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The optimal aminoglycoside and its dosage for the treatment of severe Enterococcus faecalis infection.
08 March 2012The optimal aminoglycoside and its dosage for the treatment of severe Enterococcus faecalis infection. Aminoglycosides are recommended for the treatment of Enterococcus faecalis infections, especially in severe and bacteremic infection.
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Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer.
Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heart. The in vivo efficacy was assessed according to the bacterial count in vegetations, in comparison with a control group. Of the four aminoglycosides tested, only gentamicin and netilmicin showed significant antibacterial efficacy after 3 days of treatment.

Among the tested aminoglycosides, gentamicin showed the best efficacy, with the best results after 24 h of treatment for the highest dosage.

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