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20.04.2014, admin
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It's hard to decide which is the crazier part of birth control pills' journey from experimental contraception to a federally approved drug. Development on the birth control pill began in 1950, when Planned Parenthood founder Margaret Sanger approached a scientist named Gregory Pincus to begin work on a reliable, easy-to-use contraceptive.
In the middle of the 20th century, it was still illegal to distribute contraceptives in some states.
When the Food and Drug Administration approves a drug these days, it has usually been tested on thousands of patients during three specific testing phases that can take more than a decade to complete. Testing in the state hospital did not turn out to be especially helpful for reasons that, in hindsight, were completely predictable. John Rock is a pivotal character in Eig's book and in the development of the birth control pill. If you signed up using a 3rd party account like Facebook or Twitter, please login with it instead. In order to provide our users with a better overall experience, we ask for more information from Facebook when using it to login so that we can learn more about our audience and provide you with the best possible experience.
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Was it when they were tested on non-consenting, male patients at mental hospitals — or when some women were given the pill as a treatment for infertility? Pincus was working at an independent lab in Massachusetts, the Worcester Foundation for Experimental Biology. The pill ultimately became an integral and important resource for millions of women, allowing them to take control of their fertility, their families, and their lives. I recently spoke with its author, Jonathan Eig, about the surprising and unsettling history behind oral contraceptives. This presented a challenge for researchers who were developing them: it was illegal to distribute their product to the women they would need for trials. Working in Puerto Rico was easier because the territory did not bar the distribution of birth control. Eig interviewed Enoch Calloway, who worked at Massachusetts' Worcester State Hospital when Pincus tested the pill there. He was an obstetrician and gynecologist based in Marlborough, Massachusetts, who recruited the first women for Pincus' birth control trials. We do not store specific user data and the sharing of it is not required to login with Facebook.
But the path to building this-now ubiquitous drug was paved with questionable ethics and dodgy research methods that would never pass muster today.
Even back then, Pincus and his team of researchers knew the FDA would find this tiny cohort suspect.
The creators of birth control are responsible for developing a revolutionary contraceptive — but they misled their test subjects, many of whom were not equipped to give consent, along the way.
The researchers' solution ultimately boiled down to manipulating women, recruiting college students and threatening them with bad grades if they didn't participate in trials.
He saw the challenges his patients faced with unplanned pregnancies, and he was able to reconcile his faith and his personal beliefs.


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A recent study published in the American Association for Cancer Research journal Cancer Research suggests that women who take birth control pills containing high doses of estrogen, ethynodiol diacetate, and norethindrone significantly increase their risk of developing breast cancer."Our results suggest that use of contemporary oral contraceptives [birth control pills] in the past year is associated with an increased breast cancer risk relative to never or former oral contraceptive use, and that this risk may vary by oral contraceptive formulation," Dr. Beaber, a staff scientist in the Public Health Sciences Division of Fred Hutchinson Cancer Research Center in Seattle, said in a statement.Beaber and her colleagues recruited 1,102 women diagnosed with breast cancer and 21,952 healthy women from the Group Health Cooperative in the Seattle-Puget Sound area.
Electronic pharmacy records were also used to gather information on different oral contraceptives, including the name of each drug, dosage, and duration. Oral contraceptives containing low-dose estrogen had no effect on a woman’s risk of developing breast cancer.
In addition, prior studies suggest that the increased risk associated with recent oral contraceptive use declines after stopping oral contraceptives."According to the American Cancer Society, around 232,670 new breast cancer diagnoses are expected for 2014 in the United States.
Although a string of recent studies have tied oral contraceptives to an increased risk of developing breast cancer, a woman’s risk seems to dissipate 10 years after stopping her birth control regimen. Recent Oral Contraceptive Use by Formulation and Breast Cancer Risk among Women 20 to 49 Years of Age. Cancer Research.




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