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21.03.2016
Metformin has long been used as medication for people diagnosed with diabetes, but a new study directs the drug towards another purpose: reduction of pancreatic cancer progression. This was revealed by a group of researchers from the Massachusetts General Hospital, who described the effect of the diabetes drug on pancreatic cancer. The most common form of this type of cancer is pancreatic ductal adenocarcinoma, which exhibits weight management issues on half of the people diagnosed with the disease.
The research team believes that although their study is not a complete solution to pancreatic cancer, their discovery on metformin could become a worthy addition to curing the disease. A new research has found that Metformin, a drug commonly used for treating diabetes, is appreciably effective against cancer too.
The study found that for women with type 2 diabetes and cancer, the odds of dying from cancer appeared to be 45 percent higher compared to women with cancer who didn’t have diabetes. Gong cautioned, however, that this study didn’t prove that metformin prevents or reduces the risk of dying from cancer, only that an association was found.
Metformin is a first-line drug in the treatment of type 2 diabetes, the American Diabetes Association (ADA) says. Looking at specific cancers, the risk for postmenopausal women with diabetes appeared to be about 25 percent to 35 percent higher for developing colon and endometrial cancers and non-Hodgkin lymphoma.
One diabetes expert who wasn’t involved with the study was cautious about interpreting the results. Although the study found a slight risk reduction, it depended on taking the drug for a long time, said Dr. The above conclusion was reached after analyzing more than 146,000 postmenopausal women with type 2 diabetes.
The study revealed that women with Type 2 Diabetes faced a 45% higher risk of mortality due to cancer as compared to diabetes-free women. Type 2 Diabetes or NonInsulin Dependent Diabetes is a condition in which the body is not able to utilize the insulin produced by pancreas efficiently. As per the guidelines issued by the American Diabetes Association (ADA), Metformin is the first drug of choice in Type 2 Diabetes Mellitus.
Medical data reveals that Diabetes in Post Menopausal women increases the risk of having colon and endometrial cancers and non-Hodgkin lymphoma by 25 percent to 35 percent. Experts, however, contend that the exact mechanism of the action of this age-old drug which has been used in Diabetes is still not clear. A commonly used diabetes drug, used to treat Type 2 diabetes, could have the potential to lower cancer death risks, a new study has found. Researchers found an association between Metformin and a lesser risk of cancer death when compared to other diabetes medications, writes Tech Times.
The association was particularly prevalent among postmenopausal women with type 2 diabetes. However, the researchers found that women with cancer, who took Metformin as part of their type 2 diabetes treatment had the same level of risk as those women with cancer, but without diabetes. Study lead author Zhihong Gong from Roswell Park Cancer Institute in New York says the results could suggest that metformin could be a better option for the treatment of type 2 diabetes treatment compared to other drugs prescribed for postmenopausal women with cancer.
The team analyzed data gathered from 1993 to 1993, which was taken from almost 146,000 postmenopausal women aged between 50 and 79 years old. The researchers found that the participants in the study had a 25 to 35 percent chance of developing colon and endometrial cancers.
According to Gong, the study suggests that diabetes-sufferers still bear a higher risk factor for cancer-associated death. A commonly prescribed drug for type 2 diabetes, Metformin, has been recently associated with a decrease in postmenopausal women dying from cancer.
According to the report from Doctors Lounge, researchers discovered that postmenopausal women with type 2 diabetes and cancer have 45 percent higher risk of dying compared to women with cancer but didn't have diabetes.
For the study, published in the International Journal of Cancer, researchers analyzed the data of 145,826 postmenopausal women between the ages of 50 and 79 from the Women's Health Initiative study conducted between 1993 and 1998. Type 2 diabetes, according to American Diabetes Association, occurs when the body does not use insulin properly.
In a previous report, the World Health Organization has urged a global action against diabetes after discovering that over 400 million people in the world have diabetes, 400 times higher compared to data collected in 1980. Rare Whale Vomit Considered As Floating Gold, Costs $70,000; Will It Endanger Sperm Whales?
NASA's First Inflatable Room Successfully Attaches To The ISS; 'Space Hotels' A Possibility? A popular type 2 diabetes drug metformin has been linked to lower risk of death among postmenopausal women with type 2 diabetes after analysis of medical data collected under the large Women's Health Initiative study.
The study team found that women who were prescribed metformin for type 2 diabetes, had almost the same risk of dying from cancer compared to women who were diabetes free. The study simply suggests that there is an association between lower risk of death and intake of metformin among postmenopausal women with type 2 diabetes.
The study was led by Zhihong Gong, assistant professor of oncology at the Roswell Park Cancer Institute, in Buffalo, N.Y. For postmenopausal women with diabetes, the risk of developing colon or endometrial cancer was 25-35 percent higher compared to women who were diabetes free.


A UPI report informed, “Metformin is a first-line drug in the treatment of type 2 diabetes, the American Diabetes Association (ADA) says. Metformin, marketed under the tradename Glucophage among others, is the first-line medication for the treatment of type 2 diabetes. It is not allowed to reproduce, copy or translate a part or parts of the content on Maine News Online website. Postmenopausal women with type 2 diabetes were found to have lower risk of death from cancer after taking a popular type 2 diabetes medication metformin. The study team noticed that women with type 2 diabetes had nearly 45 higher risk of death due to cancer compared to diabetes-free women. As per medical records, diabetes among postmenopausal women raises the risk of developing colon and endometrial cancers and non-Hodgkin lymphoma by 25 percent to 35 percent. People with type 2 diabetes don't use the hormone insulin efficiently, which leads the pancreas to pump out more and more insulin until it eventually fails.
The study team reviewed data from 145,826 postmenopausal women between the ages of 50 and 79. The encouraging findings of the study published in the April 15th print edition of the prestigious International Journal of Cancer. According to a report in Nature World News by John Raphael, "The researchers looked at specific kinds of cancer.
A diabetes drug called Metformin was found to have the potential to cut cancer death risks, a new study has found. The association between the type 2 diabetes medicine and risk of cancer death was particularly seen among postmenopausal women with type 2 diabetes. More specifically, the team found that women with both cancer and type 2 diabetes have a 45 percent more chance of dying from cancer than those who have cancer but does not have diabetes. A striking finding though is that women with cancer, who took Metformin for type 2 diabetes treatment had the same risk of dying as those without diabetes at all.
Study lead author Zhihong Gong from Roswell Park Cancer Institute in New York says the results may provide evidence that it may be more beneficial to use metformin as type 2 diabetes treatment than other drugs for postmenopausal women who have cancer.
The team analyzed data of almost 146,000 postmenopausal women aged between 50 and 79 years old from 1993 to 1998. The participants had a 25 to 35 percent risk of developing colon and endometrial cancers, as well as non-Hodgkin lymphoma. Gong says these results suggest that diabetes is still a risk factor for cancer and cancer-associated death. Although the study yielded interesting results that may provide a promising basis for future treatments, it is not high time to get absolutely excited, yet. Gong agreed, saying that the study was not able to prove that Metformin really prevents or reduces cancer deaths.
Ultimately, further studies are needed to ascertain the potential role of the drug to cancer death risk. T-Mobile Releases Android 6.0 Marshmallow Updates For Galaxy S6 And S6 Edge, What About AT&T? Metformin, meanwhile, is being taken by type 2 diabetes patients to help them control their weight.
Results revealed that tumor-associated macrophage levels in the lab rats were decreased by 60 percent. But, in women with cancer who took metformin to treat their type 2 diabetes, the risk of dying from cancer seemed about the same as it was for women without diabetes. And, she added that more studies are necessary to figure out metformin’s possible role in decreasing the risk of dying from cancer. People with type 2 diabetes don’t use the hormone insulin efficiently, which leads the pancreas to pump out more and more insulin until it eventually fails, the ADA explains.
So, in an effort to exclude women with type 1 diabetes, the researchers removed information on anyone who had been diagnosed with diabetes before age 21. The women’s risk was more than doubled for liver and pancreatic cancers, the researchers found. Joel Zonszein, director of the Clinical Diabetes Center at Montefiore Medical Center in New York City. The study further revealed that women suffering from Type 2 Diabetes, who took Metformin regularly had the same risk of dying from cancer as women who is diabetes free.
Liver and Pancreatic cancer risk are also twice higher in Diabetic women as compared to nondiabetic women. However, the paper has revealed that the drug has a role to play in reducing mortality or increasing life expectancy in postmenopausal women who is suffering from Type 2 Diabetes and cancer. Researchers found that women with both cancer and Type 2 diabetes had a 45 percent higher chance of dying from cancer compared to those with cancer, but not diabetes.
While the study could provide evidence for future treatments, it does not prove that Metformin is responsible for the prevention or reduction of deaths from cancer.
All rights reserved.Medical Daily is for informational purposes and should not be considered medical advice, diagnosis or treatment recommendation. They also found out that there is no significant difference in the mortality rate of women with cancer being treated with Metformin for their type 2 diabetes and those who have cancer but without diabetes.


They discovered that postmenopausal women with diabetes have 25 to 35 percent increased risk in developing colon and endometrial cancers and non-Hodgkin's lymphoma while the risk for developing liver and pancreatic cancer are being doubled. The treatment for type 2 diabetes with lifestyle changes, oral medications such as the Metformin and insulin injections. Women with type 2 diabetes and cancer have 45 percent higher risk of dying from cancer compared to women who don’t have diabetes. The study team has indicated that it should be concluded that metformin prevents or reduces the risk of death due to cancer. Further study will be required to see the impact of metformin and how it helps in reducing the risk of death from cancer among diabetes patients. The study findings have been published in the April 15 issue of the International Journal of Cancer. People with type 2 diabetes don't use the hormone insulin efficiently, which leads the pancreas to pump out more and more insulin until it eventually fails, the ADA explains. Joel Zonszein, director of the Clinical Diabetes Center at Montefiore Medical Center in New York City, said, “We still don't understand the exact mechanism of action of this old drug used in diabetes.
The study team reached the conclusion after analyzing medical data for 146,000 postmenopausal women with type 2 diabetes and the data was collected between year 1993 and 1998. The team found that women who were regularly taking metformin had almost the same risk of dying from cancer as women who were diabetes free.
The risk of liver and pancreatic cancer was also higher by twice compared to women who were diabetes free. Metformin is a first-line drug in the treatment of type 2 diabetes according to the American Diabetes Association (ADA). The information was collected between 1993 and 1998 and came from the Women's Health Initiative study. Another notable finding is that Metformin therapy may have a more significant role in managing diabetes-associated cancers than other anti-diabetes treatments. Joel Zonszein from Montefiore Medical Center in New York says the study showed that the effects depend on the long-term administration of the drug. Insulin is a hormone that’s necessary for the body to use the carbohydrates in food as fuel.
The information was collected between 1993 and 1998 and came from the large Women’s Health Initiative study. More studies are in progress to determine the long-term effect of metformin in cancer risk, he added. It has been revealed that women with Type 2 Diabetes and Cancer have a higher chance of death due to cancer as compared to women who are free from diabetes. The records were collected between 1993 and 1998 under the large Women's Health Initiative study. Insulin is a hormone that's necessary for the body to use the carbohydrates in food as fuel.
Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.
Women with type 2 diabetes and cancer, have higher risk of death due to cancer compared to women who are free from diabetes. We value your privacy and we will never sell or distribute your email or personal data to third party advertisers.
Metformin makes the body more sensitive to insulin and reduces insulin resistance, the researchers said. Under the HoodBehavior, Neuroscience & Your Brain Overcoming Stress And Anxiety Can Literally Save Your Life On National Stress Day 2016, take a step back to review the ways in which you can prevent your stress from damaging you permanently. InnovationTechnology & the Business of Medicine We Finally Know How Mother-To-Child Virus Transmissions Affect Fetal Development Viruses like Zika and cytomegalovirus can harm developing fetal brains, and researchers have discovered a key to why.
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In an effort to exclude those with type 1 diabetes — a condition in which the pancreas produces little to no insulin, and is usually diagnosed in children — they excluded those who had been diagnosed with the condition before age 21.In addition to an elevated risk of liver and pancreatic cancer, the participants also had a 25 to 35 percent higher risk of developing colon and endometrial cancers, as well as non-Hodgkins lymphoma.



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