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I have been emphasizing the virtues of magnesium threonate lately to medical professionals. Learning is the process by which the brain is able to store new information by forming new connections between neurons in what are called networks.
Synapse formation is dependant upon a variety of factors that have been well studied including insulin, ghrelin, various trophic hormones, and, as we have now learned, the ion magnesium, which enhances the activity of more than 300 enzymes.
It has now been discovered that magnesium is a critical player in the activation of nerve channels that are involved in synaptic plasticity. As it turns out, one form of magnesium, magnesium threonate, has the unique ability to permeate the brain and enhance the receptors that are involved in this process.
As reported in the journal Neuron researchers demonstrated actual enhancement in the learning abilities, working memory, as well as short as well as long-term memory and even quality of sleep, in laboratory animals, who were given magnesium magnesium threonate. One of the most aggressively studied forms of magnesium threonate is a patented product called Magteina, developed by researchers at MIT including a Nobel Prize winner. This entry was posted in eating, mind & brain and tagged brain, brain health, david perlmutter, david perlmutter md, dr.
Magnesium taurate is a wonderful supplement that can do great things for your brain and heart.
If I had to pick out one brain supplement as my absolute favorite, my answer might come as a bit of a surprise: magnesium taurate. 3) Other enzymes magnesium activates serve your body by improving the effectiveness of the energy glucose gives us. Magnesium taurate offers us all the positives of other forms of magnesium, but it doesn’t affect the stomach in the way those other forms can. However, even if you are fortunate enough to suffer from none of the above, you should still consider taking this supplement. I believe magnesium taurate to be the best supplement I have ever tried (and I’ve tried plenty). Whether it is the latest research on how to reduce heart disease, slow the aging process, or prevent brain aging, Life Extension® reports it first. November is National Alzheimer’s Awareness Month and the serious issues of cognitive health will be in the spotlight in the coming weeks. The solution is still unclear, however the good news is that the human brain has a greater degree of plasticity than scientists previously believed, and new studies, specifically those made in nutritional research, show that magnesium deficiency in adults may play a more important role in CI, and more seriously, Alzheimer’s Disease (AD), than previously thought.
Furthermore, he states, “There is no question that cognitive impairment is a major fear and health issue for the nation. According to the Centers for Disease Control and Prevention, estimates show that approximately 20% of people ages 55 and older will experience some form of cognitive impairment. Cilantro imports banned following discovery of human feces in fields linked to outbreaks of cyclosporiasis in U.S. New study finds NSAIDs increase risk of stroke, heart attack and death in postmenopausal women by up to 10 percent. You must have JavaScript enabled in your browser to utilize the functionality of this website.
Cognition refers to our capacity to acquire and retrieve information, execute decisions, navigate our surroundings, solve problems and effectively communicate.


In the process of acquiring and storing information, new synapses materialize while others recede.
An essential cofactor with extensive involvement in homeostatic and adaptive neuronal processes, magnesium is an indispensable participant in synaptic plasticity and density. A research team at the Massachusetts Institute of Technology (MIT), including a Nobel Prize laureate, has identified a form of magnesium that crosses the blood-brain barrier. McKee JA, Brewer RP, Macy GE, Phillips-Bute B, Campbell KA, Borel CO, Reynolds JD, Warner DS.
Slutsky I, Abumaria N, Wu LJ, Huang C, Li B, Govindarajan A, Zhao MG, Zhuo M, Tonegawa S, Liu G. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. I think it would be good to actually review some of the information about an exciting new area of chemistry related to neuronal function and brain function in general.
That means that magnesium is critical for the physiological events that are fundamental to the processes of learning and memory. Their research has demonstrated actual restoration of function in aging neurons in laboratory animals.
David Perlmutter is recognized internationally as a leader in the field of nutritional influences in neurological disorders. These are primarily not used for the brain but for cleansing the body of toxins, and also for digestion. Magnesium therefore helps the body use that energy more efficiently – which indirectly improves the amount of energy which can be used by the brain.
To make it better still, the two chemicals work together synergistically – in other words, in concert the effects of both are stronger.
Magnesium taurate will help your brain function better, it will help your heart (including reducing the likelihood of arrhythmias), and it will promote a feeling of goodwill, calmness and focus.
The medical community agrees that cognitive impairment (CI), ranging from mild to severe, is almost epidemic in the U.S. Guosong Liu, one of the world’s leading cognitive health researchers, suggest that elevation of brain magnesium through dietary intake of magnesium threonate exerts substantial positive effects on brain synapes in a mouse model of AD, actually restoring aging brains to their youthful conditions.
Liu said, “The body of our peer-reviewed and published work underscores that magnesium threonate can help maintain healthy brain activity.
People are living longer and they want to take steps to maintain the quality of their physical and mental health. Peter Osborne, a Board Certified doctor of clinical nutrition, said, “Healthy cognitive function begins with a solid nutritional foundation. Meet the Tiny Part of Your Brain That Imagines How Bad Things Could Be'Catastrophizing' is described by pscyhologists as cognitive distortion. In the clinical setting, these faculties are collectively expressed by two familiar terms—learning and memory. Known as synaptic plasticity, this dynamic remodeling constitutes the cellular basis of learning. Magnesium is so important to brain function that the body maintains higher concentrations in the cerebrospinal fluid than in the bloodstream.


Magnesium-l-threonate (Magtein™), effectively enriches brain magnesium when taken orally. This facet of cognition enables us to locate our car keys, remember where our car is parked, where we live and how to navigate to a destination.
Evaluation of magnesium concentration in the cerebrospinal fluid following administration of different magnesium compounds. Magnesium-l-threonate offered statistically significant support for memory and cognitive function in both young and old animals.
Analysis of the brain bioavailability of peripherally administered magnesium sulfate: A study in humans with acute brain injury undergoing prolonged induced hypermagnesemia. Food for thought: the role of dietary flavonoids in enhancing human memory, learning and neuro-cognitive performance. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. This process depends on the actual formation of these connections, as well as the number of connections that are available.
He serves as medical director of the Perlmutter Health Center in Florida and is an adjunct instructor at the Institute for Functional Medicine.
This is largely down to changes in farming practices, which mean magnesium is lacking in the soil, and therefore lacking in the food that comes from the soil. Among the many benefits of taurine are the heightened control of neurotransmitters in the brain – which can prevent the death of brain cells (and consequently the onset of brain dysfunction and even brain damage). The study is the first to show a mechanism for reversing cognitive decline in advanced stage AD mice, and is also the first to show an effective long-term treatment in AD mice.* More exciting, though, are the implications of this study for the potential for treating AD in humans.
There is no doubt that magnesium threonate has dramatic effects in preventing synapse loss and reversing memory decline in mice with Alzheimer’s disease. Cognitive impairment can affect a person’s memory, language, perception, ability to plan and carry out tasks, and judgment. Memory is orchestrated by both synaptic plasticity and adaptive concentration of synaptic structures, known as synaptic density. Upon comparison with magnesium chloride, citrate and gluconate, only Magtein™ produced significant increases in the cerebrospinal magnesium concentrations of rats (Figure 1). Perlmutter is the author of the #1 New York Times Bestselling book Grain Brain and the author of Power Up Your Brain: The Neuroscience of Enlightenment and The Better Brain Book . A recently concluded double blind, placebo-controlled human study, the ‘gold standard’ of science, demonstrates that dietary supplementation of Magtein, patented magnesium threonate, can significantly enhance human cognitive functions and decrease symptoms of cognitive impairments.” The study is expected to be published in a leading peer-reviewed journal in 2014. We know 50 million Americans are magnesium deficit because people do not eat enough foods that contain magnesium. Two factors — longer life spans and aging baby boomers — will combine to double the population of American’s aged 65 years or older during the next 25 year to about 72 million.



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