Blood Sugar Solution, which comes out at the end of February, gives exact details on what you should put at the end of your fork to prevent and reverse diabesity. Why do you think the medical establishment prescribes drugs that research shows don’t work? Please leave your thoughts by adding a comment below – but remember, we can’t offer personal medical advice online, so be sure to limit your comments to those about taking back our health! Mark Hyman, MD, believes that we all deserve a life of vitality—and that we have the potential to create it for ourselves. I am a 58 yr old female who has been a regular exerciser since the age of 26 and have been in good shape and good health. What were the trends in prescription cholesterol-lowering medication use in the United States?
What percentage of adults with a selected medical condition used a prescription cholesterol-lowering medication?
Did use of a prescription cholesterol-lowering medication vary among adults aged 40a€“64 with and without health insurance coverage?
During 2003a€“2012, the percentage of adults aged 40 and over using a cholesterol-lowering medication in the past 30 days increased from 20% to 28%. Cholesterol-lowering medication use increased with age, from 17% of adults aged 40a€“59 to 48% of adults aged 75 and over.
About 71% of adults with cardiovascular disease and 54% of adults with hypercholesterolemia used a cholesterol-lowering medication. Adults aged 40a€“64 with health insurance were more likely than those without health insurance to use a cholesterol-lowering medication. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States.
During 2011a€“2012, more than one-quarter (27.9%) of adults aged 40 and over reported using a prescription cholesterol-lowering medication in the past 30 days. For 2011a€“2012, 83% of adults who used a cholesterol-lowering medication reported using a statin alone, 10% used both a statin and a nonstatin, and 7% used only a nonstatin.
Among adults who used a prescription cholesterol-lowering medication, simvastatin was the most commonly used cholesterol-lowering medication, with 42% reporting its use. Slightly more than 70% of adults with doctor-diagnosed CVD reported taking prescription cholesterol-lowering medication in the past 30 days. During 2003a€“2012, there was a significant increase in the percentage of adults aged 40 and over who used a prescription cholesterol-lowering medication.
Prescription medication use: Survey participants were asked if they had taken a prescription medication in the past 30 days. NHANES is a cross-sectional survey designed to monitor the health and nutritional status of the civilian noninstitutionalized U.S. Cholesterol Treatment Trialistsa€™ (CTT) Collaborators, Mihaylova B, Emberson J, Blackwell L, Keech A, Simes J, et al.
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated. A recent study suggests the knowledge patients get from such testing can encourage lifestyle change, and even make patients more willing to use preventive medications such as statins. Some will also need a pill, but talk to your doctor about this test if you think you may be a candidate. David Becker is a board certified cardiologist with Chestnut Hill Temple Cardiology in Flourtown, Pa. The recommendation for women to take statins to prevent heart attacks (called primary prevention) may do more harm than good. If current guidelines were followed for those who should take statins, and people actually took them (thank God only 50 percent of prescriptions are ever filled by patients), there would be 3 million more diabetics in America.
For those over 85 it turns out having high cholesterol will protect you from dying from a heart attack, and, in fact, from death from any cause. This is extremely concerning because millions of prescriptions are written every day to lower cholesterol in the older population, yet no association has been found between higher cholesterol and heart disease deaths for those aged 55 to 84; and for those over 85, the association seems to be inverse — higher cholesterol predicts lower risk of death from heart disease.


These drugs frequently cause muscle damage, muscle cramps, muscle weakness, muscle aches, exercise intolerance (ii) (even in the absence of pain and elevated CPK – a muscle enzyme), sexual dysfunction, liver and nerve damage and other problems in 10-15 percent of patients who take them. Unfortunately, that research doesn’t get the benefit of billions of dollars of marketing and advertising that statins do. What is ignored by people who use this study to “prove” that statins work is the fact that there are so many better ways to lower inflammation than taking these drugs.
What isn’t so well known is that 75 percent of statin prescriptions are written for people who will receive no proven benefit.
Eight of the nine experts on the panel who developed these guidelines had financial ties to the drug industry.
If you have had a heart attack, or have heart disease, the evidence shows they do in fact help protect against a second heart attack, so keep taking them. However, you should be aware that most prescriptions for statins are given to healthy people whose cholesterol is a little high. We must treat causes – what we eat, how much we exercise, how we handle stress, our social connections and environmental toxins are all more powerfully linked to creating health and preventing disease than any drug on the market. Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)–can C-reactive protein be used to target statin therapy in primary prevention? Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study. That’s why he is dedicated to tackling the root causes of chronic disease by harnessing the power of Functional Medicine to transform healthcare. He is a practicing family physician, an nine-time #1 New York Times bestselling author, and an internationally recognized leader, speaker, educator, and advocate in his field. This was an increase from 2003a€“2004, when one in five adults used a cholesterol-lowering medication (19.9%) (Figure 1). Nearly 63% of adults with diagnosed diabetes and nearly 54% of adults with diagnosed hypercholesterolemia reported using a prescription cholesterol-lowering medication (Figure 4). In 2003a€“2004, one in five adults reported using a prescription cholesterol-lowering medication in the past 30 days. Those who answered a€?yesa€? were asked to show the interviewer the medication containers of all prescription medications. Heart disease and stroke statisticsa€”2014 update: A report from the American Heart Association. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: Meta-analysis of individual data from 27 randomised trials.
Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.
Total and high-density lipoprotein cholesterol in adults: National Health and Nutrition Examination Survey, 2011a€“2012.
Prescription cholesterol-lowering medication use in adults aged 40 and over: United States, 2003a€“2012. A new study in the Archives of Internal Medicine found that statins increase the risk of getting diabetes by 71 percent in post-menopausal women.
Today there are many, many more women taking statin medications, thus many more are at risk from harm from statins.
Statin prescriptions are handed out with religious fervor, but do they work to prevent heart attacks and death if you haven’t had a heart attack already? In addition, many other studies support this and point out the frequent and significant side effects that come with taking these drugs. One big trial was touted as proving statins work to prevent heart attacks, but the devil is in the details. The ENHANCE trial showed that aggressive cholesterol treatment with two medications (Zocor and Zetia) lowered cholesterol much more than one drug alone, but led to more arterial plaque and no fewer heart attacks. Sounds good, but that just means the risk of getting a heart attack goes down from 3 percent to 2 percent. Thirty-four other non-industry affiliated experts sent a petition to protest the recommendations to the National Institutes of Health saying the evidence was weak. Elevated blood cholesterol is a major risk factor for CVD, and statin therapy has been strongly associated with a reduced risk of atherosclerotic CVD (2,3). It is conducted by the Centers for Disease Control and Preventiona€™s (CDC) National Center for Health Statistics. Kit are with CDCa€™s National Center for Health Statistics, Division of Health and Nutrition Examination Surveys. 1988a€“2012 data documentation, codebook, and frequencies: Prescription medicationsa€“drug information. The risk of diabetes was 49 percent for white women, 57 percent for Hispanic women, and 78 percent for Asian women.
He is also the founder and medical director of The UltraWellness Center, chairman of the board of the Institute for Functional Medicine, a medical editor of The Huffington Post, and has been a regular medical contributor on many television shows including CBS This Morning, the Today Show, CNN, The View, the Katie Couric show and The Dr. The national cholesterol treatment guidelines outline the importance of using cholesterol-lowering medications for the prevention of coronary heart disease (4).
In 2011a€“2012, the majority of adults using a cholesterol-lowering medication reported using a statin alone (83%). Cholesterol-lowering medications were identified using the secondary level of drug category codes, specifically code 19. Data from NHANES 2003a€“2004 through 2011a€“2012 were used for trend analysis, and the most recent cycle of 2011a€“2012 data were further used for examining the patterns of cholesterol-lowering medication use.The NHANES sample is selected through a complex, multistage probability design.
Using National Health and Nutrition Examination Survey (NHANES) data, this report evaluates recent trends in prescription cholesterol-lowering medication use among U.S. Since then, thousands of patients have participated in the program, achieving significant results in improving cardiac wellness.
Sample weights, accounting for the differential probabilities of selection, nonresponse, and noncoverage, were used for analyses. Adults aged 40a€“64 who reported having health insurance or prescription medication coverage were more likely to take prescription cholesterol-lowering medications.Hypercholesterolemia or high cholesterol is one of the most common preventable risk factors for atherosclerotic CVD. Variance estimates accounted for the complex survey design using Taylor series linearization. In 2011a€“2012, more than 30 million Americans aged 20 and over (13%) had measured high total cholesterol (5).
Estimates for the total adult population aged 40 and over, for men and women, and for race and Hispanic origin subpopulations were age-adjusted by the direct method to the 2000 U.S. There is extensive and consistent evidence supporting the use of cholesterol-lowering medication, especially statins, in addition to lifestyle changes, to treat lipid disorders and reduce atherosclerotic CVD events. Time series estimates showed improved control of high total serum cholesterol over the past two decades in England and the United States. The 2013 cholesterol treatment guidelines updated recommendations for statin therapy on the basis of low-density lipid cholesterol levels and atherosclerotic CVD risks (6). Differences between groups were evaluated using a t statistic at the p less than 0.01 significance level (adjusted for multiple comparisons). As you suggested, I had my particle size checked and unfortunately these numbers were not good. To test for linear trends, the null hypothesis of nonlinear trend was examined using orthogonal polynomials.
Untreated high blood cholesterol represents a missed opportunity in the face of a global epidemic of chronic diseases. I will speak with my internist about it but would be interested in your opinion on the diabetes risk in relation to statins and particle size. Hyman or I would still be obtaining food from packages and who knows where the Zocor medication might have taken me.
La hipercolesterolemia sin tratar supone una oportunidad perdida, a tenor de la epidemia mundial de las enfermedades crónicas. The growing number of national health examination surveys that measure total serum cholesterol provides an opportunity to ascertain how well cholesterol-lowering medication is being delivered to populations at risk of cardiovascular disease.12 Using microdata from multiple national health examination surveys in eight countries, we have estimated the proportion of the population diagnosed with high total serum cholesterol, on treatment with cholesterol-lowering medication, and with evidence of therapeutic control. Individual-level data was downloaded from agency web sites when publicly available or obtained through formal application procedures and by contacting study authors. The guidelines of the United States Centers for Disease Control and Prevention and WHO were followed in all countries except Germany and Thailand, where national guidelines were observed.
Blood tests were performed in a central laboratory in all countries except Thailand, which relied on five regional university laboratories.
To determine whether countries are delivering cholesterol-lowering medication and effectively lowering blood cholesterol levels, we assigned all individuals with high total serum cholesterol to one of four mutually exclusive categories: undiagnosed, diagnosed but untreated, treated but not controlled, and treated and controlled.
This was done to ensure a standard population that reflected the rightward shift in age structure of the population with high total serum cholesterol levels. Data from the National Health and Nutrition Examination Survey III (NHANES) of the United States,20 conducted from 1988 to 1994, are shown in Fig.


1 as a time point for 1993 and treated as a comparator for the 1993 Health Survey for England.21 To account for possible variation in age structure between these countries over time, we age-standardized these time series cross-sectional rates to the population of the United States aged 40-79 with high total serum cholesterol in 2006.
3 shows figures for medication coverage and control of high total serum cholesterol for all surveys. 4 shows the proportions of people who were diagnosed, treated with cholesterol-lowering medication and successfully controlled, stratified by age and sex. The prevalence of undiagnosed high total serum cholesterol decreased with age in England, Japan and Scotland in both men and women, and only in men in the United States. These differences reached statistical significance in England for both sexes, and in Scotland for men. The prevalence of undiagnosed high total serum cholesterol differed significantly by sex for all age categories in Scotland and for individuals 55-79 years of age in England. The proportion of individuals who were diagnosed but untreated decreased with age in all countries except Germany, Jordan and Mexico. The proportion of individuals who were treated and achieved evidence of control increased with age in England among men and women and in Japan, Scotland and the United States among men alone. Control rates differed significantly by sex for all age groups in England and for individuals 55-79 years of age in Scotland. In both countries, the proportion of individuals diagnosed but untreated decreased, whereas the proportion who achieved therapeutic control increased steadily.
In essence, we assumed that any elevated blood cholesterol level below this cut-off represented the effect of lipid-lowering medication among those who were on treatment for very high total serum cholesterol. As expected, coverage estimates are highly sensitive to the definition of disease state and treatment goals. For instance, the limited use of cholesterol-lowering medication in Jordan and Thailand is alarming because high serum cholesterol is common among adults in both countries.
These findings support the growing recognition that cardiovascular diseases are not merely "diseases of affluence" and that some middle-income countries are beginning to face a double burden of both chronic and communicable diseases.26,27 Effective delivery of cholesterol-lowering medication has increased threefold in England and fivefold in the United States over the past two decades. Our analysis suggests that this is associated with the increased use of medication among the diagnosed population rather than an increase in the fraction of the population that is diagnosed. Thus, efforts to screen more people and make them aware of their high serum cholesterol levels have been less successful than efforts to deliver treatment to those who know they are hypercholesterolaemic. There are now over 100 manufacturers of this potent cholesterol-lowering medication, including many in China and India.30 In 2007, the drug was added to the WHO's list of essential medicines. In some regions, treatment with simvastatin (40 mg) and with lovastatin (20 mg) costs less than US$ 30 and US$ 3 per year, respectively.31 These changes have probably led to improved adherence to statins, as well as to broader screening and prescribing. Unfortunately, any analysis of the effect of treatment guidelines is confounded by the fact that physicians in certain countries have been shown to rely on differing guidelines, including those from other countries.34 Further work is required to determine the effect of cholesterol screening policy and of guidelines on the delivery of cholesterol-lowering medication.
The direct benefits of health reform efforts conducted in the past decade by the Mexican government have been difficult to establish.35 Cross-national comparisons among developing countries with similar disease burdens can reveal striking differences in health system investment. For example, Mexico and Thailand are similar in population size and in the prevalence of high serum cholesterol. However, Mexico invests more than twice as much as Thailand in physicians per capita, whereas Thailand spends twice as much as Mexico on medications.35 To further understand medication coverage in Mexico and indeed in all countries, more research into how health resources are allocated by governments to curb cardiovascular diseases is required. To assess diagnosis and medication use we relied on self-reported responses whose validity, reliability and comparability are unknown. All surveys enquired about a previous diagnosis of high blood cholesterol and medication use, but the phrasing of the questions was not identical. Because it was not possible to adjust for these differences, comparisons across countries may be confounded. These issues highlight the need to standardize health examination surveys to allow for more robust comparisons across countries and more frequent comparisons across time.
We had to limit our analysis to total serum cholesterol because this was the only biomarker common to all surveys.
Thus, it allowed us to cover all individuals who could reasonably be expected to receive cholesterol-lowering medication.
The association between blood cholesterol levels and cardiovascular risk is curvilinear and modified by the presence or absence of other risk factors.
Thus, there is no biological threshold for conferring high risk from blood cholesterol levels.44 Recommendations Programmes designed to achieve higher detection and control of high blood cholesterol should be developed and implemented. Dried blood spot technology offers a new and affordable approach to screening in low-income settings.45 At the same time, better chronic disease surveillance is needed to monitor and guide these programmes. The standardized chronic disease modules developed as part of WHO's STEPwise approach to surveillance are a good example, and similar modules emphasizing medication delivery require broader adoption. Finally, surveys should be repeated at regular intervals so that countries can track their progress towards achieving health goals, as England and the United States are doing.
These intervention coverage metrics will play an important role in reducing the burden of chronic diseases as global goals are increased beyond the current, highly conservative goal of a 2% decrease per year. The recent announcement of a Global Alliance for Chronic Disease is heartening and suggests that the global burden of cardiovascular diseases is beginning to be viewed with the same urgency formerly reserved for infectious diseases.
Cholesterol-lowering medication is widely available, highly effective and can play an essential role in reducing cardiovascular disease around the world.
Despite these facts, effective medication coverage for control of high cholesterol remains disappointingly low. The Mexico data analysed in this publication is from the National Survey of Health and Nutrition 2006, designed and conducted by Mexico's National Institute of Public Health. The original creators, depositors and copyright holders of the England and Scotland data and the UK Data Archive bear no responsibility for this analysis. Crown copyright material is reproduced with the permission of the Controller of HMSO and the Queen's Printer for Scotland. The sponsor had no role in the study design, data gathering and analysis, or in the interpretation or writing of this report.
The corresponding author had full access to all data and had final responsibility for the decision to submit for publication. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins.
World Health Organization (WHO) and International Society of Hypertension (ISH) risk prediction charts: assessment of cardiovascular risk for prevention and control of cardiovascular disease in low and middle-income countries. Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort.
Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and regional analysis on reduction of cardiovascular-disease risk. Prospects, problems, and prerequisites for national health examination surveys in developing countries. Evaluation of Health Interview Surveys and Health Examination Surveys in the European Union. Prevalence and management of prehypertension and hypertension by geographic regions of Thailand: the Third National Health Examination Survey, 2004.
Lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease.
A global survey of physicians' perceptions on cholesterol management: the From The Heart study. Cardiovascular prevention guidelines in daily practice: a comparison of EUROASPIRE I, II, and III surveys in eight European countries. Fatal and nonfatal cardiovascular disease and the use of therapies for secondary prevention in a rural region of India.
Dyslipidemia in primary care-prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS).
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research.




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