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En poursuivant votre navigation sur ce site, vous acceptez l’utilisation de Cookies, utilises pour des besoins de statistiques et d'affichage. Restez connectes a toute l’actualite sante du monde en vous inscrivant a notre newsletter ! The Food and Drug Administration (FDA) recently approved Qsymia (phentermine and topiramate extended release) and Belviq (lorcaserin hydrochloride) weight loss pills for management of obesity. 62%-69% of patients that received Qsymia lost an average of 5% body weight in comparison to 20% that received placebo.
In patient without type 2 diabetes, 47% lost an average of 5% bodyweight compared to 23% on placebo.
In patient with type 2 diabetes, 38% lost average 5% of bodyweight compared to 16% in placebo. The epidemic of obesity threatens the overall wellbeing of patients, especially for those with co-morbidities.
The material on this site is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. The content on this website is for information only and is not a substitute for professional medical advice, diagnosis, and treatment. PlayIn this video, Dr William McCarthy, a specialist in non-surgical weight loss medicine, describes some of the barriers many people experience as they try to lose weight. Qsymia does have some serious side effects and is not to be taken by women who are pregnant. In the beginning, the manufacturer of Qsymia does not expect very many private or public insurance plans to pay for prescriptions for the drug.
At the current time, Vivus has negotiated with the FDA a risk-reduction plan where Qsymia will only be available to physicians who have finished a Qsymia provider training course. Thanks for reading and to continue to read my articles, please click subscribe just above the comments section. Charlotte RaynorSpringfield Women's Health ExaminerCharlotte Raynor is a freelance writer living in Decatur, Illinois with her four dogs and leopard gecko. Kate Middleton Royal Tour of India : The Duchess of Cambridge style guide Kate Middleton wore several stylish outfits during her recent Royal visit to India. The FDA went on to say that Qsymia should not be used during pregnancy, as topiramate, one of the two components of the drug, can cause harm to the fetus, increasing the risk of oral clefts during the first trimester. The second component of the drug, the diet medication phentermine, is used for a limited period of time to speed weight loss in overweight people who are exercising and eating a low-calorie diet, according to the National Institutes of Health (NIH). Other side effects of the drug include tingling of the hands and feet, dizziness, insomnia, constipation, altered taste sensation, and dry mouth.
A new weight-loss pill that many doctors consider the most effective of a new generation of anti-obesity drugs got the approval of the Food and Drug Administration on Tuesday. The pill, called Qsymia, was approved for patients who are overweight or obese and also have at least one weight-related condition such as high blood pressure, diabetes or high cholesterol.
The drug offers hope for those who have failed to lose weight in other ways, but its path to approval also underscores how difficult it has been for drugmakers to find obesity treatments that are safe and effective.

The drug's maker, Vivus Inc., said it plans to bring the drug to market in the fourth quarter of this year. In testing, the drug made led patients to lose more weight than two other weight-loss pills recently review by the FDA.
Despite its impressive performance in clinical trials, Qsymia is not exactly a scientific breakthrough. Phentermine is a stimulant that suppresses the appetite, and has long been used for short-term weight loss. Researchers say the innovation of Qsymia lies in targeting more than one of the brain signals that drive people to overeat. Qsymia is the second weight-loss drug approved by the FDA in less than a month, following Arena Pharmaceutical's pill Belviq in late June. The FDA's approvals of Qsymia and Belviq suggest a new willingness to make weight-loss medications available, even in the face of lingering safety issues.
The FDA initially rejected Vivus' drug in 2010 over concerns that it can cause birth defects if taken by pregnant women. The agency also said patients with recent or unstable heart disease or stroke aren't good candidates for the drug because its effect on heart rates in those patients is not known. Analysts estimate the new pill could garner more than $1 billion in sales by 2016, though Mountain View, Calif.-based Vivus plans a slow rollout. Both Qsymia and Belviq are combined with a reduced calorie diet and exercise for long term weight management in adult patients with a body mass index (BMI) of 30 or greater or adult overweight patients with at least one weight related condition such as high blood pressure, type II diabetes, or high cholesterol.
The first component is a migraine and seizure medication called topiramate that causes weight loss by reducing appetite, increasing feelings of fullness, reducing the taste of food, and increasing burning of calories.
Belviq possibly decreases food consumption by making a person feel full even after consuming less food than usual. With the FDA approval of Qsymia and Belviq weight loss pills, patients who are obese can potentially benefit from these two therapies. 18, 2012, was the first day that the new weight loss pill, Qsymia, was available for sale from certain certified mail-order pharmacies.
However, the company intends to try to get Qsymia added to the insurance company's formularies as soon as possible.
She graduated from Colorado Technical Academy with an Associate of Science Degree in Medical Coding and Billing in 2010. Topiramate, which is also known as Topamax, is an anti-convulsant and is used to treat seizures in people who have epilepsy. The drug is actually a combination of two older drugs long known to help with weight loss: phentermine and topirimate. Topiramate is an anticonvulsant, sold by Johnson & Johnson as Topamax, that makes people feel more satisfied after eating. The cocktail of phentermine and fenfluramine was a popular weight-loss combination prescribed by doctors, though it was never approved by the FDA. In 2010, Abbott Laboratories withdrew its drug Meridia after a study showed it increased risks for heart attack and stroke.

The agency laid out a risk-management plan Tuesday specifically designed to minimize the chance of the women becoming pregnant while using the drug. Company executives say their initial marketing efforts will focus on obesity specialists, not general doctors. However, FDA regulators ordered the company to change the name to avoid potential confusion with similar-sounding drugs. This article will highlight some distinguishing facts about the two medications so that patients and physicians can make an informed decision when selecting a weight loss pill. The second component is called phentermine, which suppresses appetite by triggering the release of a brain chemical (hormone) called leptin, which regulates appetite.
It may work by increasing levels of serotonin, a neurotransmitter (brain chemical) that nerves use for communicating. Discontinue therapy if a patient has not lost at least 5% from baseline bodyweight by week 12. However, important practices and monitoring is extremely critical to ensure the safety and efficacy of both medications. According to Vivus Pharmaceuticals, Qsymia- pronounced kyoo-SIM-ee-uh is the first weight loss medication to go to market in 13 years. For safety's sake, women of childbearing age must prove that they are using birth control before a prescription will be given for Qsymia. Currently, Walgreens, CVS and Kaiser Permanente (for Kaiser members only) are the only certified pharmacies that can fill Qsymia prescriptions. The company said patients on the strongest formulation tested lost nearly 11 percent of their weight. But a long line of prescription diet pills have been associated with dangerous side effects, particularly heart problems. It recommends that women of childbearing age test negative for pregnancy before starting the drug and take a monthly pregnancy test while taking it.
A third California drugmaker, Orexigen Therapeutics Inc., is still running clinical trials of its product, Contrave, and is working toward an FDA approval date in 2014.
To dispense Qsymia, pharmacies and prescribers must be certified through special training and a Risk Evaluation and Mitigation Strategy (REMS) program must be followed. Some other possible side effects noted are suicidal thoughts or actions, increased heart rate and eye problems.
With Belviq, patients dropped from 220 to 207 pounds; on Qsymia, patients lost 10 more pounds, dropping from 227 to 204. Some physicians feel that it is an important day in the lives of obese people for whom this drug might help.

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