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Obesity-related conditions include heart disease, stroke, type 2 diabetes and certain types of cancer, some of the leading causes of preventable death.
Approximately 17% (or 12.7 million) of children and adolescents aged 2 - 19 years had obesity. Using the intestinal hormone GLP-1 in obesity treatment prevents the loss of bone mass otherwise frequently associated with major weight loss. The study looked at 37 women who achieved a large weight loss of 12 kg by eating a low-calorie diet.
The importance of intestinal hormones on bone formation and breakdown has long been a focus area. A Pragmatist's Guide for LivingIt's easy to make a financial decision based on what you need right now, but making an informed choice will benefit you in the long run.
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This is the finding of a new study from the University of Copenhagen, Hvidovre and Glostrup Hospital. New research shows that treating obesity with the GLP-1 hormone helps prevent loss of bone mass in addition to having a number of positive effects on the formation of new bone and on blood sugar levels. Liraglutide has just been approved for obesity treatment because of its appetite-inhibiting effects, but its effect on the bones of overweight patients who are not suffering from type 2 diabetes has so far been unknown,” says physician and PhD student Eva Winning Jepsen from the Department of Biomedical Sciences and the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.
The women were divided into two groups: one which was given the GLP-1 analogue liraglutide, and a control group. If they try to lose weight and thus lose even more bone mass, they are at an even higher risk. This study now opens up for exploiting the beneficial effect of intestinal hormones on the bones. It appears that treatment with liraglutide makes it possible to lose weight and maintain the beneficial effect on the bones, while at the same time reducing the risk of cardiovascular disease and type 2 diabetes. With only 45 calories and 1 PointsPlus ® per serving, it is the best peanut butter replacement. You can make noodles out of virtually any veggies - zucchini, summer squash, and carrots are my favorite.
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Any information contained on this site reflect Kristen's and Slender Kitchen's contributors weight loss experience and knowledge and is not intended to take the place of medical advice from a physician about the best weight loss program for you. According to the researchers behind the study, the results may have a significant bearing on future obesity treatment. Over a one-year period, the women were given frequent dietary advice to help them maintain their weight loss; and if they gained weight, they could replace up to two meals with a low-calorie powder.
The study shows that overweight women can now lose weight with liraglutide without increasing the risk of losing bone mass. This may have a significant bearing on our future approach to obesity treatment,” says Signe Soerensen Torekov. It works great as a powder in smoothies and recipes, or mixed with water for sandwiches, dips, and snacks. The texture isn't for everything but I use them all the time in salads, stir-frys, and soups. At the same time, they also achieve a number of other positive effects on their sugar metabolism which are not achieved through a diet-induced weight loss alone,” says Associate Professor Signe Soerensen Torekov - who is heading the study - from the Department of Biomedical Sciences and the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.
The women in the control group had maintained their weight by replacing one meal a day with a low-calorie diet. The study showed that the liraglutide group had not lost any bone mass and had increased blood levels of bone formation markers as opposed to the control group which had lost bone mass.
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