Post-traumatic stress disorder occurs after a person is exposed to a traumatic event, though not everyone that experiences or witnesses such an event is affected by the condition. Researchers from the University of California in Los Angeles (UCLA) have identified two gene variants that could influence the risk of post-traumatic stress disorder (PTSD).
According to the National Institute of Mental Health (NIMH), 6.8% of the adult population of the US experience PTSD at some point in their lifetime. Symptoms can vary in intensity over time and can be triggered by reminders of the traumatic event that caused the disorder to occur in the first place.
Previous research in 2012 involving these samples led to the discovery that survivors carrying two gene variants associated withdepression were more likely to have PTSD than those that did not carry the variants. For the study, published in the Journal of Affective Disorders, the team assessed the roles of two genes in the DNA samples, taken from 200 individuals.
Anyone can be exposed to a traumatic event and be affected by PTSD, regardless of age and gender.
Recently, Medical News Today reported on a study finding that women experiencing large numbers of PTSD symptoms could have almost two times the risk of developing type 2 diabetes compared with women who have not been exposed to trauma.
New genetic research may now explain why some people develop the condition while others do not. This discovery could lead to improvements in the diagnosis and treatment of PTSD in the future. Goenjian traveled to Armenia in 1988 after a 6.8 magnitude earthquake hit the country, destroying many cities and killing more than 25,000 Armenians. The genes were COMT, an enzyme that degrades the mood regulator dopamine, and TPH-2, a controller of the production of serotonin. Goenjian says the team hopes that the study’s findings will lead to molecular methods for screening people at risk for PTSD and identify new forms of drug therapy to prevent and treat the disorder.
During this time, many families agreed to have blood samples sent to UCLA so that the team could analyze their DNA for information pertaining to psychiatric vulnerability. He recommends that research into this area continues in a bid to uncover more of the genes involved.
Genes and inherited traits may play a role determining an individual’s risk of developing PTSD. Researchers from the University of California in Los Angeles (UCLA) have identified two gene variants that could influence the risk of post-traumatic stress disorder (PTSD). This site complies with the HONcode standard for trustworthy health information: verify here.
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