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admin | Cure Bv Naturally | 13.12.2015
Learn latest Asthma Treatment with Asthma Symptoms, Causes, Prevention and Pathophysiology.
Asthma is chronic inflammatory disease of the airways and it is common in almost all populations. WHO Asthma Factsheet shows that there are around 235 million asthmatic patients in the world. The strongest risk factors for developing asthma are inhaled substances and particles that may provoke allergic reactions or irritate the airways.
Asthma diagnosis depends upon pattern of symptoms, response to therapy over time and spirometry.
Asthma Sign and Symptoms may vary from case to case due to different underlying cause o asthma.
Asthma was first recognized in Ancient Egypt and it was treated by drinking a mixture known as kyphi.
In 1880 the use of intravenous doses of a drug called pilocarpin was included in the treatment of asthma.
Many environmental factors act as trigger for the development and exacerbation of asthma including allergens, air pollution, and other environmental chemicals. Family history is very major Factor in genetic predisposition of asthma, with many different genes being implicated. Viral infections may also act as triggers of asthma exacerbations, it is not clearly understood how they play a role in pathophysiology. Asthma is basically inflammation of the airways which results in bronchoconstriction of the surrounding smooth muscles. Typical changes in the airways include an increase in eosinophils and thickening of the lamina reticularis which an indication of inflammatory response.
Methylxanthines or methylated xanthines cause bronchodilation of air way by relaxing bronchial smooth muscle and helps the constricted airways to dilate.
The mechanism of action of methylxanthine is not clearly understood but it is observed that methylxanthines inhibit the enzyme phosphodiesterase, which decrease the level of cyclic AMP(CAMP). This cylic AMP will in turn decrease the constriction of smooth muscles and causes relaxation of smooth muscles of respiratory tract. Methylxanthines are bronchodilators used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Main mechanism of these agents is that they stimulate beta -2 receptors that are present on bronchial smooth muscles and responsible for constriction or relaxation of smooth muscles.
Long acting beta adrenoceptor agonists are used in patients with chronic type of asthma or having asthma problem for a long time. Corticosteroids are also used in the management and asthma treatment due to their anti inflammatory action.
Asthma Treatment with anti cholinergic drugs is very effective in asthmatic condition because of their beneficial effect in asthma and other pulmonary diseases. Avoidance of causative factors is a key of improving control and preventing attacks of asthma. Asthma can be prevented by proper immunization of influenza annually and using face mask to avoid inhalation of allergens. Moreover, vaccination of pneumonia is also necessary to decrease the risk of asthma in future. Arslan Malik is noted health blogger, public health activist, aspiring dreamer and avid reader. Ebola outbreak in the present year 2014 is considered to be the largest outbreak of Ebola as per the World Health Organization (WHO) which has declared it an international emergency. Ebola virus disease which was previously known as Ebola hemorrhagic fever, is a fatal illness having a death rate of up to 90% and is caused by Ebola virus. The early symptoms of Ebola virus infection are tough to detect as that resemble the symptoms of many other common diseases like flu, infections, typhoid, cholera etc. It is now clear that Ebola disease is caused by virus from the Filoviridae family, commonly known as Ebola virus. Contact with blood, secretions, organs or other bodily fluids (stool, urine, saliva, semen) of a person who is infected with Ebola virus.
Contact of broken skin or mucous membranes of a healthy person with contaminated things like soiled clothing, bed linen, or used needles.
Doctors and other healthcare workers may be infected by Ebola disease through transmission or by coming in contact with infected bodily fluids. While it may be clear now that the Ebola virus is first transmitted from animals to humans and then from an infected human being to other humans. Some of the examples about how the Ebola virus gets transmitted to humans from an infected animal include the following. It can be transmitted through the blood of the infected animal like when someone butchers or eats such an infected animal.
Scientists who research upon and doctors who operate such infected animals may also contract the virus. Coming in contact with the feces or urine of infected animals can also cause transmission of the virus.
It should be made clear here that until a person develops the symptoms of Ebola infection, he or she does not become contagious and can not cause Ebola disease in others. Family members who take care of sick relatives infected with Ebola virus may catch the disease.
People who touch the infected dead body, such as during preparation for last rites, may also get the virus.
Doctors and healthcare professionals who do not use protective surgical masks and gloves etc. Reusing of needles and syringes that are used for an infected patient transmits the virus to another person. Symptoms alone cannot be used to diagnose Ebola virus disease as these may resemble the symptoms of other diseases such as cholera or malaria. There may be some other tests too that a doctor may deem fit to diagnose whether a person suffers from Ebola infection.
Till now, no antiviral medicine or drug has been proved to be effective against Ebola virus infection. In some advanced countries like USA, an experimental serum that destroys infected cells are also given to the patients.

According to the World Health Organization’s reports, as many as 80% of the people infected with Ebola virus die. The only way to survive from Ebola disease is to seek prompt medical care as soon as one comes in contact of the virus or at least when symptoms are seen. If you travel to a place where it is known to have Ebola virus disease such as in African countries. At present, there is no medicine or vaccine for Ebola virus disease though many researches are on to develop vaccines as well as medicines for Ebola virus disease.
If you are a caregiver for an infected person, avoid contact with patient’s body fluids and tissues which includes blood, semen, vaginal secretions and saliva. Health care worker should wear protective clothing like gloves, masks, gowns and eye shields. Here are some facts regarding Ebola virus and the disease caused by it to satisfy the curiosity of those who have it. The first human Ebola outbreaks were witnessed in 1976, one in northern Zaire (now Democratic Republic of the Congo) and the other, in southern Sudan (now South Sudan). Humans can get Ebola disease only when they come in contact with body fluids of an infected person or contaminated things of infected persons.
Human Ebola outbreaks have been confirmed in these countries- Democratic Republic of the Congo (DRC), Gabon, South Sudan, Ivory Coast, Uganda, Republic of the Congo (ROC), Guinea and Liberia. Ebola outbreaks leading to more than 100 deaths or special cases have been reported in the years 1976, 1989, 1990, 1995, 2000-01, 2001-02, Dec 2002- April 2003, 2007, Nov 2008, and the recent 2014. Ebola virus multiplies at a very fast rate until it reaches to a stage where about 100 million viral particles can be found in just a drop of blood. Proteins situated on the outer surface of the Ebola virus destroys the immune system of the infected person. Due to the absence of any effective treatment and a vaccine, raising awareness about the risk factors related to Ebola virus disease and the preventive measures are the only way to reduce human Ebola infections and deaths. It is characterized by recurring symptoms of reversible airflow obstruction and bronchospasm. But avoiding the allegens that cause asthma is the best way to avoid asthma attack or reduce the severity of asthma. Its classification depends upon the frequency of symptoms, forced expiratory volume(FEV), and peak expiratory flow rate. Caffeine is a brochodilator that may interfere with results of this test if taken before performing this procedure.
If there are some structural changes in air-way or alveoli or any other part of lungs it can be noticed by digital chest x-ray.
Low oxygenated air and high air pollution due to traffic pollution has been associated with both asthma development and increased asthma severity.
If any person having asthma problem in his family history then there will be 25-50% risk of development of asthma. Research has shown that diets low in antioxidants such as vitamin C and vitamin A, selenium, and omega-3 or high in sodium andomega-6 polyunsaturates are associated with an increased risk of asthma.Vitamin D has multiple role in body including its role in immunity.
It has been observed that there is some association between respiratory syncytial virus infection in infancy and the development of asthma, but specific pathogenesis is not clearly understood as this infection is very common in children.
This constriction of air-way leads to narrowing of airway passage and causes spasticity of bronchial smooth muscles and reduces its stretchability.
This inflammatory response is further aggravated by involvement of immune system including T lymphocytes, macrophages, and neutrophils. Methylxanthine’s main function regarding bronchodilation is to increase the concentration of cyclic AMP. Stimulation of these receptors via beta-2 agonists causes relaxation of bronchial smooth muscles. It can also be used in patients who have high grade of severity or sudden attach of asthma with prolong history of such problem. They are short acting and have rapid action while long acting have prolong action but slow onset. The most common causative agents of asthma include allergens,tobacco and other air pollutants.
Diet has also little effect in the management of asthma eating fresh vegetables ,consuming fresh juices and avoiding from eating too much junk food is a key of good health. Arslan MalikTags Asthma Asthma Care Cancer Care Health Care Devices Lung Disease Lungs Lungs CancerAbout Dr.
With doctor in pharmacy, he has worked closely with various health organizations, multinational pharmaceuticals and community health programs. Ebola virus has already gripped West African nations and till now, Ebola outbreak has recorded a fatality rate of about 80% which is quite a high number. Ebola can be defined as a group of viruses causing hemorrhagic fever as it leads to bleeding inside as well as outside infected body. It is actually transmitted from animals to humans and then it spreads from person to person by direct contact with the bodily fluids of such an infected person or animal. However, if you want to know how this transmission actually takes place, here are the facts about transmission of Ebola virus from animals and from humans. If a person is diagnosed with Ebola, he is immediately isolated from the public so that the disease can be prevented from spreading. Patients who need treatment are given supportive care and medicines for relief from symptoms. Generally, the aim of Ebola treatment is to treat the symptoms and to prevent secondary infections as well as complications such as pneumonia and liver failure.
However, the high rate of death is generally because of a drop in their blood pressure and failure of organs rather than from blood loss. Don’t buy them or eat them including nonhuman primates that are sold in local markets. Let the specially organized and trained teams to handle burials and other procedures regarding death rituals. Laboratory experiments suggest that even a single virus may be enough to lead to a fatal infection.
However, researchers believe that fruit bats are the most likely natural hosts for Ebola virus. The experimental drug Zmapp shows promising results but it is still in evaluation stage where its safety and efficacy has to be evaluated.

In a response to the virus, the molecules released by the immune cells are used by the virus to devastate the vascular system and activate blood clot formation.
Common manifestation of asthma are wheezing, coughing, chest tightness, and shortness of breath. The data further shows that most asthma related deaths occur in low and lower-middle income countries. Sometimes asthma is classified as atopic (extrinsic) asthma as or non-atopic (intrinsic) asthma. In 1873 a paper was published in modern medicine to explain the patho-physiology of the disease concluded that asthma can be cured by rubbing the chest with chloroform liniment. In 1950s Oral corticosteroids began to use for this condition while selective short acting beta agonist was brought into use in the 1960s. If the force respiratory volume measured by this method improves more than 12% following administration of a bronchodilator such as salbutamol, this is supportive of the diagnosis. Now, it is observed that increase in asthma rate is due to change in epigenetics factors and a changing living environment. Inhalation of toxic pollutants like volatile organic compounds for example hydrocarbons, chloroflouro carbons, lead and formaldehyde exposure have strong associations with development of environmental asthma.
It has been shown that about 25 genes are associated with asthma in some populations, including GSTM1, IL10, CTLA-4, SPINK5, LTC4S, IL4R and ADAM33. More recently, atypical bacteria such as Mycoplasma and Chlamydophila, have been implicated in the mechanism of severe asthma.
For example toluene di-isocyanate and trimellitic anhydride may cause atopic or extrinsic asthma. There may also be involvement of other components of the immune system including: cytokines, chemokines, histamine, and leukotrienes among others.
Long term asthma treatment and management requires regular doses of these leukotriene inhibitors because they inhibit the release of leukotrienes. Now a day number of corticosteroids are used in longterm management of asthma for example fluticasone,beclomethasone and budesonide. These drugs have multiple effects like relaxation of bronchial smooth muscles,increase in CAMP level and stimulation of beta-2 receptors present on bronchial smooth muscles.
Cigarette smoking and passive smoke may reduce the effectiveness of medications such as corticosteroids. Beside his professional practice, he has an avid interest in writing and teaching Physiology and Medicines. Keeping in view the ever shrinking globe, Ebola virus can shock anybody in any country with its presence. To be precise, Ebola virus causes an infectious and fatal disease which shows itself as fever and severe internal bleeding. This virus lives in animal hosts and has been found in African monkeys, chimps and other nonhuman primates. According to scientists, there are five different types of the virus that can infect humans.
Severely ill patients are given intensive supportive care along with intravenous fluids or oral rehydration with solutions containing electrolytes. If the travel to such place can’t be avoided, find out about the current epidemic outbreaks. Atopic means asthma due to some allergens that may cause type 1 hypersensitivity reactions like pollens. Toxic polymers like phthalates and PVC(poly vinyl chloride) are associated with development of asthma in children. Many of these genes are related to the immune system or modulating inflammation.This observation suggest that there is complex interaction between these genes and environmental factors that aggravate inflammation and production of inflammatory triggers such as leukotrienes,platelet aggregation factors, neutrophils and macrophages that will lead to inflammatory response.
Individuals may also be exposed to allergens in the workplace such as small animal allergens in laboratory workers and fungal amylase in wheat flour in bakers.
He covers variety of topics from Nutrition and Natural Care to Diseases, Treatments, Drug Interactions, Preventive Care and Clinical Research. The only key to save oneself and dear ones from Ebola virus infection is creating awareness and taking steps to prevent it. Incubation period is the time between the exposure to the virus to the time when a person feels and sees the symptoms. World Health Organization (WHO) says that Ebola disease can be caused by close contact with the blood, secretions, organs or other bodily fluids of infected animals. When soap and water are not available, use alcohol-based hand rubs that contain at least 60% alcohol. Obesity is also an independent risk factor for asthma, particularly in women,but the mechanisms are thus far unknown. Regular exercise and healthy activities are very beneficial life style modifications to cope with asthma. Here is all about Ebola virus- what are the causes of Ebola infection, its symptoms, diagnosis, treatment and prevention- the facts about Ebola virus to help you keep distance from this very dangerous infection. Having quite a long incubation period (8 to 21 days), Ebola viral infection can gradually lead to organ failure and, in many cases, death.
Once Ebola virus contracts a human being, it can then spread from one person to another and so on, primarily through contact with body fluids or contaminated needles. Even after this incubation period, the patient can only see the early symptoms like fever, headache, body pains and aches, weakness etc. Over time, the symptoms of Ebola worsens and may include vomiting, diarrhea, rashes, stomach pain, bleeding etc. If someone is diagnosed with Ebola, supportive care and treatment for complications are given by the doctors.
Here is the list of early symptoms as well as severe symptoms that show off after some time.

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