Martin and his team at the University of Toronto conducted studies on mice and identified a gut bacteria that fuels cancer growth by converting carbs into cancer-spurring metabolites. This is because nearly all the healthy cells in our body have the metabolic flexibility to use fat, glucose and ketones to survive, but cancer cells lack this metabolic flexibility and require large amounts of glucose and cannot survive on ketones. While this idea may sound new to us lay people, scientists have been aware of this for the past 80 years. The “Warburg effect” can be exploited by the ketogenic diet, but so far this approach has not been used to fight cancer. In addition to fueling weight loss, the low-carb, high-fat ketogenic diet has been shown to combat a variety of different diseases, including epilepsy, diabetes, Alzheimer's, and heart disease. Seyfried joins a growing number of scientists who say the LCHF ketogenic diet is a promising alternative to the current standard of care. The results indicated that six of the 10 patients responded well to the ketogenic diet, meaning their cancers stabilized or showed partial remission.
Cannes Film Festival fashion: Amal Clooney, Blake Lively, Victoria BeckhamThe 69th Cannes Film Festival opened on Wednesday, May 11 with Woody Allen's new film. Ways to earn extra money: The side hustleRemember when a full-time job used to mean working 40 hours a week or more and bringing home a decent paycheck that would last, at least until the next pay check? The studies consistently show that when people cut carbs and eat more protein and fat, they end up eating much fewer calories. In fact… when researchers are comparing low-carb and low-fat diets in studies, they need to actively restrict calories in the low-fat groups to make the results comparable (2).
One of the reasons for this is that low-carb diets tend to get rid of excess water from the body.
In studies comparing low-carb and low-fat diets, the low-carbers sometimes lose 2-3 times as much weight, without being hungry (5, 6). Low-carb diets appear to be particularly effective for up to 6 months, but after that the weight starts creeping back up because people give up on the diet and start eating the same old stuff (7). Visceral fat is fat that tends to lodge around the organs. Having a lot of fat in that area can drive inflammation, insulin resistance and is believed to be a leading driver of the metabolic dysfunction that is so common in Western countries today (8). When people cut carbs, they tend to have a very dramatic reduction in blood triglycerides (14, 15). Compare this to low-fat diets, which can cause triglycerides to go up in many cases (16, 17). Whereas LDL carries cholesterol from the liver and to the rest of the body, HDL carries cholesterol away from the body and to the liver, where it can be reused or excreted.
For people who are healthy, the quick insulin response tends to minimize the blood sugar “spike” in order to prevent it from harming us. However… many, many people have major problems with this system. This can lead to a disease called type 2 diabetes, when the body fails to secrete enough insulin to lower the blood sugar after meals. If you are currently on blood sugar lowering medication, then talk to your doctor before making changes to your carbohydrate intake, because your dosage may need to be adjusted in order to prevent hypoglycemia.
Unfortunately, the government and major health organization still recommend a low-fat diet for this purpose, which is pretty much useless because it does nothing to address the underlying metabolic problem.
This is the mechanism behind the ketogenic diet, which has been used for decades to treat epilepsy in children who don’t respond to drug treatment (44). In many cases, this diet can cure children of epilepsy. In a press release July 18, UT researchers said their studies indicate a low-carb diet can stem cancer growth by up to 75 percent. Following a low-carb diet dramatically reduced the spread of cancer, said Martin, who published his findings in the medical journal Cell. Seyfried, widely considered the godfather of the nutritional treatment of cancer, joins a growing number of researchers who say the ketogenic diet can treat most forms of cancer.
So by limiting carbohydrates (as the keto diet does) we can reduce glucose and insulin, and thus restrict the primary fuel for cancer cell growth.
This phenomenon was first observed in the 1920s by German physiologist Otto Warburg, who won a Nobel Prize in 1931 for discovering that cancer cells have defective mitochondria and thrive on sugar. One is Joe Mancaruso, a 56-year-old Texas man, who told me he has been battling terminal lung cancer without chemotherapy using the ketogenic diet. Seyfried said the time has come for the medical community to publicly acknowledge the viability of the ketogenic diet as an inexpensive, non-toxic way to treat cancer.
Low-Carb Diets Lead to More Weight Loss Cutting carbs is one of the simplest and most effective ways to lose weight. Studies show that people on low-carb diets lose more weight, faster, than people on low-fat diets… even when the low-fat dieters are actively restricting calories.
Because they lower insulin levels, the kidneys start shedding excess sodium, leading to rapid weight loss in the first week or two (3, 4).
The only way to succeed in the long-term is to stick to it. However, some people may be able to add in healthy carbs after they have reached their goal weight. The higher it is, the greater your risk of heart disease is (26, 27, 28). By lowering triglycerides and raising HDL levels, low-carb diets lead to a major improvement in this ratio.
They have what is called insulin resistance, which means that the cells don’t “see” the insulin and therefore it is harder for the body to bring the blood sugar into the cells (29). This disease is very common today, afflicting about 300 million people worldwide (30). There is actually a very simple solution to this problem… by cutting carbohydrates, you remove the need for all of that insulin. Low-Carb Diets Are The Most Effective Treatment Known Against Metabolic Syndrome Metabolic syndrome is a medical condition that is highly associated with the risk of diabetes and heart disease. People who have mostly small particles have a high risk of heart disease, while people who have mostly large particles have a low risk (40, 41, 42). It turns out that low-carb diets actually turn the LDL particles from small to large, while reducing the number of LDL particles floating around in the bloodstream (43). Low-Carb Diets Are Therapeutic For Several Brain Disorders It is often claimed that glucose is necessary for the brain… and it’s true. Some part of the brain can only burn glucose. In one study, over half of children on a ketogenic diet had a greater than 50% reduction in seizures. Seyfried's decades of research indicates cancer is a metabolic disease that can best be treated with the low-carb, high-fat ketogenic diet. Today, there are about a dozen studies that are investigating the use of the ketogenic diet to manage all kinds of cancer. Dominic D'Agostino of the University of South Florida agrees cancer is a metabolic disease that can be managed with the ketogenic diet. The patients all had advanced cancers and agreed to follow a ketogenic diet (which for limited daily carb intake to less than 50 grams) for 28 days. Adrienne Scheck of the Barrow Brain Tumor Research Center also said the ketogenic diet can be an effective tool to manage deadly brain cancer. That’s why the liver produces glucose out of protein if we don’t eat any carbs. But a large part of the brain can also burn ketones, which are formed during starvation or when carbohydrate intake is very low.
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